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Normative Data of Thyroid Volume-Ultrasonographic Evaluation of 422 Subjects Aged 0-55 Years.

Aydıner Ö, Karakoç Aydıner E, Akpınar İ, Turan S, Bereket A - J Clin Res Pediatr Endocrinol (2015)

Bottom Line: Final analysis covered 422 subjects (216 males, 206 females).Thyroid volume was found to significantly correlate with height, weight, age and body surface area (r=0.661, r=0.712, r=0.772 and r=0.779, respectively; p<0.0001 for all).These correlations were even stronger in subjects younger than 18 years (r=0.758, r=0.800, r=0.815 and r=0.802, respectively; p<0.0001 for all).

View Article: PubMed Central - PubMed

Affiliation: Marmara University Faculty of Medicine, Department of Pediatrics, Division of Pediatric Allergy and Immunology, İstanbul, Turkey Phone: +90 216 625 28 40 E-mail: elif_karakoc@hotmail.com.

ABSTRACT

Objective: To establish local normative data of thyroid volume assessed by ultrasonography in subjects aged 0-55 years living in İstanbul, Turkey.

Methods: Subjects without any known history of thyroid disease, of major surgery and/or chronic disease were enrolled in the study and evaluated by physical examination and thyroid ultrasonography. Thyroid gland and isthmus at usual location, each lateral lobe volume with three dimensions, ectopic thyroid tissue and echogenicity of the gland were assessed.

Results: Initially, 494 subjects were enrolled in the study. Subjects showing heterogeneous thyroid parenchyma (n=21) and/or nodule (n=51) in ultrasonography were excluded. Final analysis covered 422 subjects (216 males, 206 females). Thyroid volume was found to significantly correlate with height, weight, age and body surface area (r=0.661, r=0.712, r=0.772 and r=0.779, respectively; p<0.0001 for all). These correlations were even stronger in subjects younger than 18 years (r=0.758, r=0.800, r=0.815 and r=0.802, respectively; p<0.0001 for all).

Conclusion: The study provides updated reference norms for thyroid volume in Turkish subjects which can be used in the diagnosis and follow-up of patients with thyroid diseases.

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Related in: MedlinePlus

The correlations of thyroid volume-height in Figure 2A, thyroid volume-body weight in Figure 2B, thyroid volume-body surface area in Figure 2C and thyroid volume-age in Figure 2D are shown for subjects less than 18 years of age. Pearson’s correlation is expressed as ‘r’ coefficient at the top of the figure.
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f2: The correlations of thyroid volume-height in Figure 2A, thyroid volume-body weight in Figure 2B, thyroid volume-body surface area in Figure 2C and thyroid volume-age in Figure 2D are shown for subjects less than 18 years of age. Pearson’s correlation is expressed as ‘r’ coefficient at the top of the figure.

Mentions: When subjects younger than 18 years of age were evaluated separately, thyroid volume was also found to positively correlate with height, weight, body surface area and age (r=0.758, r=0.800, r=0.802, r=0.815, respectively; p<0.0001 for all). These data are presented in Figure 2 A-D. On the other hand, in subjects older than 18 years of age, the correlations were as follows; between thyroid volume and body weight – r=0.260, between thyroid volume and statural height – r=0.269, between thyroid volume and body surface area – r=0.299 and between thyroid volume and chronological age – r=0.306 (p<0.0001 for all).


Normative Data of Thyroid Volume-Ultrasonographic Evaluation of 422 Subjects Aged 0-55 Years.

Aydıner Ö, Karakoç Aydıner E, Akpınar İ, Turan S, Bereket A - J Clin Res Pediatr Endocrinol (2015)

The correlations of thyroid volume-height in Figure 2A, thyroid volume-body weight in Figure 2B, thyroid volume-body surface area in Figure 2C and thyroid volume-age in Figure 2D are shown for subjects less than 18 years of age. Pearson’s correlation is expressed as ‘r’ coefficient at the top of the figure.
© Copyright Policy - open-access
Related In: Results  -  Collection

License
Show All Figures
getmorefigures.php?uid=PMC4563193&req=5

f2: The correlations of thyroid volume-height in Figure 2A, thyroid volume-body weight in Figure 2B, thyroid volume-body surface area in Figure 2C and thyroid volume-age in Figure 2D are shown for subjects less than 18 years of age. Pearson’s correlation is expressed as ‘r’ coefficient at the top of the figure.
Mentions: When subjects younger than 18 years of age were evaluated separately, thyroid volume was also found to positively correlate with height, weight, body surface area and age (r=0.758, r=0.800, r=0.802, r=0.815, respectively; p<0.0001 for all). These data are presented in Figure 2 A-D. On the other hand, in subjects older than 18 years of age, the correlations were as follows; between thyroid volume and body weight – r=0.260, between thyroid volume and statural height – r=0.269, between thyroid volume and body surface area – r=0.299 and between thyroid volume and chronological age – r=0.306 (p<0.0001 for all).

Bottom Line: Final analysis covered 422 subjects (216 males, 206 females).Thyroid volume was found to significantly correlate with height, weight, age and body surface area (r=0.661, r=0.712, r=0.772 and r=0.779, respectively; p<0.0001 for all).These correlations were even stronger in subjects younger than 18 years (r=0.758, r=0.800, r=0.815 and r=0.802, respectively; p<0.0001 for all).

View Article: PubMed Central - PubMed

Affiliation: Marmara University Faculty of Medicine, Department of Pediatrics, Division of Pediatric Allergy and Immunology, İstanbul, Turkey Phone: +90 216 625 28 40 E-mail: elif_karakoc@hotmail.com.

ABSTRACT

Objective: To establish local normative data of thyroid volume assessed by ultrasonography in subjects aged 0-55 years living in İstanbul, Turkey.

Methods: Subjects without any known history of thyroid disease, of major surgery and/or chronic disease were enrolled in the study and evaluated by physical examination and thyroid ultrasonography. Thyroid gland and isthmus at usual location, each lateral lobe volume with three dimensions, ectopic thyroid tissue and echogenicity of the gland were assessed.

Results: Initially, 494 subjects were enrolled in the study. Subjects showing heterogeneous thyroid parenchyma (n=21) and/or nodule (n=51) in ultrasonography were excluded. Final analysis covered 422 subjects (216 males, 206 females). Thyroid volume was found to significantly correlate with height, weight, age and body surface area (r=0.661, r=0.712, r=0.772 and r=0.779, respectively; p<0.0001 for all). These correlations were even stronger in subjects younger than 18 years (r=0.758, r=0.800, r=0.815 and r=0.802, respectively; p<0.0001 for all).

Conclusion: The study provides updated reference norms for thyroid volume in Turkish subjects which can be used in the diagnosis and follow-up of patients with thyroid diseases.

Show MeSH
Related in: MedlinePlus