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Construction of Zinc Oxide into Different Morphological Structures to Be Utilized as Antimicrobial Agent against Multidrug Resistant Bacteria.

Elkady MF, Shokry Hassan H, Hafez EE, Fouad A - Bioinorg Chem Appl (2015)

Bottom Line: Nano-ZnO has been successfully implemented in particles, rods, and tubes nanostructures via sol-gel and hydrothermal techniques.The activity of produced nano-ZnO was determined by disc diffusion technique and the results revealed that ZnO nanotubes recorded high activity against the studied strains due to their high surface area equivalent to 17.8 m(2)/g.Although the annealing process of ZnO improves the degree of material crystallinity, however, it declines its surface area and consequently its antimicrobial activity.

View Article: PubMed Central - PubMed

Affiliation: Fabrication Technology Department, Advanced Technology and New Materials Research Institute (ATNMRI), City of Scientific Research and Technological Applications, Alexandria 21934, Egypt ; Chemical and Petrochemical Engineering Department, Egypt-Japan University of Science and Technology, New Borg El-Arab City, Alexandria 21934, Egypt.

ABSTRACT
Nano-ZnO has been successfully implemented in particles, rods, and tubes nanostructures via sol-gel and hydrothermal techniques. The variation of the different preparation parameters such as reaction temperature, time, and stabilizer agents was optimized to attain different morphological structures. The influence of the microwave annealing process on ZnO crystallinity, surface area, and morphological structure was monitored using XRD, BET, and SEM techniques, respectively. The antimicrobial activity of zinc oxide produced in nanotubes structure was examined against four different multidrug resistant bacteria: Gram-positive (Staphylococcus aureus and Bacillus subtilis) and Gram-negative (Escherichia coli and Pseudomonas aeruginosa) strains. The activity of produced nano-ZnO was determined by disc diffusion technique and the results revealed that ZnO nanotubes recorded high activity against the studied strains due to their high surface area equivalent to 17.8 m(2)/g. The minimum inhibitory concentration (MIC) of ZnO nanotubes showed that the low concentrations of ZnO nanotubes could be a substitution for the commercial antibiotics when approached in suitable formula. Although the annealing process of ZnO improves the degree of material crystallinity, however, it declines its surface area and consequently its antimicrobial activity.

No MeSH data available.


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SEM micrographs of ZnO prepared using sol-gel technique at different reaction temperatures: (a) 60°C, (b) 70°C, (c) 80°C, and (d) 90°C.
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fig6: SEM micrographs of ZnO prepared using sol-gel technique at different reaction temperatures: (a) 60°C, (b) 70°C, (c) 80°C, and (d) 90°C.

Mentions: (ii) Morphological Structure (SEM). The most proper selected surfactant (PVP) at different reaction temperatures (60, 70, 80, and 90°C) was tested for production of different zinc oxide configurations. Figure 6 indicated that ZnO formed at either 60 or 80°C has nanoparticles configuration with average diameters ranging between 25 and 57 nm. However, those produced at 70°C have nanorods morphologies with average aspect ratio of 4. Also, nanoplates of ZnO have been produced at 90°C. This behavior may be attributed to the fact that the growth kinetic process of ZnO is slow at low temperatures, so the growth of nanospecies takes place at higher temperature to obtain different morphological structures. However, rise in reaction temperature results in increase in reaction rate, so ZnO grains rapidly grow, which leads to formation of nanorods with random orientations at 70°C. Also at higher temperature breaking rate of complexed metal ions releases more metal ions for rapid nucleation and growth process. The morphology evolution of ZnO as influence of temperature is due to nanorods getting squeezed together to form nanoparticles [33]. So, the most preferred temperature for production of uniform zinc oxide nanorods is 70°C. So, the reaction temperature has determinative effects on nano-zinc oxide formation [34].


Construction of Zinc Oxide into Different Morphological Structures to Be Utilized as Antimicrobial Agent against Multidrug Resistant Bacteria.

