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A retrospective pilot study of correlation of cerebral augmentation effects of external counterpulsation with functional outcome after acute ischaemic stroke.

Xiong L, Lin W, Han J, Chen X, Leung TW, Soo YO, Wong LK - BMJ Open (2015)

Bottom Line: Flow velocity changes before, during and after ECP were, respectively, recorded for 3 min.TCD data were analysed based on the side ipsilateral or contralateral to the infarct.Multivariate logistic regression showed that ipsilateral CAI was independently correlated with an unfavourable functional outcome after adjusting for confounding factors.

View Article: PubMed Central - PubMed

Affiliation: Department of Medicine and Therapeutics, The Chinese University of Hong Kong, Hong Kong, Hong Kong.

No MeSH data available.


Related in: MedlinePlus

Distribution of median cerebral augmentation index on the ipsilateral side according to the 6-month modified Rankin Scale (mRS) scores. The median and its box plot are shown. Thirty-five patients had mRS=0, 5 patients mRS=1, 13 patients mRS=2, 12 patients mRS=3 and 4 patients mRS=4, whereas only 1 patient had mRS=5 and 2 patients mRS=6.
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BMJOPEN2015009233F1: Distribution of median cerebral augmentation index on the ipsilateral side according to the 6-month modified Rankin Scale (mRS) scores. The median and its box plot are shown. Thirty-five patients had mRS=0, 5 patients mRS=1, 13 patients mRS=2, 12 patients mRS=3 and 4 patients mRS=4, whereas only 1 patient had mRS=5 and 2 patients mRS=6.

Mentions: Crude ORs of CAI on the ipsilateral side (versus CAI on the contralateral side) and 6-month unfavourable functional outcome after acute ischaemic stroke were 1.118 (95% CI 1.018 to 1.229; p=0.019) and 1.011 (95% CI 0.989 to 1.034; p=0.323), respectively. After adjusting for confounding factors such as NIHSS at recruitment and ECP duration, respectively, which were the two variables most significantly different between the two groups in univariate analysis, the CAI on the ipsilateral side still showed significant association with unfavourable outcome, with ORs of 1.154 (95% CI 1.038 to 1.282; p=0.008) and 1.145 (95% CI 1.031 to 1.271; p=0.011), respectively (table 4). For 72 patients with ischaemic stroke, the distribution of median CAI on the ipsilateral side according to the 6-month mRS scores was shown in figure 1.


A retrospective pilot study of correlation of cerebral augmentation effects of external counterpulsation with functional outcome after acute ischaemic stroke.

Xiong L, Lin W, Han J, Chen X, Leung TW, Soo YO, Wong LK - BMJ Open (2015)

Distribution of median cerebral augmentation index on the ipsilateral side according to the 6-month modified Rankin Scale (mRS) scores. The median and its box plot are shown. Thirty-five patients had mRS=0, 5 patients mRS=1, 13 patients mRS=2, 12 patients mRS=3 and 4 patients mRS=4, whereas only 1 patient had mRS=5 and 2 patients mRS=6.
© Copyright Policy - open-access
Related In: Results  -  Collection

License
Show All Figures
getmorefigures.php?uid=PMC4563223&req=5

BMJOPEN2015009233F1: Distribution of median cerebral augmentation index on the ipsilateral side according to the 6-month modified Rankin Scale (mRS) scores. The median and its box plot are shown. Thirty-five patients had mRS=0, 5 patients mRS=1, 13 patients mRS=2, 12 patients mRS=3 and 4 patients mRS=4, whereas only 1 patient had mRS=5 and 2 patients mRS=6.
Mentions: Crude ORs of CAI on the ipsilateral side (versus CAI on the contralateral side) and 6-month unfavourable functional outcome after acute ischaemic stroke were 1.118 (95% CI 1.018 to 1.229; p=0.019) and 1.011 (95% CI 0.989 to 1.034; p=0.323), respectively. After adjusting for confounding factors such as NIHSS at recruitment and ECP duration, respectively, which were the two variables most significantly different between the two groups in univariate analysis, the CAI on the ipsilateral side still showed significant association with unfavourable outcome, with ORs of 1.154 (95% CI 1.038 to 1.282; p=0.008) and 1.145 (95% CI 1.031 to 1.271; p=0.011), respectively (table 4). For 72 patients with ischaemic stroke, the distribution of median CAI on the ipsilateral side according to the 6-month mRS scores was shown in figure 1.

Bottom Line: Flow velocity changes before, during and after ECP were, respectively, recorded for 3 min.TCD data were analysed based on the side ipsilateral or contralateral to the infarct.Multivariate logistic regression showed that ipsilateral CAI was independently correlated with an unfavourable functional outcome after adjusting for confounding factors.

View Article: PubMed Central - PubMed

Affiliation: Department of Medicine and Therapeutics, The Chinese University of Hong Kong, Hong Kong, Hong Kong.

No MeSH data available.


Related in: MedlinePlus