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Atypical femoral fracture due to chronic use of bisphosphonates: case report.

Temponi EF, de Carvalho Junior LH, Costa LP - Rev Bras Ortop (2015)

Bottom Line: The causal relationship between chronic use of bisphosphonates and occurrences of atypical femoral fractures has not yet been established.Atypical fractures are still rare events and the benefit from using bisphosphonates remains greater for prevention and treatment of osteoporosis.Abstract available from the publisher.

View Article: PubMed Central - PubMed

Affiliation: Hospital Madre Teresa, Belo Horizonte, MG, Brazil.

ABSTRACT
The causal relationship between chronic use of bisphosphonates and occurrences of atypical femoral fractures has not yet been established. Nonetheless, it is known that their chronic use is more related to fractures with a pattern differing from that of classical osteoporotic fractures. Atypical fractures are still rare events and the benefit from using bisphosphonates remains greater for prevention and treatment of osteoporosis. There are few studies guiding the diagnosis and management of these fractures, thus making it difficult to achieve better results. In this report, we present the case of an elderly patient with an atypical femoral fracture that was managed in accordance with guidance from the American Society for Bone and Mineral Research.

No MeSH data available.


Related in: MedlinePlus

Late-stage postoperative radiological evaluation (3 months) showing consolidation in anteroposterior (AP) view (a) and oblique view (b, c).
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fig0010: Late-stage postoperative radiological evaluation (3 months) showing consolidation in anteroposterior (AP) view (a) and oblique view (b, c).

Mentions: Today, the patient presents 4 months of postoperative evolution, with involution of the symptomatic condition and improvement of the gait pattern, and without any complaints. She already presents radiological indications of fracture consolidation (Fig. 2). Because of the history of a previous proximal femoral fracture and the atypical fracture induced by bisphosphonates (high risk of new fractures), it was decided to maintain the supplementation of calcium and vitamin D, withdraw the use of bisphosphonates and start the patient on denosumab.


Atypical femoral fracture due to chronic use of bisphosphonates: case report.

Temponi EF, de Carvalho Junior LH, Costa LP - Rev Bras Ortop (2015)

Late-stage postoperative radiological evaluation (3 months) showing consolidation in anteroposterior (AP) view (a) and oblique view (b, c).
© Copyright Policy - CC BY-NC-ND
Related In: Results  -  Collection

License
Show All Figures
getmorefigures.php?uid=PMC4563046&req=5

fig0010: Late-stage postoperative radiological evaluation (3 months) showing consolidation in anteroposterior (AP) view (a) and oblique view (b, c).
Mentions: Today, the patient presents 4 months of postoperative evolution, with involution of the symptomatic condition and improvement of the gait pattern, and without any complaints. She already presents radiological indications of fracture consolidation (Fig. 2). Because of the history of a previous proximal femoral fracture and the atypical fracture induced by bisphosphonates (high risk of new fractures), it was decided to maintain the supplementation of calcium and vitamin D, withdraw the use of bisphosphonates and start the patient on denosumab.

Bottom Line: The causal relationship between chronic use of bisphosphonates and occurrences of atypical femoral fractures has not yet been established.Atypical fractures are still rare events and the benefit from using bisphosphonates remains greater for prevention and treatment of osteoporosis.Abstract available from the publisher.

View Article: PubMed Central - PubMed

Affiliation: Hospital Madre Teresa, Belo Horizonte, MG, Brazil.

ABSTRACT
The causal relationship between chronic use of bisphosphonates and occurrences of atypical femoral fractures has not yet been established. Nonetheless, it is known that their chronic use is more related to fractures with a pattern differing from that of classical osteoporotic fractures. Atypical fractures are still rare events and the benefit from using bisphosphonates remains greater for prevention and treatment of osteoporosis. There are few studies guiding the diagnosis and management of these fractures, thus making it difficult to achieve better results. In this report, we present the case of an elderly patient with an atypical femoral fracture that was managed in accordance with guidance from the American Society for Bone and Mineral Research.

No MeSH data available.


Related in: MedlinePlus