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Structural and functional hepatocyte polarity and liver disease.

Gissen P, Arias IM - J. Hepatol. (2015)

Bottom Line: Hepatocyte depolarization frequently occurs but is rarely recognized because hematoxylin-eosin staining does not identify the bile canaliculus.However, the molecular mechanisms underlying these defects are not well understood.Here we aim to provide an update on the key factors determining hepatocyte polarity and how it is affected in inherited and acquired diseases.

View Article: PubMed Central - PubMed

Affiliation: MRC Laboratory for Molecular Cell Biology, University College London, London, UK; UCL Institute of Child Health, London, UK; Great Ormond Street Hospital, London, UK. Electronic address: p.gissen@ucl.ac.uk.

No MeSH data available.


Related in: MedlinePlus

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Structural and functional hepatocyte polarity and liver disease.

Gissen P, Arias IM - J. Hepatol. (2015)

© Copyright Policy - CC BY
Related In: Results  -  Collection

License
Show All Figures
getmorefigures.php?uid=PMC4582071&req=5

Bottom Line: Hepatocyte depolarization frequently occurs but is rarely recognized because hematoxylin-eosin staining does not identify the bile canaliculus.However, the molecular mechanisms underlying these defects are not well understood.Here we aim to provide an update on the key factors determining hepatocyte polarity and how it is affected in inherited and acquired diseases.

View Article: PubMed Central - PubMed

Affiliation: MRC Laboratory for Molecular Cell Biology, University College London, London, UK; UCL Institute of Child Health, London, UK; Great Ormond Street Hospital, London, UK. Electronic address: p.gissen@ucl.ac.uk.

No MeSH data available.


Related in: MedlinePlus