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Oral Health Related Quality of Life in Patients of Head and Neck Cancer Attending Cancer Hospital of Bhopal City, India.

Shavi GR, Thakur B, Bhambal A, Jain S, Singh V, Shukla A - J Int Oral Health (2015)

Bottom Line: Main factors affecting QoL were loss of weight, use of painkillers, sticky saliva, reduced mouth opening and problems in social eating.Significant association found between pain (P = 0.044), swallowing (P = 0.018), sense (P = 0.001), Social eating (P = 0.003), social contact (P = 0.008), reduced mouth opening (P = 0.008) with respect to type of treatment.We conclude that there was a significant reduction in the QoL in cancer patients resulting from myriad forms of cancers.

View Article: PubMed Central - PubMed

Affiliation: Professor & Head, Department of Public Health Dentistry, Rajasthan Dental College and Hospital, Jaipur, Rajasthan, India.

ABSTRACT

Background: To assess the oral health related quality of life (OHRQoL) of head and neck cancer patients and to find association between QoL, demographic and disease variables.

Methods: This cross-sectional study was conducted on 153 patients diagnosed and being treated for head and neck cancer in Jawaharlal Nehru Cancer Hospital, India. Data collected from the survey included demographic details and OHRQoL, which was measured by European Organization of Research for Treatment of Cancer QoL questionnaire head & neck-35. Cancer measurements (location of tumor, stages of cancer, treatment type) were collected from the patient's hospital records.

Results: The majority of the population 84 (54.9%) belonged to 41-60 years age group and most of them were male (78.4%). The most frequent site of the primary tumor was the oral cavity (71.3%) and the majority of patients had Stage II and III cancer. Main factors affecting QoL were loss of weight, use of painkillers, sticky saliva, reduced mouth opening and problems in social eating. Significant association found between pain (P = 0.044), swallowing (P = 0.018), sense (P = 0.001), Social eating (P = 0.003), social contact (P = 0.008), reduced mouth opening (P = 0.008) with respect to type of treatment.

Conclusions: We conclude that there was a significant reduction in the QoL in cancer patients resulting from myriad forms of cancers. An assessment of the QoL and symptoms can help the dentist to direct attention to most important symptoms and provide counseling for appropriate interventions towards improving QoL outcomes and the response to the treatment.

No MeSH data available.


Related in: MedlinePlus

Percentage distribution of domains and single itemsaccording to mean value.
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Figure 1: Percentage distribution of domains and single itemsaccording to mean value.

Mentions: The study population consisted of 153 patients diagnosed with HNC and receiving treatment. Patients’ characteristics for the whole study group are shown in Tables 1 and 2. Among the cancer patient’s males comprised the majority of the study population i.e., 120 (78.4%). 84 (54.9%) belonged to 41 and 60 years age group. Most of them were married (148, 96.7%), the majority of subjects belonged to upper lower class 55 (35.9%) (Table 1). 95 (62.1%) HNC patients had smokeless tobacco and majority of duration of tobacco chewing 69 (45.1%) were more than 15 years. For ease of analysis we divided site of cancer into four categories. Buccal mucosa, tongue, alveolus, maxilla, mandible, gingivo buccal sulcus and pyrifossa were clubbed into a single category i.e., oral cavity. The remaining three categories were oropharynx, hypopharynx and larynx respectively. majority of cancers originated in oral cavity i.e., 118 (77.12%). At the time of study 83 (54.2%) population presented with Stage II cancer and majority of the patients 88 (57.6%) were diagnosed within 6 months. The most administered form of treatment was radiation + surgery therapy 39 (25.5%) followed by radiation therapy 38 (24.8%). The QLQ-H&N35 specific questionnaire, Graph 1 shows the mean value of all the domains and single items. High mean score shows worst symptoms response. So, according to mean value the main factors affecting QoL were lost weight (79.08), taking painkiller (75.82), sticky saliva (72.75), reduced mouth opening (68.17) and difficulty in social eating (69.10). The scales and single items of QoL questionnaire were compared according to sites of tumor, stage of cancer, type of treatment method. Table 3 shows patients with small tumors (Stage I+II) scored better than those with large tumors (Stage III+IV). Patients with large tumor (Stage III+IV) had worst value for swallowing (P = 0.00), speech (P = 0.00), social eating (P = 0.00), social contact (P = 0.001), reduced mouth opening (P = 0.00), dry mouth (P = 0.001), cough problem (P = 0.00) feeling of being ill (P = 0.00) and use of feeding tube (P = 0.050).


Oral Health Related Quality of Life in Patients of Head and Neck Cancer Attending Cancer Hospital of Bhopal City, India.

