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Cervical Stand-Alone Polyetheretherketone Cage versus Zero-Profile Anchored Spacer in Single-Level Anterior Cervical Discectomy and Fusion : Minimum 2-Year Assessment of Radiographic and Clinical Outcome.

Cho HJ, Hur JW, Lee JB, Han JS, Cho TH, Park JY - J Korean Neurosurg Soc (2015)

Bottom Line: We compared the clinical and radiographic outcomes of stand-alone polyetheretherketone (PEEK) cage and Zero-Profile anchored spacer (Zero-P) for single level anterior cervical discectomy and fusion (ACDF).Demographic features and the clinical outcome showed no difference between two groups.The change between final follow-up (24 months) and immediate post-op of Cobb-segmental angle (p=0.027), disc height (p=0.002), vertebral body height (p=0.033) showed statistically better outcome for the Zero-P group than the cage group, respectively.

View Article: PubMed Central - PubMed

Affiliation: Department of Neurosurgery, Korea University Anam Hospital, College of Medicine, Korea University, Seoul, Korea.

ABSTRACT

Objective: We compared the clinical and radiographic outcomes of stand-alone polyetheretherketone (PEEK) cage and Zero-Profile anchored spacer (Zero-P) for single level anterior cervical discectomy and fusion (ACDF).

Methods: We retrospectively reviewed 121 patients who underwent single level ACDF within 2 years (Jan 2011-Jan 2013) in a single institute. Total 50 patients were included for the analysis who were evaluated more than 2-year follow-up. Twenty-nine patients were allocated to the cage group (m : f=19 : 10) and 21 for Zero-P group (m : f=12 : 9). Clinical (neck disability index, visual analogue scale arm and neck) and radiographic (Cobb angle-segmental and global cervical, disc height, vertebral height) assessments were followed at pre-operative, immediate post-operative, post-3, 6, 12, and 24 month periods.

Results: Demographic features and the clinical outcome showed no difference between two groups. The change between final follow-up (24 months) and immediate post-op of Cobb-segmental angle (p=0.027), disc height (p=0.002), vertebral body height (p=0.033) showed statistically better outcome for the Zero-P group than the cage group, respectively.

Conclusion: The Zero-Profile anchored spacer has some advantage after cage for maintaining segmental lordosis and lowering subsidence rate after single level anterior cervical discectomy and fusion.

No MeSH data available.


Related in: MedlinePlus

Serial follow up graph for Cobb-s angle (°). The Cobb-s angle shows improvement after immediate post-op and declines as time pass for both group. Change after immediate post-op and post-op 24-month shows significant difference between two groups (*p=0.027), the Zero-P group has lesser decline. Zero-P : Zero-Profile.
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Figure 2: Serial follow up graph for Cobb-s angle (°). The Cobb-s angle shows improvement after immediate post-op and declines as time pass for both group. Change after immediate post-op and post-op 24-month shows significant difference between two groups (*p=0.027), the Zero-P group has lesser decline. Zero-P : Zero-Profile.

Mentions: The Cobb-s immediately after the surgery was 3.7±2.8 for the cage group and 2.4±3.4 for the Zero-P group (p=0.221). These values worsened gradually, and the 24-month follow-up values were 0.2±2.5 and 0.3±3.2, respectively (p=0.812) (Fig. 2). The changes in Cobb-s between the immediately post-operative and pre-operative time points and between the 24-month post-operative and pre-operative time points were not significantly different between the groups (p>0.05). However, the difference between the 24-month post-operative and the immediately post-operative Cobb-s was significantly different between the two groups (p=0.027) (Table 4). Comparing the bone fusion rate, there were no statistical differences between two groups at any periods (p>0.05) (Table 5).


Cervical Stand-Alone Polyetheretherketone Cage versus Zero-Profile Anchored Spacer in Single-Level Anterior Cervical Discectomy and Fusion : Minimum 2-Year Assessment of Radiographic and Clinical Outcome.

Cho HJ, Hur JW, Lee JB, Han JS, Cho TH, Park JY - J Korean Neurosurg Soc (2015)

Serial follow up graph for Cobb-s angle (°). The Cobb-s angle shows improvement after immediate post-op and declines as time pass for both group. Change after immediate post-op and post-op 24-month shows significant difference between two groups (*p=0.027), the Zero-P group has lesser decline. Zero-P : Zero-Profile.
© Copyright Policy - open-access
Related In: Results  -  Collection

License
Show All Figures
getmorefigures.php?uid=PMC4564743&req=5

Figure 2: Serial follow up graph for Cobb-s angle (°). The Cobb-s angle shows improvement after immediate post-op and declines as time pass for both group. Change after immediate post-op and post-op 24-month shows significant difference between two groups (*p=0.027), the Zero-P group has lesser decline. Zero-P : Zero-Profile.
Mentions: The Cobb-s immediately after the surgery was 3.7±2.8 for the cage group and 2.4±3.4 for the Zero-P group (p=0.221). These values worsened gradually, and the 24-month follow-up values were 0.2±2.5 and 0.3±3.2, respectively (p=0.812) (Fig. 2). The changes in Cobb-s between the immediately post-operative and pre-operative time points and between the 24-month post-operative and pre-operative time points were not significantly different between the groups (p>0.05). However, the difference between the 24-month post-operative and the immediately post-operative Cobb-s was significantly different between the two groups (p=0.027) (Table 4). Comparing the bone fusion rate, there were no statistical differences between two groups at any periods (p>0.05) (Table 5).

Bottom Line: We compared the clinical and radiographic outcomes of stand-alone polyetheretherketone (PEEK) cage and Zero-Profile anchored spacer (Zero-P) for single level anterior cervical discectomy and fusion (ACDF).Demographic features and the clinical outcome showed no difference between two groups.The change between final follow-up (24 months) and immediate post-op of Cobb-segmental angle (p=0.027), disc height (p=0.002), vertebral body height (p=0.033) showed statistically better outcome for the Zero-P group than the cage group, respectively.

View Article: PubMed Central - PubMed

Affiliation: Department of Neurosurgery, Korea University Anam Hospital, College of Medicine, Korea University, Seoul, Korea.

ABSTRACT

Objective: We compared the clinical and radiographic outcomes of stand-alone polyetheretherketone (PEEK) cage and Zero-Profile anchored spacer (Zero-P) for single level anterior cervical discectomy and fusion (ACDF).

Methods: We retrospectively reviewed 121 patients who underwent single level ACDF within 2 years (Jan 2011-Jan 2013) in a single institute. Total 50 patients were included for the analysis who were evaluated more than 2-year follow-up. Twenty-nine patients were allocated to the cage group (m : f=19 : 10) and 21 for Zero-P group (m : f=12 : 9). Clinical (neck disability index, visual analogue scale arm and neck) and radiographic (Cobb angle-segmental and global cervical, disc height, vertebral height) assessments were followed at pre-operative, immediate post-operative, post-3, 6, 12, and 24 month periods.

Results: Demographic features and the clinical outcome showed no difference between two groups. The change between final follow-up (24 months) and immediate post-op of Cobb-segmental angle (p=0.027), disc height (p=0.002), vertebral body height (p=0.033) showed statistically better outcome for the Zero-P group than the cage group, respectively.

Conclusion: The Zero-Profile anchored spacer has some advantage after cage for maintaining segmental lordosis and lowering subsidence rate after single level anterior cervical discectomy and fusion.

No MeSH data available.


Related in: MedlinePlus