Elkady MF, Shokry Hassan H, Hafez EE, Fouad A - Bioinorg Chem Appl (2015)

SEM micrographs of ZnO prepared using sol-gel technique at different reaction temperatures: (a) 60°C, (b) 70°C, (c) 80°C, and (d) 90°C.
© Copyright Policy - open-access
Related In: Results  -  Collection

Show All Figures
getmorefigures.php?uid=PMC4588359&req=5

fig6: SEM micrographs of ZnO prepared using sol-gel technique at different reaction temperatures: (a) 60°C, (b) 70°C, (c) 80°C, and (d) 90°C.
Mentions: (ii) Morphological Structure (SEM). The most proper selected surfactant (PVP) at different reaction temperatures (60, 70, 80, and 90°C) was tested for production of different zinc oxide configurations. Figure 6 indicated that ZnO formed at either 60 or 80°C has nanoparticles configuration with average diameters ranging between 25 and 57 nm. However, those produced at 70°C have nanorods morphologies with average aspect ratio of 4. Also, nanoplates of ZnO have been produced at 90°C. This behavior may be attributed to the fact that the growth kinetic process of ZnO is slow at low temperatures, so the growth of nanospecies takes place at higher temperature to obtain different morphological structures. However, rise in reaction temperature results in increase in reaction rate, so ZnO grains rapidly grow, which leads to formation of nanorods with random orientations at 70°C. Also at higher temperature breaking rate of complexed metal ions releases more metal ions for rapid nucleation and growth process. The morphology evolution of ZnO as influence of temperature is due to nanorods getting squeezed together to form nanoparticles [33]. So, the most preferred temperature for production of uniform zinc oxide nanorods is 70°C. So, the reaction temperature has determinative effects on nano-zinc oxide formation [34].

Bottom Line: Nano-ZnO has been successfully implemented in particles, rods, and tubes nanostructures via sol-gel and hydrothermal techniques.The activity of produced nano-ZnO was determined by disc diffusion technique and the results revealed that ZnO nanotubes recorded high activity against the studied strains due to their high surface area equivalent to 17.8 m(2)/g.Although the annealing process of ZnO improves the degree of material crystallinity, however, it declines its surface area and consequently its antimicrobial activity.

View Article: PubMed Central - PubMed

Affiliation: Fabrication Technology Department, Advanced Technology and New Materials Research Institute (ATNMRI), City of Scientific Research and Technological Applications, Alexandria 21934, Egypt ; Chemical and Petrochemical Engineering Department, Egypt-Japan University of Science and Technology, New Borg El-Arab City, Alexandria 21934, Egypt.

ABSTRACT
Nano-ZnO has been successfully implemented in particles, rods, and tubes nanostructures via sol-gel and hydrothermal techniques. The variation of the different preparation parameters such as reaction temperature, time, and stabilizer agents was optimized to attain different morphological structures. The influence of the microwave annealing process on ZnO crystallinity, surface area, and morphological structure was monitored using XRD, BET, and SEM techniques, respectively. The antimicrobial activity of zinc oxide produced in nanotubes structure was examined against four different multidrug resistant bacteria: Gram-positive (Staphylococcus aureus and Bacillus subtilis) and Gram-negative (Escherichia coli and Pseudomonas aeruginosa) strains. The activity of produced nano-ZnO was determined by disc diffusion technique and the results revealed that ZnO nanotubes recorded high activity against the studied strains due to their high surface area equivalent to 17.8 m(2)/g. The minimum inhibitory concentration (MIC) of ZnO nanotubes showed that the low concentrations of ZnO nanotubes could be a substitution for the commercial antibiotics when approached in suitable formula. Although the annealing process of ZnO improves the degree of material crystallinity, however, it declines its surface area and consequently its antimicrobial activity.

No MeSH data available.


Related in: MedlinePlus