Limits...
Alcohol, Smoking, Physical Activity, Protein, and Lower Urinary Tract Symptoms: Prospective Longitudinal Cohort.

Choo MS, Han JH, Shin TY, Ko K, Lee WK, Cho ST, Lee SK, Lee SH - Int Neurourol J (2015)

Bottom Line: Of these, 547 participants were followed up for 3 years and the data was analyzed in 2014.Symptom deterioration was defined as a score of ≥8 points during the 3-year follow-up period.Physical activity had a protective effect on voiding subsymptoms.

View Article: PubMed Central - PubMed

Affiliation: Department of Urology, Hallym University Dongtan Sacred Heart Hospital, Hwaseong, Korea.

ABSTRACT

Purpose: To evaluate risk factors for deterioration of lower urinary tract symptoms (LUTS) in elderly men in a community-based, prospective longitudinal cohort study.

Methods: In a suburban area in Korea, 1,514 subjects aged ≥45 years were randomly selected by systematic sampling. A total of 918 elderly subjects were enrolled in this in-depth clinical study in 2004. Of these, 547 participants were followed up for 3 years and the data was analyzed in 2014. Standard questionnaires were administered face-to-face by trained interviewers. After excluding women, 224 male participants with complete data including transrectal ultrasonography were included in the final analysis. LUTS were diagnosed using the International Prostate Symptom Score (IPSS) questionnaire. Symptom deterioration was defined as a score of ≥8 points during the 3-year follow-up period.

Results: LUTS prevalence increased to 13.1% and the mean IPSS increased by 2.6 points during the 3-year period. After adjusting for confounders, a smoking history of ≥50 pack-years was an independent risk factor for deterioration of LUTS and storage subsymptoms compared with no history of smoking (3.1 and 5.1 odds, respectively). Physical activity had a protective effect on voiding subsymptoms. However, high protein diet and alcohol intake were not associated with LUTS deterioration.

Conclusions: The LUTS prevalence among elderly men living in a suburban area increased to 13.1% and the IPSS increased by 2.6 points during the 3-year period. A history of heavy smoking, low physical activity, and high protein intake were associated with LUTS deterioration. However, there was no significant association between alcohol intake and LUTS deterioration.

No MeSH data available.


Related in: MedlinePlus

Deterioration of lower urinary tract symptoms (LUTS) during the 3-year follow-up period. (A) Changes in the prevalence of moderate to severe LUTS in elderly men during the 3-year follow-up period; (B) changes in the International Prostate Symptom Score (IPSS) total score, voiding and storage symptoms, and the quality of life (QoL) subscore in elderly men during the 3-year follow-up period. *P≤0.05.
© Copyright Policy
Related In: Results  -  Collection

License
getmorefigures.php?uid=PMC4582093&req=5

f2-inj-19-3-197: Deterioration of lower urinary tract symptoms (LUTS) during the 3-year follow-up period. (A) Changes in the prevalence of moderate to severe LUTS in elderly men during the 3-year follow-up period; (B) changes in the International Prostate Symptom Score (IPSS) total score, voiding and storage symptoms, and the quality of life (QoL) subscore in elderly men during the 3-year follow-up period. *P≤0.05.

Mentions: Of the 224 participants, 124 (55.4%) had moderate or severe LUTS at baseline, which increased to 153 (68.3%) after the 3-year follow-up period and corresponded to an increase of 13.1% in the prevalence of LUTS during the follow-up period, and 4.43% per year (Fig. 2A). The average of the total IPSS increased by 2.56±8.86 points, from 10.73±8.89 to 13.29±9.11 (P <0.001). The average voiding and storage subscores increased by 1.27 ±6.38 points, from 6.52 ±6.21 to 7.79 ±5.78 (P <0.001), and by 1.29±3.66, from 4.21±3.91 to 5.50±3.94 (P <0.001), respectively, over 3 years (Fig. 2B).


