Type and amount of dietary protein in the treatment of metabolic syndrome: a randomized controlled trial.
Bottom Line: Diets were compared across 3 phases of energy balance: 5 wk of controlled (all foods provided) weight maintenance (WM), 6 wk of controlled weight loss (minimum 500-kcal/d deficit) including exercise (WL), and 12 wk of prescribed, free-living weight loss (FL).After WM, all groups had a MetS prevalence of 80-90% [healthy American diet (HAD) compared with WM, P = NS], which decreased to 50-60% after WL and was maintained through FL (HAD, WM vs WL, FL, P < 0.01).Weight loss was the primary modifier of MetS resolution in our study population regardless of protein source or amount.
Affiliation: School of Pharmacy & Medical Sciences, University of South Australia, Adelaide, Australia; and Department of Nutritional Sciences and.Show MeSH
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Mentions: Daily compliance records for the controlled-feeding HAD phase indicated that there was total dietary compliance on 74% ± 2%, 81% ± 3%, and 84% ± 1% of reported study days for the BOLD, BOLD+ and M-DASH groups, respectively. During the WM phase (when participants were consuming the experimental diets), participants in the BOLD, BOLD+, and M-DASH groups reported being compliant on 70% ± 1%, 77% ± 1%, and 82% ± 1% of study days, respectively. Compliance during the WL phase was 75% ± 1%, 80% ± 1%, and 90% ± 1% for the BOLD, BOLD+, and M-DASH groups, respectively. Weight changes corresponding to the varying energy levels (i.e., WM or WL) during the controlled-feeding diet phases demonstrate an overall high amount of compliance to the study protocol during the controlled-feeding phases (see Weight and body composition, Figure 2). Participants did not achieve further weight loss during the FL phase; body weight losses were maintained during this phase.
Affiliation: School of Pharmacy & Medical Sciences, University of South Australia, Adelaide, Australia; and Department of Nutritional Sciences and.