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Brain lateralization and self-reported symptoms of ADHD in a population sample of adults: a dimensional approach.

Mohamed SM, Börger NA, Geuze RH, van der Meere JJ - Front Psychol (2015)

Bottom Line: For both task conditions, brain lateralization was indexed as the difference in mean reaction time between left and right visual field.These findings from a population sample of adults do not support the dimensionality of lateralized information processing deficit in ADHD symptomatology.However, group comparison analyses showed that subjects with high level of inattention symptoms close to or above the clinical cut-off had a reduced right hemisphere processing in the Shape Physical-Identity condition.

View Article: PubMed Central - PubMed

Affiliation: Department of Clinical and Developmental Neuropsychology, Faculty of Behavioural and Social Sciences, University of Groningen Groningen, Netherlands ; Department of Psychology, Beni-Suef University Beni-Suef, Egypt.

ABSTRACT
Many clinical studies reported a compromised brain lateralization in patients with Attention-Deficit/Hyperactivity Disorder (ADHD) without being conclusive about whether the deficit existed in the left or right hemisphere. It is well-recognized that studying ADHD dimensionally is more controlled for comorbid problems and medication effects, and provides more accurate assessment of the symptoms. Therefore, the present study applied the dimensional approach to test the relationship between brain lateralization and self-reported ADHD symptoms in a population sample. Eighty-five right-handed university students filled in the Conners' Adult ADHD Rating Scales and performed a lateralization reaction time task. The task consists of two matching conditions: one condition requires nominal identification for letters tapping left hemisphere specialization (Letter Name-Identity condition) and the other one requires physical and visuospatial identification for shapes tapping right hemisphere specialization (Shape Physical-Identity condition). The letters or shapes to be matched are presented in left or right visual field of a fixation cross. For both task conditions, brain lateralization was indexed as the difference in mean reaction time between left and right visual field. Linear regression analyses, controlled for mood symptoms reported by a depression, anxiety, and stress scale, showed no relationship between the variables. These findings from a population sample of adults do not support the dimensionality of lateralized information processing deficit in ADHD symptomatology. However, group comparison analyses showed that subjects with high level of inattention symptoms close to or above the clinical cut-off had a reduced right hemisphere processing in the Shape Physical-Identity condition.

No MeSH data available.


Related in: MedlinePlus

Five shapes and their mirror shapes, each consists of three small connected lines of 2 mm long and line thickness of 2.25 point size.
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Figure 2: Five shapes and their mirror shapes, each consists of three small connected lines of 2 mm long and line thickness of 2.25 point size.

Mentions: There were two matching conditions; in the first the Letter Name-Identity condition, letters were displayed in different cases (the probes in upper-case and the target in lower-case) and randomly chosen from the letters A, B, D, G, H, E, F, L, R, M, T, and Q. A match was defined when one of the probes and the target had same name identity regardless of the letter case. The match may rely on the phonetic code of the letter names tapping left hemisphere processing. In the second condition, Shape Physical-Identity, unfamiliar shapes (the probes as well as the target) were displayed in their original form or in their mirrored form (see Figure 2). A match was defined when one of the probes matched the target in the shape and orientation.


Brain lateralization and self-reported symptoms of ADHD in a population sample of adults: a dimensional approach.

Mohamed SM, Börger NA, Geuze RH, van der Meere JJ - Front Psychol (2015)

Five shapes and their mirror shapes, each consists of three small connected lines of 2 mm long and line thickness of 2.25 point size.
© Copyright Policy
Related In: Results  -  Collection

License
Show All Figures
getmorefigures.php?uid=PMC4585266&req=5

Figure 2: Five shapes and their mirror shapes, each consists of three small connected lines of 2 mm long and line thickness of 2.25 point size.
Mentions: There were two matching conditions; in the first the Letter Name-Identity condition, letters were displayed in different cases (the probes in upper-case and the target in lower-case) and randomly chosen from the letters A, B, D, G, H, E, F, L, R, M, T, and Q. A match was defined when one of the probes and the target had same name identity regardless of the letter case. The match may rely on the phonetic code of the letter names tapping left hemisphere processing. In the second condition, Shape Physical-Identity, unfamiliar shapes (the probes as well as the target) were displayed in their original form or in their mirrored form (see Figure 2). A match was defined when one of the probes matched the target in the shape and orientation.

Bottom Line: For both task conditions, brain lateralization was indexed as the difference in mean reaction time between left and right visual field.These findings from a population sample of adults do not support the dimensionality of lateralized information processing deficit in ADHD symptomatology.However, group comparison analyses showed that subjects with high level of inattention symptoms close to or above the clinical cut-off had a reduced right hemisphere processing in the Shape Physical-Identity condition.

View Article: PubMed Central - PubMed

Affiliation: Department of Clinical and Developmental Neuropsychology, Faculty of Behavioural and Social Sciences, University of Groningen Groningen, Netherlands ; Department of Psychology, Beni-Suef University Beni-Suef, Egypt.

ABSTRACT
Many clinical studies reported a compromised brain lateralization in patients with Attention-Deficit/Hyperactivity Disorder (ADHD) without being conclusive about whether the deficit existed in the left or right hemisphere. It is well-recognized that studying ADHD dimensionally is more controlled for comorbid problems and medication effects, and provides more accurate assessment of the symptoms. Therefore, the present study applied the dimensional approach to test the relationship between brain lateralization and self-reported ADHD symptoms in a population sample. Eighty-five right-handed university students filled in the Conners' Adult ADHD Rating Scales and performed a lateralization reaction time task. The task consists of two matching conditions: one condition requires nominal identification for letters tapping left hemisphere specialization (Letter Name-Identity condition) and the other one requires physical and visuospatial identification for shapes tapping right hemisphere specialization (Shape Physical-Identity condition). The letters or shapes to be matched are presented in left or right visual field of a fixation cross. For both task conditions, brain lateralization was indexed as the difference in mean reaction time between left and right visual field. Linear regression analyses, controlled for mood symptoms reported by a depression, anxiety, and stress scale, showed no relationship between the variables. These findings from a population sample of adults do not support the dimensionality of lateralized information processing deficit in ADHD symptomatology. However, group comparison analyses showed that subjects with high level of inattention symptoms close to or above the clinical cut-off had a reduced right hemisphere processing in the Shape Physical-Identity condition.

No MeSH data available.


Related in: MedlinePlus