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Impact of physical frailty on disability in community-dwelling older adults: a prospective cohort study.

Makizako H, Shimada H, Doi T, Tsutsumimoto K, Suzuki T - BMJ Open (2015)

Bottom Line: Prospective cohort study.Participants classified as frail (HR 4.65, 95% CI 2.63 to 8.22) or prefrail (2.52, 1.56 to 4.07) at the baseline assessment had an increased risk of disability incidence compared with robust participants.Physical frailty, even being prefrail, had a strong impact on the risk of future disability.

View Article: PubMed Central - PubMed

Affiliation: Department of Preventive Gerontology, Center for Gerontology and Social Science, National Center for Geriatrics and Gerontology, Aichi, Japan.

No MeSH data available.


Related in: MedlinePlus

Flow chart of participant recruitment process (LTCI, long-term care insurance; MMSE, Mini-Mental State Examination; OSHPE, Obu Study of Health Promotion for the Elderly).
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BMJOPEN2015008462F1: Flow chart of participant recruitment process (LTCI, long-term care insurance; MMSE, Mini-Mental State Examination; OSHPE, Obu Study of Health Promotion for the Elderly).

Mentions: Of 5104 participants who completed a baseline assessment from August 2011 to February 2012, 763 had a history of Parkinson's disease (n=23), stroke (n=281), MMSE scores of <18 (n=31), missing data for frailty phenotype (n=249), were already using the LTCI system (n=124) at baseline, or had missing follow-up data (n=55), and were excluded from further analyses (figure 1). The mean (SD) age of the 4341 participants included in the study was 71.8 (5.4); 2241 (51.6%) were women. The prevalence rates of each component for determining frailty phenotype including slowness, weakness, exhaustion, low activity and weight loss were 14.8%, 16.4%, 13.2%, 28.6% and 14.8%, respectively. The prevalence of frailty and prefrailty was 6.9% and 49.6%, respectively. During the 2-year follow-up period, 168 participants (3.9%) had incident disability and were certified as needing care or support according to LTCI criteria. FigureĀ 2 shows the incident disability rates of frailty status and components.


Impact of physical frailty on disability in community-dwelling older adults: a prospective cohort study.

Makizako H, Shimada H, Doi T, Tsutsumimoto K, Suzuki T - BMJ Open (2015)

Flow chart of participant recruitment process (LTCI, long-term care insurance; MMSE, Mini-Mental State Examination; OSHPE, Obu Study of Health Promotion for the Elderly).
© Copyright Policy - open-access
Related In: Results  -  Collection

License
Show All Figures
getmorefigures.php?uid=PMC4563225&req=5

BMJOPEN2015008462F1: Flow chart of participant recruitment process (LTCI, long-term care insurance; MMSE, Mini-Mental State Examination; OSHPE, Obu Study of Health Promotion for the Elderly).
Mentions: Of 5104 participants who completed a baseline assessment from August 2011 to February 2012, 763 had a history of Parkinson's disease (n=23), stroke (n=281), MMSE scores of <18 (n=31), missing data for frailty phenotype (n=249), were already using the LTCI system (n=124) at baseline, or had missing follow-up data (n=55), and were excluded from further analyses (figure 1). The mean (SD) age of the 4341 participants included in the study was 71.8 (5.4); 2241 (51.6%) were women. The prevalence rates of each component for determining frailty phenotype including slowness, weakness, exhaustion, low activity and weight loss were 14.8%, 16.4%, 13.2%, 28.6% and 14.8%, respectively. The prevalence of frailty and prefrailty was 6.9% and 49.6%, respectively. During the 2-year follow-up period, 168 participants (3.9%) had incident disability and were certified as needing care or support according to LTCI criteria. FigureĀ 2 shows the incident disability rates of frailty status and components.

Bottom Line: Prospective cohort study.Participants classified as frail (HR 4.65, 95% CI 2.63 to 8.22) or prefrail (2.52, 1.56 to 4.07) at the baseline assessment had an increased risk of disability incidence compared with robust participants.Physical frailty, even being prefrail, had a strong impact on the risk of future disability.

View Article: PubMed Central - PubMed

Affiliation: Department of Preventive Gerontology, Center for Gerontology and Social Science, National Center for Geriatrics and Gerontology, Aichi, Japan.

No MeSH data available.


Related in: MedlinePlus