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Quantification of Regional Breast Density in Four Quadrants Using 3D MRI-A Pilot Study.

Fwu PT, Chen JH, Li Y, Chan S, Su MY - Transl Oncol (2015)

Bottom Line: The symmetry of the quadrant BV in the left and right breasts separated by using the nipple alone, or the nipple-centroid line, was compared.Among the four quadrants, PD was the highest in the lower outer and the lowest in the upper outer (significant than the other three) quadrants (P < .05).The reorientation based on the nipple-centroid line improved the left to right quadrant symmetry, and this may provide a better standardized method to measure quantitative quadrant density.

View Article: PubMed Central - PubMed

Affiliation: Center for Functional Onco-Imaging, Department of Radiological Sciences, University of California, Irvine, CA, USA.

No MeSH data available.


Related in: MedlinePlus

The Bland–Altman plots comparing the symmetry of BV measured from the corresponding quadrant of the left and right breasts of 58 healthy women, before and after positional correction. The blue dots are before correction, and the pink triangles are after correction based on the nipple-centroid line. The x-axis denotes the mean BV of the left and right breasts, calculated as (left BV + right BV)/2. The y-axis denotes the percentage difference calculated as (left BV − right BV)/mean BV × 100%. The correction improves the agreement showing a smaller SD.
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f0020: The Bland–Altman plots comparing the symmetry of BV measured from the corresponding quadrant of the left and right breasts of 58 healthy women, before and after positional correction. The blue dots are before correction, and the pink triangles are after correction based on the nipple-centroid line. The x-axis denotes the mean BV of the left and right breasts, calculated as (left BV + right BV)/2. The y-axis denotes the percentage difference calculated as (left BV − right BV)/mean BV × 100%. The correction improves the agreement showing a smaller SD.

Mentions: Figure 3 shows the correlation of separated BV in each quadrant of the left and the right breasts before and after correction. The data points are falling closer to the unity line after correction, demonstrating that the symmetry is improved. Table 1 summarizes the left to right concordance correlation coefficients of BV in the four quadrants before and after the correction. Figure 4 shows the Bland–Altman plots comparing the symmetry of BV in each quadrant before and after correction. The range and the variance of the percentage difference became smaller after correction. The 95% limits of agreement of BV in each quadrant measured between the left and right breasts before and after correction are also shown in Table 1. The correlation and agreement for the measured BV in each of the four quadrants are all improved after the standardization by using the nipple-centroid line.


Quantification of Regional Breast Density in Four Quadrants Using 3D MRI-A Pilot Study.

Fwu PT, Chen JH, Li Y, Chan S, Su MY - Transl Oncol (2015)

The Bland–Altman plots comparing the symmetry of BV measured from the corresponding quadrant of the left and right breasts of 58 healthy women, before and after positional correction. The blue dots are before correction, and the pink triangles are after correction based on the nipple-centroid line. The x-axis denotes the mean BV of the left and right breasts, calculated as (left BV + right BV)/2. The y-axis denotes the percentage difference calculated as (left BV − right BV)/mean BV × 100%. The correction improves the agreement showing a smaller SD.
© Copyright Policy - CC BY-NC-ND
Related In: Results  -  Collection

License
Show All Figures
getmorefigures.php?uid=PMC4562976&req=5

f0020: The Bland–Altman plots comparing the symmetry of BV measured from the corresponding quadrant of the left and right breasts of 58 healthy women, before and after positional correction. The blue dots are before correction, and the pink triangles are after correction based on the nipple-centroid line. The x-axis denotes the mean BV of the left and right breasts, calculated as (left BV + right BV)/2. The y-axis denotes the percentage difference calculated as (left BV − right BV)/mean BV × 100%. The correction improves the agreement showing a smaller SD.
Mentions: Figure 3 shows the correlation of separated BV in each quadrant of the left and the right breasts before and after correction. The data points are falling closer to the unity line after correction, demonstrating that the symmetry is improved. Table 1 summarizes the left to right concordance correlation coefficients of BV in the four quadrants before and after the correction. Figure 4 shows the Bland–Altman plots comparing the symmetry of BV in each quadrant before and after correction. The range and the variance of the percentage difference became smaller after correction. The 95% limits of agreement of BV in each quadrant measured between the left and right breasts before and after correction are also shown in Table 1. The correlation and agreement for the measured BV in each of the four quadrants are all improved after the standardization by using the nipple-centroid line.

Bottom Line: The symmetry of the quadrant BV in the left and right breasts separated by using the nipple alone, or the nipple-centroid line, was compared.Among the four quadrants, PD was the highest in the lower outer and the lowest in the upper outer (significant than the other three) quadrants (P < .05).The reorientation based on the nipple-centroid line improved the left to right quadrant symmetry, and this may provide a better standardized method to measure quantitative quadrant density.

View Article: PubMed Central - PubMed

Affiliation: Center for Functional Onco-Imaging, Department of Radiological Sciences, University of California, Irvine, CA, USA.

No MeSH data available.


Related in: MedlinePlus