Limits...
Inorganic nanolayers: structure, preparation, and biomedical applications.

Saifullah B, Hussein MZ - Int J Nanomedicine (2015)

Bottom Line: Inorganic nanolayers have been the focus for researchers over the last decade, resulting in widening application horizons, especially in the field of biomedical science.These nanolayers have been widely applied in drug and gene delivery.The suitability of inorganic nanolayers for application in drug delivery, gene delivery, biosensing technology, and bioimaging science makes them ideal materials to be applied for theranostic purposes.

View Article: PubMed Central - PubMed

Affiliation: Materials Synthesis and Characterization Laboratory, Institute of Advanced Technology (ITMA), Universiti Putra Malaysia, Serdang, Malaysia.

ABSTRACT
Hydrotalcite-like compounds are two-dimensional inorganic nanolayers also known as clay minerals or anionic clays or layered double hydroxides/layered hydroxy salts, and have emerged as a single type of material with numerous biomedical applications, such as drug delivery, gene delivery, cosmetics, and biosensing. Inorganic nanolayers are promising materials due to their fascinating properties, such as ease of preparation, ability to intercalate different type of anions (inorganic, organic, biomolecules, and even genes), high thermal stability, delivery of intercalated anions in a sustained manner, high biocompatibility, and easy biodegradation. Inorganic nanolayers have been the focus for researchers over the last decade, resulting in widening application horizons, especially in the field of biomedical science. These nanolayers have been widely applied in drug and gene delivery. They have also been applied in biosensing technology, and most recently in bioimaging science. The suitability of inorganic nanolayers for application in drug delivery, gene delivery, biosensing technology, and bioimaging science makes them ideal materials to be applied for theranostic purposes. In this paper, we review the structure, methods of preparation, and latest advances made by inorganic nanolayers in such biomedical applications as drug delivery, gene delivery, biosensing, and bioimaging.

No MeSH data available.


Applications of inorganic nanolayers.
© Copyright Policy
Related In: Results  -  Collection

License
getmorefigures.php?uid=PMC4562743&req=5

f1-ijn-10-5609: Applications of inorganic nanolayers.

Mentions: Drug delivery, gene delivery, biosensing science, and bioimaging technology are the key tools of modern-day biomedical sciences. Different materials are used for the application of the aforementioned biomedical tools but there are certain issues related to different materials, such as cytotoxicity, lack of biodegradation, and different types of material being used for individual application.9 Inorganic nanolayers have many advantages for biomedical applications, such as having been proven to possess very high in vitro and in vivo biocompatibility and biodegradability, and a single material can be applied for drug delivery, gene delivery, biosensing, and in bioimaging sciences. Figure 1 shows the different applications of inorganic nanolayers. This review addresses several aspects, such as structure, preparations, various biomedical sustained-release properties, in vitro and in vivo biocompatibilities, and theranostic applications. There have been many reviews regarding inorganic nanolayers, but most of them have focused on one dimension, ie, their drug-delivery applications.


Inorganic nanolayers: structure, preparation, and biomedical applications.

Saifullah B, Hussein MZ - Int J Nanomedicine (2015)

Applications of inorganic nanolayers.
© Copyright Policy
Related In: Results  -  Collection

License
Show All Figures
getmorefigures.php?uid=PMC4562743&req=5

f1-ijn-10-5609: Applications of inorganic nanolayers.
Mentions: Drug delivery, gene delivery, biosensing science, and bioimaging technology are the key tools of modern-day biomedical sciences. Different materials are used for the application of the aforementioned biomedical tools but there are certain issues related to different materials, such as cytotoxicity, lack of biodegradation, and different types of material being used for individual application.9 Inorganic nanolayers have many advantages for biomedical applications, such as having been proven to possess very high in vitro and in vivo biocompatibility and biodegradability, and a single material can be applied for drug delivery, gene delivery, biosensing, and in bioimaging sciences. Figure 1 shows the different applications of inorganic nanolayers. This review addresses several aspects, such as structure, preparations, various biomedical sustained-release properties, in vitro and in vivo biocompatibilities, and theranostic applications. There have been many reviews regarding inorganic nanolayers, but most of them have focused on one dimension, ie, their drug-delivery applications.

Bottom Line: Inorganic nanolayers have been the focus for researchers over the last decade, resulting in widening application horizons, especially in the field of biomedical science.These nanolayers have been widely applied in drug and gene delivery.The suitability of inorganic nanolayers for application in drug delivery, gene delivery, biosensing technology, and bioimaging science makes them ideal materials to be applied for theranostic purposes.

View Article: PubMed Central - PubMed

Affiliation: Materials Synthesis and Characterization Laboratory, Institute of Advanced Technology (ITMA), Universiti Putra Malaysia, Serdang, Malaysia.

ABSTRACT
Hydrotalcite-like compounds are two-dimensional inorganic nanolayers also known as clay minerals or anionic clays or layered double hydroxides/layered hydroxy salts, and have emerged as a single type of material with numerous biomedical applications, such as drug delivery, gene delivery, cosmetics, and biosensing. Inorganic nanolayers are promising materials due to their fascinating properties, such as ease of preparation, ability to intercalate different type of anions (inorganic, organic, biomolecules, and even genes), high thermal stability, delivery of intercalated anions in a sustained manner, high biocompatibility, and easy biodegradation. Inorganic nanolayers have been the focus for researchers over the last decade, resulting in widening application horizons, especially in the field of biomedical science. These nanolayers have been widely applied in drug and gene delivery. They have also been applied in biosensing technology, and most recently in bioimaging science. The suitability of inorganic nanolayers for application in drug delivery, gene delivery, biosensing technology, and bioimaging science makes them ideal materials to be applied for theranostic purposes. In this paper, we review the structure, methods of preparation, and latest advances made by inorganic nanolayers in such biomedical applications as drug delivery, gene delivery, biosensing, and bioimaging.

No MeSH data available.