Shavi GR, Thakur B, Bhambal A, Jain S, Singh V, Shukla A - J Int Oral Health (2015)

Percentage distribution of domains and single itemsaccording to mean value.
© Copyright Policy - open-access
Related In: Results  -  Collection

License
Show All Figures
getmorefigures.php?uid=PMC4588784&req=5

Figure 1: Percentage distribution of domains and single itemsaccording to mean value.
Mentions: The study population consisted of 153 patients diagnosed with HNC and receiving treatment. Patients’ characteristics for the whole study group are shown in Tables 1 and 2. Among the cancer patient’s males comprised the majority of the study population i.e., 120 (78.4%). 84 (54.9%) belonged to 41 and 60 years age group. Most of them were married (148, 96.7%), the majority of subjects belonged to upper lower class 55 (35.9%) (Table 1). 95 (62.1%) HNC patients had smokeless tobacco and majority of duration of tobacco chewing 69 (45.1%) were more than 15 years. For ease of analysis we divided site of cancer into four categories. Buccal mucosa, tongue, alveolus, maxilla, mandible, gingivo buccal sulcus and pyrifossa were clubbed into a single category i.e., oral cavity. The remaining three categories were oropharynx, hypopharynx and larynx respectively. majority of cancers originated in oral cavity i.e., 118 (77.12%). At the time of study 83 (54.2%) population presented with Stage II cancer and majority of the patients 88 (57.6%) were diagnosed within 6 months. The most administered form of treatment was radiation + surgery therapy 39 (25.5%) followed by radiation therapy 38 (24.8%). The QLQ-H&N35 specific questionnaire, Graph 1 shows the mean value of all the domains and single items. High mean score shows worst symptoms response. So, according to mean value the main factors affecting QoL were lost weight (79.08), taking painkiller (75.82), sticky saliva (72.75), reduced mouth opening (68.17) and difficulty in social eating (69.10). The scales and single items of QoL questionnaire were compared according to sites of tumor, stage of cancer, type of treatment method. Table 3 shows patients with small tumors (Stage I+II) scored better than those with large tumors (Stage III+IV). Patients with large tumor (Stage III+IV) had worst value for swallowing (P = 0.00), speech (P = 0.00), social eating (P = 0.00), social contact (P = 0.001), reduced mouth opening (P = 0.00), dry mouth (P = 0.001), cough problem (P = 0.00) feeling of being ill (P = 0.00) and use of feeding tube (P = 0.050).

Bottom Line: Main factors affecting QoL were loss of weight, use of painkillers, sticky saliva, reduced mouth opening and problems in social eating.Significant association found between pain (P = 0.044), swallowing (P = 0.018), sense (P = 0.001), Social eating (P = 0.003), social contact (P = 0.008), reduced mouth opening (P = 0.008) with respect to type of treatment.We conclude that there was a significant reduction in the QoL in cancer patients resulting from myriad forms of cancers.

View Article: PubMed Central - PubMed

Affiliation: Professor & Head, Department of Public Health Dentistry, Rajasthan Dental College and Hospital, Jaipur, Rajasthan, India.

ABSTRACT

Background: To assess the oral health related quality of life (OHRQoL) of head and neck cancer patients and to find association between QoL, demographic and disease variables.

Methods: This cross-sectional study was conducted on 153 patients diagnosed and being treated for head and neck cancer in Jawaharlal Nehru Cancer Hospital, India. Data collected from the survey included demographic details and OHRQoL, which was measured by European Organization of Research for Treatment of Cancer QoL questionnaire head & neck-35. Cancer measurements (location of tumor, stages of cancer, treatment type) were collected from the patient's hospital records.

Results: The majority of the population 84 (54.9%) belonged to 41-60 years age group and most of them were male (78.4%). The most frequent site of the primary tumor was the oral cavity (71.3%) and the majority of patients had Stage II and III cancer. Main factors affecting QoL were loss of weight, use of painkillers, sticky saliva, reduced mouth opening and problems in social eating. Significant association found between pain (P = 0.044), swallowing (P = 0.018), sense (P = 0.001), Social eating (P = 0.003), social contact (P = 0.008), reduced mouth opening (P = 0.008) with respect to type of treatment.

Conclusions: We conclude that there was a significant reduction in the QoL in cancer patients resulting from myriad forms of cancers. An assessment of the QoL and symptoms can help the dentist to direct attention to most important symptoms and provide counseling for appropriate interventions towards improving QoL outcomes and the response to the treatment.

No MeSH data available.


Related in: MedlinePlus