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Framing effects reveal discrete lexical-semantic and sublexical procedures in reading: an fMRI study.

Danelli L, Marelli M, Berlingeri M, Tettamanti M, Sberna M, Paulesu E, Luzzatti C - Front Psychol (2015)

Bottom Line: Although meta-analyses of the imaging literature support the existence of distinct but interacting reading procedures, individual neuroimaging studies that explored neural correlates of reading yielded inconclusive results.At the behavioral level, we found sizeable effects of the framing manipulations that included slower voice onset times for stimuli in the pseudoword frames.These patterns of activation represented a valid classifying model of fMRI images associated with target reading in both frames in the multi-voxel pattern analyses.

View Article: PubMed Central - PubMed

Affiliation: Psychology Department, University of Milan-Bicocca Milan, Italy ; NeuroMI -Milan Center for Neuroscience Milan, Italy.

ABSTRACT
According to the dual-route model, a printed string of letters can be processed by either a grapheme-to-phoneme conversion (GPC) route or a lexical-semantic route. Although meta-analyses of the imaging literature support the existence of distinct but interacting reading procedures, individual neuroimaging studies that explored neural correlates of reading yielded inconclusive results. We used a list-manipulation paradigm to provide a fresh empirical look at this issue and to isolate specific areas that underlie the two reading procedures. In a lexical condition, we embedded disyllabic Italian words (target stimuli) in lists of either loanwords or trisyllabic Italian words with unpredictable stress position. In a GPC condition, similar target stimuli were included within lists of pseudowords. The procedure was designed to induce participants to emphasize either the lexical-semantic or the GPC reading procedure, while controlling for possible linguistic confounds and keeping the reading task requirements stable across the two conditions. Thirty-three adults participated in the behavioral study, and 20 further adult participants were included in the fMRI study. At the behavioral level, we found sizeable effects of the framing manipulations that included slower voice onset times for stimuli in the pseudoword frames. At the functional anatomical level, the occipital and temporal regions, and the intraparietal sulcus were specifically activated when subjects were reading target words in a lexical frame. The inferior parietal and anterior fusiform cortex were specifically activated in the GPC condition. These patterns of activation represented a valid classifying model of fMRI images associated with target reading in both frames in the multi-voxel pattern analyses. Further activations were shared by the two procedures in the occipital and inferior parietal areas, in the premotor cortex, in the frontal regions and the left supplementary motor area. These regions are most likely involved in either early input or late output processes.

No MeSH data available.


Brain activation data. The cerebral areas that are specifically associated with lexical processing (in blue), sublexical processing (in yellow), and with both reading procedures (in red) are displayed on an anatomical template image (the “ch2better” template image in MRICron; Rorden and Brett, 2000).
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Figure 2: Brain activation data. The cerebral areas that are specifically associated with lexical processing (in blue), sublexical processing (in yellow), and with both reading procedures (in red) are displayed on an anatomical template image (the “ch2better” template image in MRICron; Rorden and Brett, 2000).

Mentions: A significant activation was found in the left supplementary motor area (SMA), in the left middle frontal gyrus, in the inferior frontal gyrus, bilaterally, in the left precentral and postcentral gyri, in the left superior parietal lobule, in the left intraparietal sulcus, in the superior temporal pole, bilaterally, in the left superior temporal gyrus, in the middle temporal gyrus, bilaterally, in the left hippocampus, in the left fusiform gyrus, in the left middle occipital gyrus, in the inferior occipital gyrus, bilaterally, in the left V1, in the left lingual gyrus and in the cerebellum, bilaterally (Table 2A and areas in blue in Figure 2).


Framing effects reveal discrete lexical-semantic and sublexical procedures in reading: an fMRI study.

Danelli L, Marelli M, Berlingeri M, Tettamanti M, Sberna M, Paulesu E, Luzzatti C - Front Psychol (2015)

Brain activation data. The cerebral areas that are specifically associated with lexical processing (in blue), sublexical processing (in yellow), and with both reading procedures (in red) are displayed on an anatomical template image (the “ch2better” template image in MRICron; Rorden and Brett, 2000).
© Copyright Policy
Related In: Results  -  Collection

License
Show All Figures
getmorefigures.php?uid=PMC4585139&req=5

Figure 2: Brain activation data. The cerebral areas that are specifically associated with lexical processing (in blue), sublexical processing (in yellow), and with both reading procedures (in red) are displayed on an anatomical template image (the “ch2better” template image in MRICron; Rorden and Brett, 2000).
Mentions: A significant activation was found in the left supplementary motor area (SMA), in the left middle frontal gyrus, in the inferior frontal gyrus, bilaterally, in the left precentral and postcentral gyri, in the left superior parietal lobule, in the left intraparietal sulcus, in the superior temporal pole, bilaterally, in the left superior temporal gyrus, in the middle temporal gyrus, bilaterally, in the left hippocampus, in the left fusiform gyrus, in the left middle occipital gyrus, in the inferior occipital gyrus, bilaterally, in the left V1, in the left lingual gyrus and in the cerebellum, bilaterally (Table 2A and areas in blue in Figure 2).

Bottom Line: Although meta-analyses of the imaging literature support the existence of distinct but interacting reading procedures, individual neuroimaging studies that explored neural correlates of reading yielded inconclusive results.At the behavioral level, we found sizeable effects of the framing manipulations that included slower voice onset times for stimuli in the pseudoword frames.These patterns of activation represented a valid classifying model of fMRI images associated with target reading in both frames in the multi-voxel pattern analyses.

View Article: PubMed Central - PubMed

Affiliation: Psychology Department, University of Milan-Bicocca Milan, Italy ; NeuroMI -Milan Center for Neuroscience Milan, Italy.

ABSTRACT
According to the dual-route model, a printed string of letters can be processed by either a grapheme-to-phoneme conversion (GPC) route or a lexical-semantic route. Although meta-analyses of the imaging literature support the existence of distinct but interacting reading procedures, individual neuroimaging studies that explored neural correlates of reading yielded inconclusive results. We used a list-manipulation paradigm to provide a fresh empirical look at this issue and to isolate specific areas that underlie the two reading procedures. In a lexical condition, we embedded disyllabic Italian words (target stimuli) in lists of either loanwords or trisyllabic Italian words with unpredictable stress position. In a GPC condition, similar target stimuli were included within lists of pseudowords. The procedure was designed to induce participants to emphasize either the lexical-semantic or the GPC reading procedure, while controlling for possible linguistic confounds and keeping the reading task requirements stable across the two conditions. Thirty-three adults participated in the behavioral study, and 20 further adult participants were included in the fMRI study. At the behavioral level, we found sizeable effects of the framing manipulations that included slower voice onset times for stimuli in the pseudoword frames. At the functional anatomical level, the occipital and temporal regions, and the intraparietal sulcus were specifically activated when subjects were reading target words in a lexical frame. The inferior parietal and anterior fusiform cortex were specifically activated in the GPC condition. These patterns of activation represented a valid classifying model of fMRI images associated with target reading in both frames in the multi-voxel pattern analyses. Further activations were shared by the two procedures in the occipital and inferior parietal areas, in the premotor cortex, in the frontal regions and the left supplementary motor area. These regions are most likely involved in either early input or late output processes.

No MeSH data available.