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Nutritional Risk Screening 2002 as a Predictor of Outcome During General Ward-Based Noninvasive Ventilation in Chronic Obstructive Pulmonary Disease with Respiratory Failure.

Cui J, Wan Q, Wu X, Zeng Y, Jiang L, Ao D, Wang F, Chen T, Li Y - Med. Sci. Monit. (2015)

Bottom Line: Patients were divided into NRS2002 score ≥3 and NRS2002 score <3 groups and NIV failure rates were compared between both groups.RESULTS Of the 233 patients, 71 (30.5%) were not successfully treated by NIPPV.The failure rate was significantly higher in the NRS2002 score ≥3 group (35.23%) in comparison with patients with NRS2002 score <3 (15.79%) (p<0.05).

View Article: PubMed Central - PubMed

Affiliation: Department of Respiratory Medicine, West China Hospital, Sichuan University, Chengdu, Sichuan, China (mainland).

ABSTRACT
BACKGROUND Noninvasive ventilation (NIV) may reduce the need for intubation and mortality associated with chronic obstructive pulmonary disease (COPD) with type II respiratory failure. Early and simple predictors of NIV outcome could improve clinical management. This study aimed to assess whether nutritional risk screening 2002 (NRS2002) is a useful outcome predictor in COPD patients with type II respiratory failure treated by noninvasive positive pressure ventilation (NIPPV). MATERIAL AND METHODS This prospective observational study enrolled COPD patients with type II respiratory failure who accepted NIPPV. Patients were submitted to NRS2002 evaluation upon admission. Biochemical tests were performed the next day and blood gas analysis was carried out prior to NIPPV treatment and 4 hours thereafter. Patients were divided into NRS2002 score ≥3 and NRS2002 score <3 groups and NIV failure rates were compared between both groups. RESULTS Of the 233 patients, 71 (30.5%) were not successfully treated by NIPPV. The failure rate was significantly higher in the NRS2002 score ≥3 group (35.23%) in comparison with patients with NRS2002 score <3 (15.79%) (p<0.05). Multivariate analysis indicated that PaCO2 (OR 1.25, 95%CI 1.172-1.671, p<0.05) prior to NIPPV treatment and NRS2002 score ≥3 (OR 1.76, 95%CI 1.303-2.374, p<0.05) were independent predictive factors for NIPPV treatment failure. CONCLUSIONS NRS2002 score ≥3 and PaCO2 values at admission may predict unsuccessful NIPPV treatment of COPD patients with type II respiratory failure and help to adjust therapeutic strategies. NRS2002 is a noninvasive and simple method for predicting NIPPV treatment outcome.

No MeSH data available.


Related in: MedlinePlus

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f1-medscimonit-21-2786: Flow diagram for this study.

Mentions: A total of 285 COPD subjects with type II respiratory failure accepted NIV treatment, of which 237 met the enrolment criteria. One subject was excluded for uncertainty of weight changes in the preceding 3 months, and 3 subjects quit the study for inadaptability to masks. Finally, 233 cases were enrolled in the study (Figure 1), including 176 and 57 patients in the NRS2002 score ≥3 and NRS2002 score <3 groups, respectively (Table 1). The 2 groups were similar in most demographic and baseline data. However, the NRS2002 score ≥3 group was composed of older individuals (72±8 vs. 65±8 years, P<0.001) and lower male percentage (65.3 vs. 84.2%, P=0.007) in comparison with the NRS2002 score <3 group; in addition, the time from admission to NIV administration was slightly higher in the NRS2002 score ≥3 group than patients with NRS2002 score <3 (43.49±20.57 vs. 36.12±19.20 h, P=0.018) (Table 1).


Nutritional Risk Screening 2002 as a Predictor of Outcome During General Ward-Based Noninvasive Ventilation in Chronic Obstructive Pulmonary Disease with Respiratory Failure.

Cui J, Wan Q, Wu X, Zeng Y, Jiang L, Ao D, Wang F, Chen T, Li Y - Med. Sci. Monit. (2015)

Flow diagram for this study.
© Copyright Policy
Related In: Results  -  Collection

Show All Figures
getmorefigures.php?uid=PMC4581684&req=5

f1-medscimonit-21-2786: Flow diagram for this study.
Mentions: A total of 285 COPD subjects with type II respiratory failure accepted NIV treatment, of which 237 met the enrolment criteria. One subject was excluded for uncertainty of weight changes in the preceding 3 months, and 3 subjects quit the study for inadaptability to masks. Finally, 233 cases were enrolled in the study (Figure 1), including 176 and 57 patients in the NRS2002 score ≥3 and NRS2002 score <3 groups, respectively (Table 1). The 2 groups were similar in most demographic and baseline data. However, the NRS2002 score ≥3 group was composed of older individuals (72±8 vs. 65±8 years, P<0.001) and lower male percentage (65.3 vs. 84.2%, P=0.007) in comparison with the NRS2002 score <3 group; in addition, the time from admission to NIV administration was slightly higher in the NRS2002 score ≥3 group than patients with NRS2002 score <3 (43.49±20.57 vs. 36.12±19.20 h, P=0.018) (Table 1).

Bottom Line: Patients were divided into NRS2002 score ≥3 and NRS2002 score <3 groups and NIV failure rates were compared between both groups.RESULTS Of the 233 patients, 71 (30.5%) were not successfully treated by NIPPV.The failure rate was significantly higher in the NRS2002 score ≥3 group (35.23%) in comparison with patients with NRS2002 score <3 (15.79%) (p<0.05).

View Article: PubMed Central - PubMed

Affiliation: Department of Respiratory Medicine, West China Hospital, Sichuan University, Chengdu, Sichuan, China (mainland).

ABSTRACT
BACKGROUND Noninvasive ventilation (NIV) may reduce the need for intubation and mortality associated with chronic obstructive pulmonary disease (COPD) with type II respiratory failure. Early and simple predictors of NIV outcome could improve clinical management. This study aimed to assess whether nutritional risk screening 2002 (NRS2002) is a useful outcome predictor in COPD patients with type II respiratory failure treated by noninvasive positive pressure ventilation (NIPPV). MATERIAL AND METHODS This prospective observational study enrolled COPD patients with type II respiratory failure who accepted NIPPV. Patients were submitted to NRS2002 evaluation upon admission. Biochemical tests were performed the next day and blood gas analysis was carried out prior to NIPPV treatment and 4 hours thereafter. Patients were divided into NRS2002 score ≥3 and NRS2002 score <3 groups and NIV failure rates were compared between both groups. RESULTS Of the 233 patients, 71 (30.5%) were not successfully treated by NIPPV. The failure rate was significantly higher in the NRS2002 score ≥3 group (35.23%) in comparison with patients with NRS2002 score <3 (15.79%) (p<0.05). Multivariate analysis indicated that PaCO2 (OR 1.25, 95%CI 1.172-1.671, p<0.05) prior to NIPPV treatment and NRS2002 score ≥3 (OR 1.76, 95%CI 1.303-2.374, p<0.05) were independent predictive factors for NIPPV treatment failure. CONCLUSIONS NRS2002 score ≥3 and PaCO2 values at admission may predict unsuccessful NIPPV treatment of COPD patients with type II respiratory failure and help to adjust therapeutic strategies. NRS2002 is a noninvasive and simple method for predicting NIPPV treatment outcome.

No MeSH data available.


Related in: MedlinePlus