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Anti-Plaque Efficacy of Herbal and 0.2% Chlorhexidine Gluconate Mouthwash: A Comparative Study.

Prasad KA, John S, Deepika V, Dwijendra KS, Reddy BR, Chincholi S - J Int Oral Health (2015)

Bottom Line: There was no significant difference in the gingival index (GI) and plaque index (PI) scores of the pre-rinsing scores of three groups and mean age of subjects in the three age groups, suggesting selected population for the three groups was homogenous.The difference of post rinsing PI and GI scores between Group A and Group B were statistically non-significant, which means anti-gingivitis and plaque inhibiting properties are similar for both.Within the limitations of this study chlorhexidine gluconate and herbal mouthwash (Hiora) showed similar anti plaque activity with latter showing no side effects.

View Article: PubMed Central - PubMed

Affiliation: Professor, Department of Periodontics, MNR Dental College and Hospital, Sangareddy, Telangana, India.

ABSTRACT

Background: Mouthwashes are an adjunct to, not a substitute for, regular brushing and flossing. Chlorohexidine is cationic bis-biguanide broad spectrum antiseptic with both anti-plaque and antibacterial properties. It has side-effects like brownish discoloration of teeth and dorsum of the tongue, taste perturbation, oral mucosal ulceration, etc. To compare the antiplaque efficacy of herbal and chlorohexidine gluconate mouthwash.

Materials and methods: A double-blinded parallel, randomized controlled clinical trial was conducted in the Department of Periodontics, MNR Dental College. Totally 100 preclinical dental students were randomized into three groups (0.2% chlorohexidine, Saline and herbal mouthwash). All the groups were made to refrain from their regular mechanical oral hygiene measures and were asked to rinse with given respective mouthwashes for 4 days. The gingival and plaque scores are evaluated on 1(st) day, and 5(th) day, and differences were compared statistically.

Results: There was no significant difference in the gingival index (GI) and plaque index (PI) scores of the pre-rinsing scores of three groups and mean age of subjects in the three age groups, suggesting selected population for the three groups was homogenous. Mean GI and PI scores at the post rinsing stage were least for the Group A, followed by B and C. The difference of post rinsing PI and GI scores between Group A and Group B were statistically non-significant, which means anti-gingivitis and plaque inhibiting properties are similar for both.

Conclusion: Within the limitations of this study chlorhexidine gluconate and herbal mouthwash (Hiora) showed similar anti plaque activity with latter showing no side effects.

No MeSH data available.


Related in: MedlinePlus

Means of all the three groups. (1) Pre gingival index, (2) Post gingival index, (3) Pre plaque index, (4) Post plaque index.
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Figure 4: Means of all the three groups. (1) Pre gingival index, (2) Post gingival index, (3) Pre plaque index, (4) Post plaque index.

Mentions: Tables 2 and 3 show, significant difference between CHXG versus Saline and Hiora versus Saline post rinse after 5th day in index and highly significant difference (P <0.001) was seen in PI in post rinse group after 5th day i.e., CHXG versus Saline and Hiora versus Saline signifies that CHXG and Hiora are effective in removal of plaque than the control. The intra group comparison shows the scores were significantly lower for the three groups at the baseline when compared with the post rinse scores. The results of this study signifies a greater increase in scores of both plaque and gingival indices and the intra group comparison shows there was a significant difference between the two groups and CHXG showed more significant decrease in plaque and gingival scores when compared with the other two. The baseline scores were lower for the GI and PI scores when compared with follow-up or post in all the groups (Graph 1).


Anti-Plaque Efficacy of Herbal and 0.2% Chlorhexidine Gluconate Mouthwash: A Comparative Study.

Prasad KA, John S, Deepika V, Dwijendra KS, Reddy BR, Chincholi S - J Int Oral Health (2015)

Means of all the three groups. (1) Pre gingival index, (2) Post gingival index, (3) Pre plaque index, (4) Post plaque index.
© Copyright Policy - open-access
Related In: Results  -  Collection

License
Show All Figures
getmorefigures.php?uid=PMC4588801&req=5

Figure 4: Means of all the three groups. (1) Pre gingival index, (2) Post gingival index, (3) Pre plaque index, (4) Post plaque index.
Mentions: Tables 2 and 3 show, significant difference between CHXG versus Saline and Hiora versus Saline post rinse after 5th day in index and highly significant difference (P <0.001) was seen in PI in post rinse group after 5th day i.e., CHXG versus Saline and Hiora versus Saline signifies that CHXG and Hiora are effective in removal of plaque than the control. The intra group comparison shows the scores were significantly lower for the three groups at the baseline when compared with the post rinse scores. The results of this study signifies a greater increase in scores of both plaque and gingival indices and the intra group comparison shows there was a significant difference between the two groups and CHXG showed more significant decrease in plaque and gingival scores when compared with the other two. The baseline scores were lower for the GI and PI scores when compared with follow-up or post in all the groups (Graph 1).

Bottom Line: There was no significant difference in the gingival index (GI) and plaque index (PI) scores of the pre-rinsing scores of three groups and mean age of subjects in the three age groups, suggesting selected population for the three groups was homogenous.The difference of post rinsing PI and GI scores between Group A and Group B were statistically non-significant, which means anti-gingivitis and plaque inhibiting properties are similar for both.Within the limitations of this study chlorhexidine gluconate and herbal mouthwash (Hiora) showed similar anti plaque activity with latter showing no side effects.

View Article: PubMed Central - PubMed

Affiliation: Professor, Department of Periodontics, MNR Dental College and Hospital, Sangareddy, Telangana, India.

ABSTRACT

Background: Mouthwashes are an adjunct to, not a substitute for, regular brushing and flossing. Chlorohexidine is cationic bis-biguanide broad spectrum antiseptic with both anti-plaque and antibacterial properties. It has side-effects like brownish discoloration of teeth and dorsum of the tongue, taste perturbation, oral mucosal ulceration, etc. To compare the antiplaque efficacy of herbal and chlorohexidine gluconate mouthwash.

Materials and methods: A double-blinded parallel, randomized controlled clinical trial was conducted in the Department of Periodontics, MNR Dental College. Totally 100 preclinical dental students were randomized into three groups (0.2% chlorohexidine, Saline and herbal mouthwash). All the groups were made to refrain from their regular mechanical oral hygiene measures and were asked to rinse with given respective mouthwashes for 4 days. The gingival and plaque scores are evaluated on 1(st) day, and 5(th) day, and differences were compared statistically.

Results: There was no significant difference in the gingival index (GI) and plaque index (PI) scores of the pre-rinsing scores of three groups and mean age of subjects in the three age groups, suggesting selected population for the three groups was homogenous. Mean GI and PI scores at the post rinsing stage were least for the Group A, followed by B and C. The difference of post rinsing PI and GI scores between Group A and Group B were statistically non-significant, which means anti-gingivitis and plaque inhibiting properties are similar for both.

Conclusion: Within the limitations of this study chlorhexidine gluconate and herbal mouthwash (Hiora) showed similar anti plaque activity with latter showing no side effects.

No MeSH data available.


Related in: MedlinePlus