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Cervical Stand-Alone Polyetheretherketone Cage versus Zero-Profile Anchored Spacer in Single-Level Anterior Cervical Discectomy and Fusion : Minimum 2-Year Assessment of Radiographic and Clinical Outcome.

Cho HJ, Hur JW, Lee JB, Han JS, Cho TH, Park JY - J Korean Neurosurg Soc (2015)

Bottom Line: We compared the clinical and radiographic outcomes of stand-alone polyetheretherketone (PEEK) cage and Zero-Profile anchored spacer (Zero-P) for single level anterior cervical discectomy and fusion (ACDF).The change between final follow-up (24 months) and immediate post-op of Cobb-segmental angle (p=0.027), disc height (p=0.002), vertebral body height (p=0.033) showed statistically better outcome for the Zero-P group than the cage group, respectively.The Zero-Profile anchored spacer has some advantage after cage for maintaining segmental lordosis and lowering subsidence rate after single level anterior cervical discectomy and fusion.

View Article: PubMed Central - PubMed

Affiliation: Department of Neurosurgery, Korea University Anam Hospital, College of Medicine, Korea University, Seoul, Korea.

ABSTRACT

Objective: We compared the clinical and radiographic outcomes of stand-alone polyetheretherketone (PEEK) cage and Zero-Profile anchored spacer (Zero-P) for single level anterior cervical discectomy and fusion (ACDF).

Methods: We retrospectively reviewed 121 patients who underwent single level ACDF within 2 years (Jan 2011-Jan 2013) in a single institute. Total 50 patients were included for the analysis who were evaluated more than 2-year follow-up. Twenty-nine patients were allocated to the cage group (m : f=19 : 10) and 21 for Zero-P group (m : f=12 : 9). Clinical (neck disability index, visual analogue scale arm and neck) and radiographic (Cobb angle-segmental and global cervical, disc height, vertebral height) assessments were followed at pre-operative, immediate post-operative, post-3, 6, 12, and 24 month periods.

Results: Demographic features and the clinical outcome showed no difference between two groups. The change between final follow-up (24 months) and immediate post-op of Cobb-segmental angle (p=0.027), disc height (p=0.002), vertebral body height (p=0.033) showed statistically better outcome for the Zero-P group than the cage group, respectively.

Conclusion: The Zero-Profile anchored spacer has some advantage after cage for maintaining segmental lordosis and lowering subsidence rate after single level anterior cervical discectomy and fusion.

No MeSH data available.


Serial follow up graph for Cobb-s angle (°). The Cobb-s angle shows improvement after immediate post-op and declines as time pass for both group. Change after immediate post-op and post-op 24-month shows significant difference between two groups (*p=0.027), the Zero-P group has lesser decline. Zero-P : Zero-Profile.
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Figure 2: Serial follow up graph for Cobb-s angle (°). The Cobb-s angle shows improvement after immediate post-op and declines as time pass for both group. Change after immediate post-op and post-op 24-month shows significant difference between two groups (*p=0.027), the Zero-P group has lesser decline. Zero-P : Zero-Profile.

Mentions: The Cobb-s immediately after the surgery was 3.7±2.8 for the cage group and 2.4±3.4 for the Zero-P group (p=0.221). These values worsened gradually, and the 24-month follow-up values were 0.2±2.5 and 0.3±3.2, respectively (p=0.812) (Fig. 2). The changes in Cobb-s between the immediately post-operative and pre-operative time points and between the 24-month post-operative and pre-operative time points were not significantly different between the groups (p>0.05). However, the difference between the 24-month post-operative and the immediately post-operative Cobb-s was significantly different between the two groups (p=0.027) (Table 4). Comparing the bone fusion rate, there were no statistical differences between two groups at any periods (p>0.05) (Table 5).


Cervical Stand-Alone Polyetheretherketone Cage versus Zero-Profile Anchored Spacer in Single-Level Anterior Cervical Discectomy and Fusion : Minimum 2-Year Assessment of Radiographic and Clinical Outcome.

Cho HJ, Hur JW, Lee JB, Han JS, Cho TH, Park JY - J Korean Neurosurg Soc (2015)

Serial follow up graph for Cobb-s angle (°). The Cobb-s angle shows improvement after immediate post-op and declines as time pass for both group. Change after immediate post-op and post-op 24-month shows significant difference between two groups (*p=0.027), the Zero-P group has lesser decline. Zero-P : Zero-Profile.
© Copyright Policy - open-access
Related In: Results  -  Collection

License
Show All Figures
getmorefigures.php?uid=PMC4564743&req=5

Figure 2: Serial follow up graph for Cobb-s angle (°). The Cobb-s angle shows improvement after immediate post-op and declines as time pass for both group. Change after immediate post-op and post-op 24-month shows significant difference between two groups (*p=0.027), the Zero-P group has lesser decline. Zero-P : Zero-Profile.
Mentions: The Cobb-s immediately after the surgery was 3.7±2.8 for the cage group and 2.4±3.4 for the Zero-P group (p=0.221). These values worsened gradually, and the 24-month follow-up values were 0.2±2.5 and 0.3±3.2, respectively (p=0.812) (Fig. 2). The changes in Cobb-s between the immediately post-operative and pre-operative time points and between the 24-month post-operative and pre-operative time points were not significantly different between the groups (p>0.05). However, the difference between the 24-month post-operative and the immediately post-operative Cobb-s was significantly different between the two groups (p=0.027) (Table 4). Comparing the bone fusion rate, there were no statistical differences between two groups at any periods (p>0.05) (Table 5).

Bottom Line: We compared the clinical and radiographic outcomes of stand-alone polyetheretherketone (PEEK) cage and Zero-Profile anchored spacer (Zero-P) for single level anterior cervical discectomy and fusion (ACDF).The change between final follow-up (24 months) and immediate post-op of Cobb-segmental angle (p=0.027), disc height (p=0.002), vertebral body height (p=0.033) showed statistically better outcome for the Zero-P group than the cage group, respectively.The Zero-Profile anchored spacer has some advantage after cage for maintaining segmental lordosis and lowering subsidence rate after single level anterior cervical discectomy and fusion.

View Article: PubMed Central - PubMed

Affiliation: Department of Neurosurgery, Korea University Anam Hospital, College of Medicine, Korea University, Seoul, Korea.

ABSTRACT

Objective: We compared the clinical and radiographic outcomes of stand-alone polyetheretherketone (PEEK) cage and Zero-Profile anchored spacer (Zero-P) for single level anterior cervical discectomy and fusion (ACDF).

Methods: We retrospectively reviewed 121 patients who underwent single level ACDF within 2 years (Jan 2011-Jan 2013) in a single institute. Total 50 patients were included for the analysis who were evaluated more than 2-year follow-up. Twenty-nine patients were allocated to the cage group (m : f=19 : 10) and 21 for Zero-P group (m : f=12 : 9). Clinical (neck disability index, visual analogue scale arm and neck) and radiographic (Cobb angle-segmental and global cervical, disc height, vertebral height) assessments were followed at pre-operative, immediate post-operative, post-3, 6, 12, and 24 month periods.

Results: Demographic features and the clinical outcome showed no difference between two groups. The change between final follow-up (24 months) and immediate post-op of Cobb-segmental angle (p=0.027), disc height (p=0.002), vertebral body height (p=0.033) showed statistically better outcome for the Zero-P group than the cage group, respectively.

Conclusion: The Zero-Profile anchored spacer has some advantage after cage for maintaining segmental lordosis and lowering subsidence rate after single level anterior cervical discectomy and fusion.

No MeSH data available.