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Brain lateralization and self-reported symptoms of ADHD in a population sample of adults: a dimensional approach.

Mohamed SM, Börger NA, Geuze RH, van der Meere JJ - Front Psychol (2015)

Bottom Line: For both task conditions, brain lateralization was indexed as the difference in mean reaction time between left and right visual field.These findings from a population sample of adults do not support the dimensionality of lateralized information processing deficit in ADHD symptomatology.However, group comparison analyses showed that subjects with high level of inattention symptoms close to or above the clinical cut-off had a reduced right hemisphere processing in the Shape Physical-Identity condition.

View Article: PubMed Central - PubMed

Affiliation: Department of Clinical and Developmental Neuropsychology, Faculty of Behavioural and Social Sciences, University of Groningen Groningen, Netherlands ; Department of Psychology, Beni-Suef University Beni-Suef, Egypt.

ABSTRACT
Many clinical studies reported a compromised brain lateralization in patients with Attention-Deficit/Hyperactivity Disorder (ADHD) without being conclusive about whether the deficit existed in the left or right hemisphere. It is well-recognized that studying ADHD dimensionally is more controlled for comorbid problems and medication effects, and provides more accurate assessment of the symptoms. Therefore, the present study applied the dimensional approach to test the relationship between brain lateralization and self-reported ADHD symptoms in a population sample. Eighty-five right-handed university students filled in the Conners' Adult ADHD Rating Scales and performed a lateralization reaction time task. The task consists of two matching conditions: one condition requires nominal identification for letters tapping left hemisphere specialization (Letter Name-Identity condition) and the other one requires physical and visuospatial identification for shapes tapping right hemisphere specialization (Shape Physical-Identity condition). The letters or shapes to be matched are presented in left or right visual field of a fixation cross. For both task conditions, brain lateralization was indexed as the difference in mean reaction time between left and right visual field. Linear regression analyses, controlled for mood symptoms reported by a depression, anxiety, and stress scale, showed no relationship between the variables. These findings from a population sample of adults do not support the dimensionality of lateralized information processing deficit in ADHD symptomatology. However, group comparison analyses showed that subjects with high level of inattention symptoms close to or above the clinical cut-off had a reduced right hemisphere processing in the Shape Physical-Identity condition.

No MeSH data available.


Related in: MedlinePlus

Examples of match stimuli in the left and right visual field for the task conditions. LVF = left visual field; RVF = right visual field.
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Figure 1: Examples of match stimuli in the left and right visual field for the task conditions. LVF = left visual field; RVF = right visual field.

Mentions: The task was based on the Banich paradigm (Banich, 1998). The stimuli consist of a fixation cross and three letters or shapes arranged at the vertices of an invisible triangle. Two of the letters or shapes were presented above the fixation cross while the third was presented below (see Figure 1). The two letters or shapes above the fixation cross were the probes, and the letter or shape below the fixation cross was the target. One of the two probes had to be matched with the target. When a match is detected the subject has to press a response button.


Brain lateralization and self-reported symptoms of ADHD in a population sample of adults: a dimensional approach.

Mohamed SM, Börger NA, Geuze RH, van der Meere JJ - Front Psychol (2015)

Examples of match stimuli in the left and right visual field for the task conditions. LVF = left visual field; RVF = right visual field.
© Copyright Policy
Related In: Results  -  Collection

License
Show All Figures
getmorefigures.php?uid=PMC4585266&req=5

Figure 1: Examples of match stimuli in the left and right visual field for the task conditions. LVF = left visual field; RVF = right visual field.
Mentions: The task was based on the Banich paradigm (Banich, 1998). The stimuli consist of a fixation cross and three letters or shapes arranged at the vertices of an invisible triangle. Two of the letters or shapes were presented above the fixation cross while the third was presented below (see Figure 1). The two letters or shapes above the fixation cross were the probes, and the letter or shape below the fixation cross was the target. One of the two probes had to be matched with the target. When a match is detected the subject has to press a response button.

Bottom Line: For both task conditions, brain lateralization was indexed as the difference in mean reaction time between left and right visual field.These findings from a population sample of adults do not support the dimensionality of lateralized information processing deficit in ADHD symptomatology.However, group comparison analyses showed that subjects with high level of inattention symptoms close to or above the clinical cut-off had a reduced right hemisphere processing in the Shape Physical-Identity condition.

View Article: PubMed Central - PubMed

Affiliation: Department of Clinical and Developmental Neuropsychology, Faculty of Behavioural and Social Sciences, University of Groningen Groningen, Netherlands ; Department of Psychology, Beni-Suef University Beni-Suef, Egypt.

ABSTRACT
Many clinical studies reported a compromised brain lateralization in patients with Attention-Deficit/Hyperactivity Disorder (ADHD) without being conclusive about whether the deficit existed in the left or right hemisphere. It is well-recognized that studying ADHD dimensionally is more controlled for comorbid problems and medication effects, and provides more accurate assessment of the symptoms. Therefore, the present study applied the dimensional approach to test the relationship between brain lateralization and self-reported ADHD symptoms in a population sample. Eighty-five right-handed university students filled in the Conners' Adult ADHD Rating Scales and performed a lateralization reaction time task. The task consists of two matching conditions: one condition requires nominal identification for letters tapping left hemisphere specialization (Letter Name-Identity condition) and the other one requires physical and visuospatial identification for shapes tapping right hemisphere specialization (Shape Physical-Identity condition). The letters or shapes to be matched are presented in left or right visual field of a fixation cross. For both task conditions, brain lateralization was indexed as the difference in mean reaction time between left and right visual field. Linear regression analyses, controlled for mood symptoms reported by a depression, anxiety, and stress scale, showed no relationship between the variables. These findings from a population sample of adults do not support the dimensionality of lateralized information processing deficit in ADHD symptomatology. However, group comparison analyses showed that subjects with high level of inattention symptoms close to or above the clinical cut-off had a reduced right hemisphere processing in the Shape Physical-Identity condition.

No MeSH data available.


Related in: MedlinePlus