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Organogel-nanoemulsion containing nisin and D-limonene and its antimicrobial activity.

Bei W, Zhou Y, Xing X, Zahi MR, Li Y, Yuan Q, Liang H - Front Microbiol (2015)

Bottom Line: The aim of this study was to investigate a novel delivery system containing D-limonene and nisin by food organogel-nanoemulsion and study its effect on the antimicrobial activity.The average droplet size decreased with pressure, and the organogel-nanoemulsion could achieve good stability at low SOR.Overall, the research described in the current article show that organogel-nanoemulsion containing with D-limonene and nisin may be an effective antimicrobial system for the production and preservation of food.

View Article: PubMed Central - PubMed

Affiliation: State Key Laboratory of Chemical Resource Engineering, Beijing University of Chemical Technology Beijing, China.

ABSTRACT
The aim of this study was to investigate a novel delivery system containing D-limonene and nisin by food organogel-nanoemulsion and study its effect on the antimicrobial activity. Organogel-nanoemulsion containing with D-limonene and nisin or without nisin was prepared by a homogenization method. Factors that may affect the droplet size and stability of organogel-nanoemulsion such as pressure and surfactant to oil ratio (SOR) were studied. The average droplet size decreased with pressure, and the organogel-nanoemulsion could achieve good stability at low SOR. Positive effects and outstanding antimicrobial activities of organogel-nanoemulsion containing with D-limonene and nisin were confirmed by minimal inhibitory concentrations comparison, growth curves of bacteria, scanning electron microscopy and determination of cell constituents' release. Furthermore, the organogel-nanoemulsion applied as food preservative in milk also shown excellent antimicrobial performance. Overall, the research described in the current article show that organogel-nanoemulsion containing with D-limonene and nisin may be an effective antimicrobial system for the production and preservation of food.

No MeSH data available.


The particle size distributions of organogel-nanoemulsion prepared under different homogenizing pressures were analyzed by DLS [size distributions by volume (A) and intensity (B)].
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Figure 1: The particle size distributions of organogel-nanoemulsion prepared under different homogenizing pressures were analyzed by DLS [size distributions by volume (A) and intensity (B)].

Mentions: In order to achieve homogeneous and stable organogel-nanoemulsions, and establish the most appropriate surfactant to oil ratio (SOR) and pressure, which contribute to the formulation, size distribution and, more importantly, stability of organogel-nanoemulsions, the preparation process was optimized at first, a series of emulsion processes were prepared under different pressures and SOR values. All the nanoemulsion samples contained D-limonene and nisin of 6%, 15% (w/w). For pressure optimization, a wide range of preparation pressures (30, 50, 80, and 100 MPa) from high pressure homogenizer were utilized to explore and compare the particle size distributions. As the results shown in Figure 1, both Volume (%) value (Figure 1A) and Intensity (%) value (Figure 1B) of particle size distributions of all samples displayed bimodal results, in which the vast majority of the droplet population had a droplet-size distribution around 100 or 10 nm, only a small population around 10 μm. The highest homogenizing pressure of 100 MPa prepared the minimum droplet size of 10 nm by Volume (%) value (Figure 1A), which could provide large specific surface area and stable capacity for the following antimicrobial experiments of organogel-nanoemulsions.


Organogel-nanoemulsion containing nisin and D-limonene and its antimicrobial activity.

Bei W, Zhou Y, Xing X, Zahi MR, Li Y, Yuan Q, Liang H - Front Microbiol (2015)

The particle size distributions of organogel-nanoemulsion prepared under different homogenizing pressures were analyzed by DLS [size distributions by volume (A) and intensity (B)].
© Copyright Policy
Related In: Results  -  Collection

License
Show All Figures
getmorefigures.php?uid=PMC4585035&req=5

Figure 1: The particle size distributions of organogel-nanoemulsion prepared under different homogenizing pressures were analyzed by DLS [size distributions by volume (A) and intensity (B)].
Mentions: In order to achieve homogeneous and stable organogel-nanoemulsions, and establish the most appropriate surfactant to oil ratio (SOR) and pressure, which contribute to the formulation, size distribution and, more importantly, stability of organogel-nanoemulsions, the preparation process was optimized at first, a series of emulsion processes were prepared under different pressures and SOR values. All the nanoemulsion samples contained D-limonene and nisin of 6%, 15% (w/w). For pressure optimization, a wide range of preparation pressures (30, 50, 80, and 100 MPa) from high pressure homogenizer were utilized to explore and compare the particle size distributions. As the results shown in Figure 1, both Volume (%) value (Figure 1A) and Intensity (%) value (Figure 1B) of particle size distributions of all samples displayed bimodal results, in which the vast majority of the droplet population had a droplet-size distribution around 100 or 10 nm, only a small population around 10 μm. The highest homogenizing pressure of 100 MPa prepared the minimum droplet size of 10 nm by Volume (%) value (Figure 1A), which could provide large specific surface area and stable capacity for the following antimicrobial experiments of organogel-nanoemulsions.

Bottom Line: The aim of this study was to investigate a novel delivery system containing D-limonene and nisin by food organogel-nanoemulsion and study its effect on the antimicrobial activity.The average droplet size decreased with pressure, and the organogel-nanoemulsion could achieve good stability at low SOR.Overall, the research described in the current article show that organogel-nanoemulsion containing with D-limonene and nisin may be an effective antimicrobial system for the production and preservation of food.

View Article: PubMed Central - PubMed

Affiliation: State Key Laboratory of Chemical Resource Engineering, Beijing University of Chemical Technology Beijing, China.

ABSTRACT
The aim of this study was to investigate a novel delivery system containing D-limonene and nisin by food organogel-nanoemulsion and study its effect on the antimicrobial activity. Organogel-nanoemulsion containing with D-limonene and nisin or without nisin was prepared by a homogenization method. Factors that may affect the droplet size and stability of organogel-nanoemulsion such as pressure and surfactant to oil ratio (SOR) were studied. The average droplet size decreased with pressure, and the organogel-nanoemulsion could achieve good stability at low SOR. Positive effects and outstanding antimicrobial activities of organogel-nanoemulsion containing with D-limonene and nisin were confirmed by minimal inhibitory concentrations comparison, growth curves of bacteria, scanning electron microscopy and determination of cell constituents' release. Furthermore, the organogel-nanoemulsion applied as food preservative in milk also shown excellent antimicrobial performance. Overall, the research described in the current article show that organogel-nanoemulsion containing with D-limonene and nisin may be an effective antimicrobial system for the production and preservation of food.

No MeSH data available.