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The Deyo-Charlson and Elixhauser-van Walraven Comorbidity Indices as predictors of mortality in critically ill patients.

Ladha KS, Zhao K, Quraishi SA, Kurth T, Eikermann M, Kaafarani HM, Klein EN, Seethala R, Lee J - BMJ Open (2015)

Bottom Line: The DCCI and EVCI performed similarly across ICUs at all time points, with the exception of the neurosciences ICU, where the DCCI was superior to EVCI at all time points (1-year mortality: AUC 0.73 (95% CI 0.72 to 0.74) vs 0.68 (95% CI 0.67 to 0.70), p=0.005).The addition of basic demographic information did not change the results at any of the assessed time points.Addition of demographic data to both indices did not affect the predictive utility of these indices.

View Article: PubMed Central - PubMed

Affiliation: Division of Critical Care Medicine, Department of Anesthesia, Critical Care, and Pain Medicine, Massachusetts General Hospital, Boston, Massachusetts, USA Department of Anaesthesia, Harvard Medical School, Boston, Massachusetts, USA.

No MeSH data available.


Related in: MedlinePlus

Calibration plots for Elixhauser-van Walraven Comorbidity Index and Deyo-Charlson Comorbidity Index for prediction of 1-year mortality after admission to the intensive care unit.
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BMJOPEN2015008990F1: Calibration plots for Elixhauser-van Walraven Comorbidity Index and Deyo-Charlson Comorbidity Index for prediction of 1-year mortality after admission to the intensive care unit.

Mentions: As further sensitivity analysis, model calibration of the indices was assessed through the plotting of calibration plots with the outcome of 1-year mortality. The plots are displayed in figure 1 and demonstrate adequate calibration. When analysing the data as a survival data set, the results of the calculated AUCs from the time-dependent ROC curves were similar to the primary analysis. The AUCs across time points are displayed in figure 2. When examining the ability of both indices to predict prolonged length of stay, the EVCI outperformed for the DCCI. For prolonged ICU stay, EVCI had an AUC of 0.64 (95% CI 0.63 to 0.64) versus the DCCI that had an AUC of 0.53 (95% CI 0.53 to 0.54) with a p value for difference of <0.001. When examining the ability to predict a hospital stay of greater than 16 days, EVCI had an AUC of 0.67 (95% CI 0.67 to 0.68) versus the DCCI which had an AUC of 0.57 (95% CI 0.56 to 0.57) with a p value for difference of <0.001.


The Deyo-Charlson and Elixhauser-van Walraven Comorbidity Indices as predictors of mortality in critically ill patients.

Ladha KS, Zhao K, Quraishi SA, Kurth T, Eikermann M, Kaafarani HM, Klein EN, Seethala R, Lee J - BMJ Open (2015)

Calibration plots for Elixhauser-van Walraven Comorbidity Index and Deyo-Charlson Comorbidity Index for prediction of 1-year mortality after admission to the intensive care unit.
© Copyright Policy - open-access
Related In: Results  -  Collection

License
Show All Figures
getmorefigures.php?uid=PMC4563218&req=5

BMJOPEN2015008990F1: Calibration plots for Elixhauser-van Walraven Comorbidity Index and Deyo-Charlson Comorbidity Index for prediction of 1-year mortality after admission to the intensive care unit.
Mentions: As further sensitivity analysis, model calibration of the indices was assessed through the plotting of calibration plots with the outcome of 1-year mortality. The plots are displayed in figure 1 and demonstrate adequate calibration. When analysing the data as a survival data set, the results of the calculated AUCs from the time-dependent ROC curves were similar to the primary analysis. The AUCs across time points are displayed in figure 2. When examining the ability of both indices to predict prolonged length of stay, the EVCI outperformed for the DCCI. For prolonged ICU stay, EVCI had an AUC of 0.64 (95% CI 0.63 to 0.64) versus the DCCI that had an AUC of 0.53 (95% CI 0.53 to 0.54) with a p value for difference of <0.001. When examining the ability to predict a hospital stay of greater than 16 days, EVCI had an AUC of 0.67 (95% CI 0.67 to 0.68) versus the DCCI which had an AUC of 0.57 (95% CI 0.56 to 0.57) with a p value for difference of <0.001.

Bottom Line: The DCCI and EVCI performed similarly across ICUs at all time points, with the exception of the neurosciences ICU, where the DCCI was superior to EVCI at all time points (1-year mortality: AUC 0.73 (95% CI 0.72 to 0.74) vs 0.68 (95% CI 0.67 to 0.70), p=0.005).The addition of basic demographic information did not change the results at any of the assessed time points.Addition of demographic data to both indices did not affect the predictive utility of these indices.

View Article: PubMed Central - PubMed

Affiliation: Division of Critical Care Medicine, Department of Anesthesia, Critical Care, and Pain Medicine, Massachusetts General Hospital, Boston, Massachusetts, USA Department of Anaesthesia, Harvard Medical School, Boston, Massachusetts, USA.

No MeSH data available.


Related in: MedlinePlus