Alcohol, Smoking, Physical Activity, Protein, and Lower Urinary Tract Symptoms: Prospective Longitudinal Cohort.

Choo MS, Han JH, Shin TY, Ko K, Lee WK, Cho ST, Lee SK, Lee SH - Int Neurourol J (2015)

Deterioration of lower urinary tract symptoms (LUTS) during the 3-year follow-up period. (A) Changes in the prevalence of moderate to severe LUTS in elderly men during the 3-year follow-up period; (B) changes in the International Prostate Symptom Score (IPSS) total score, voiding and storage symptoms, and the quality of life (QoL) subscore in elderly men during the 3-year follow-up period. *P≤0.05.
© Copyright Policy
Related In: Results  -  Collection

License
Show All Figures
getmorefigures.php?uid=PMC4582093&req=5

f2-inj-19-3-197: Deterioration of lower urinary tract symptoms (LUTS) during the 3-year follow-up period. (A) Changes in the prevalence of moderate to severe LUTS in elderly men during the 3-year follow-up period; (B) changes in the International Prostate Symptom Score (IPSS) total score, voiding and storage symptoms, and the quality of life (QoL) subscore in elderly men during the 3-year follow-up period. *P≤0.05.
Mentions: Of the 224 participants, 124 (55.4%) had moderate or severe LUTS at baseline, which increased to 153 (68.3%) after the 3-year follow-up period and corresponded to an increase of 13.1% in the prevalence of LUTS during the follow-up period, and 4.43% per year (Fig. 2A). The average of the total IPSS increased by 2.56±8.86 points, from 10.73±8.89 to 13.29±9.11 (P <0.001). The average voiding and storage subscores increased by 1.27 ±6.38 points, from 6.52 ±6.21 to 7.79 ±5.78 (P <0.001), and by 1.29±3.66, from 4.21±3.91 to 5.50±3.94 (P <0.001), respectively, over 3 years (Fig. 2B).

Bottom Line: Of these, 547 participants were followed up for 3 years and the data was analyzed in 2014.Symptom deterioration was defined as a score of ≥8 points during the 3-year follow-up period.Physical activity had a protective effect on voiding subsymptoms.

View Article: PubMed Central - PubMed

Affiliation: Department of Urology, Hallym University Dongtan Sacred Heart Hospital, Hwaseong, Korea.

ABSTRACT

Purpose: To evaluate risk factors for deterioration of lower urinary tract symptoms (LUTS) in elderly men in a community-based, prospective longitudinal cohort study.

Methods: In a suburban area in Korea, 1,514 subjects aged ≥45 years were randomly selected by systematic sampling. A total of 918 elderly subjects were enrolled in this in-depth clinical study in 2004. Of these, 547 participants were followed up for 3 years and the data was analyzed in 2014. Standard questionnaires were administered face-to-face by trained interviewers. After excluding women, 224 male participants with complete data including transrectal ultrasonography were included in the final analysis. LUTS were diagnosed using the International Prostate Symptom Score (IPSS) questionnaire. Symptom deterioration was defined as a score of ≥8 points during the 3-year follow-up period.

Results: LUTS prevalence increased to 13.1% and the mean IPSS increased by 2.6 points during the 3-year period. After adjusting for confounders, a smoking history of ≥50 pack-years was an independent risk factor for deterioration of LUTS and storage subsymptoms compared with no history of smoking (3.1 and 5.1 odds, respectively). Physical activity had a protective effect on voiding subsymptoms. However, high protein diet and alcohol intake were not associated with LUTS deterioration.

Conclusions: The LUTS prevalence among elderly men living in a suburban area increased to 13.1% and the IPSS increased by 2.6 points during the 3-year period. A history of heavy smoking, low physical activity, and high protein intake were associated with LUTS deterioration. However, there was no significant association between alcohol intake and LUTS deterioration.

No MeSH data available.


Related in: MedlinePlus