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Brain lateralization and self-reported symptoms of ADHD in a population sample of adults: a dimensional approach.

Mohamed SM, Börger NA, Geuze RH, van der Meere JJ - Front Psychol (2015)

Bottom Line: For both task conditions, brain lateralization was indexed as the difference in mean reaction time between left and right visual field.These findings from a population sample of adults do not support the dimensionality of lateralized information processing deficit in ADHD symptomatology.However, group comparison analyses showed that subjects with high level of inattention symptoms close to or above the clinical cut-off had a reduced right hemisphere processing in the Shape Physical-Identity condition.

View Article: PubMed Central - PubMed

Affiliation: Department of Clinical and Developmental Neuropsychology, Faculty of Behavioural and Social Sciences, University of Groningen Groningen, Netherlands ; Department of Psychology, Beni-Suef University Beni-Suef, Egypt.

ABSTRACT
Many clinical studies reported a compromised brain lateralization in patients with Attention-Deficit/Hyperactivity Disorder (ADHD) without being conclusive about whether the deficit existed in the left or right hemisphere. It is well-recognized that studying ADHD dimensionally is more controlled for comorbid problems and medication effects, and provides more accurate assessment of the symptoms. Therefore, the present study applied the dimensional approach to test the relationship between brain lateralization and self-reported ADHD symptoms in a population sample. Eighty-five right-handed university students filled in the Conners' Adult ADHD Rating Scales and performed a lateralization reaction time task. The task consists of two matching conditions: one condition requires nominal identification for letters tapping left hemisphere specialization (Letter Name-Identity condition) and the other one requires physical and visuospatial identification for shapes tapping right hemisphere specialization (Shape Physical-Identity condition). The letters or shapes to be matched are presented in left or right visual field of a fixation cross. For both task conditions, brain lateralization was indexed as the difference in mean reaction time between left and right visual field. Linear regression analyses, controlled for mood symptoms reported by a depression, anxiety, and stress scale, showed no relationship between the variables. These findings from a population sample of adults do not support the dimensionality of lateralized information processing deficit in ADHD symptomatology. However, group comparison analyses showed that subjects with high level of inattention symptoms close to or above the clinical cut-off had a reduced right hemisphere processing in the Shape Physical-Identity condition.

No MeSH data available.


Related in: MedlinePlus

Visual field advantage in the groups with High- and Low-score on inattention subscale. Error bars indicate standard errors.
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Figure 5: Visual field advantage in the groups with High- and Low-score on inattention subscale. Error bars indicate standard errors.

Mentions: Comparing participants in the first and fourth quartile scores on inattention, hyperactivity and impulsivity yielded a significant difference in the size of visual filed advantage for group composition based on inattention. The High-score group (n = 23) on the inattention subscale showed a significant lower LVF/right hemisphere advantage than the Low-score group (n = 28); the main effect of group was significant F(1,49) = 5.97, p < 0.02, = 0.11. Post hoc analysis for the inattention subscale indicated that group differences were in the Shape Physical-Identity condition, t(49) = 2.38, p = 0.02, but not in the Letter Name-Identity condition, the mean size of visual field advantage were 6.27 and 12.03 in the Letter Name-Identity condition, and were 7.56 and 17.40 in the Shape Physical-Identity condition for, respectively, the High- and the Low-score group (see Figure 5). Groups did not differ on the other scales in the two task conditions.


Brain lateralization and self-reported symptoms of ADHD in a population sample of adults: a dimensional approach.

Mohamed SM, Börger NA, Geuze RH, van der Meere JJ - Front Psychol (2015)

Visual field advantage in the groups with High- and Low-score on inattention subscale. Error bars indicate standard errors.
© Copyright Policy
Related In: Results  -  Collection

License
Show All Figures
getmorefigures.php?uid=PMC4585266&req=5

Figure 5: Visual field advantage in the groups with High- and Low-score on inattention subscale. Error bars indicate standard errors.
Mentions: Comparing participants in the first and fourth quartile scores on inattention, hyperactivity and impulsivity yielded a significant difference in the size of visual filed advantage for group composition based on inattention. The High-score group (n = 23) on the inattention subscale showed a significant lower LVF/right hemisphere advantage than the Low-score group (n = 28); the main effect of group was significant F(1,49) = 5.97, p < 0.02, = 0.11. Post hoc analysis for the inattention subscale indicated that group differences were in the Shape Physical-Identity condition, t(49) = 2.38, p = 0.02, but not in the Letter Name-Identity condition, the mean size of visual field advantage were 6.27 and 12.03 in the Letter Name-Identity condition, and were 7.56 and 17.40 in the Shape Physical-Identity condition for, respectively, the High- and the Low-score group (see Figure 5). Groups did not differ on the other scales in the two task conditions.

Bottom Line: For both task conditions, brain lateralization was indexed as the difference in mean reaction time between left and right visual field.These findings from a population sample of adults do not support the dimensionality of lateralized information processing deficit in ADHD symptomatology.However, group comparison analyses showed that subjects with high level of inattention symptoms close to or above the clinical cut-off had a reduced right hemisphere processing in the Shape Physical-Identity condition.

View Article: PubMed Central - PubMed

Affiliation: Department of Clinical and Developmental Neuropsychology, Faculty of Behavioural and Social Sciences, University of Groningen Groningen, Netherlands ; Department of Psychology, Beni-Suef University Beni-Suef, Egypt.

ABSTRACT
Many clinical studies reported a compromised brain lateralization in patients with Attention-Deficit/Hyperactivity Disorder (ADHD) without being conclusive about whether the deficit existed in the left or right hemisphere. It is well-recognized that studying ADHD dimensionally is more controlled for comorbid problems and medication effects, and provides more accurate assessment of the symptoms. Therefore, the present study applied the dimensional approach to test the relationship between brain lateralization and self-reported ADHD symptoms in a population sample. Eighty-five right-handed university students filled in the Conners' Adult ADHD Rating Scales and performed a lateralization reaction time task. The task consists of two matching conditions: one condition requires nominal identification for letters tapping left hemisphere specialization (Letter Name-Identity condition) and the other one requires physical and visuospatial identification for shapes tapping right hemisphere specialization (Shape Physical-Identity condition). The letters or shapes to be matched are presented in left or right visual field of a fixation cross. For both task conditions, brain lateralization was indexed as the difference in mean reaction time between left and right visual field. Linear regression analyses, controlled for mood symptoms reported by a depression, anxiety, and stress scale, showed no relationship between the variables. These findings from a population sample of adults do not support the dimensionality of lateralized information processing deficit in ADHD symptomatology. However, group comparison analyses showed that subjects with high level of inattention symptoms close to or above the clinical cut-off had a reduced right hemisphere processing in the Shape Physical-Identity condition.

No MeSH data available.


Related in: MedlinePlus