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Evaluation of the Effectiveness of a Psychoeducational Intervention in Treatment-Naïve Patients with Antidepressant Medication in Primary Care: A Randomized Controlled Trial.

Casañas R, Catalán R, Penadés R, Real J, Valero S, Muñoz M, Lalucat-Jo L, Casas M - ScientificWorldJournal (2015)

Bottom Line: The analysis only showed significant differences in the BDI score posttreatment (P = 0.008; effect size Cohen's d' = 0.55).The PE intervention is an effective treatment in the depressive population not treated with AD medication.Before taking an AD, psychoeducational intervention should be considered.

View Article: PubMed Central - PubMed

Affiliation: Research Department, Centre Higiene Mental (CHM) Les Corts, C/Numancia, 103-105 Bajos, 08029 Barcelona, Spain ; Psychiatry and Legal Medicine Department, Universidad Autónoma de Barcelona, Barcelona, Spain ; Primary Healthcare University Research Institute IDIAP-Jordi Gol, Institut Català de la Salut (ICS), C/Sardenya 375, 08036 Barcelona, Spain.

ABSTRACT

Background: There is evidence supporting the effectiveness of psychoeducation (PE) in patients with symptoms of depression in primary care (PC), but very few studies have assessed this intervention in antidepressant-naïve patients. The aim of this study is to assess the effectiveness of a PE program in these patients, since the use of antidepressant (AD) medication may interfere with the effects of the intervention.

Methods: 106 participants were included, 50 from the PE program (12 weekly 1.5-hour sessions) and 56 from the control group (CG) that received the usual care. Patients were assessed at baseline and at 3, 6, and 9 months. The main outcome measures were the Beck Depression Inventory (BDI) and remission based on the BDI. The analysis was carried out on an intention-to-treat basis.

Results: The PE program group showed remission of symptoms of 40% (P = 0.001) posttreatment and 42% (P = 0.012) at 6 months. The analysis only showed significant differences in the BDI score posttreatment (P = 0.008; effect size Cohen's d' = 0.55).

Conclusions: The PE intervention is an effective treatment in the depressive population not treated with AD medication. Before taking an AD, psychoeducational intervention should be considered.

No MeSH data available.


Related in: MedlinePlus

Evolution of the BDI score over time by group.
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Related In: Results  -  Collection


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fig2: Evolution of the BDI score over time by group.

Mentions: The results showed that the evolution of the BDI scores over time between groups was significant in a nonlinear trend (P value nonlinear trend = 0.001). The effect size of this contrast was moderate (d′ = 0.55) in the short term (posttest) and smaller (d′ = 0.18) in the long term (at 9 months of follow-up). Figure 2 shows the evolution of the BDI score over time by groups.


Evaluation of the Effectiveness of a Psychoeducational Intervention in Treatment-Naïve Patients with Antidepressant Medication in Primary Care: A Randomized Controlled Trial.

Casañas R, Catalán R, Penadés R, Real J, Valero S, Muñoz M, Lalucat-Jo L, Casas M - ScientificWorldJournal (2015)

Evolution of the BDI score over time by group.
© Copyright Policy - open-access
Related In: Results  -  Collection

Show All Figures
getmorefigures.php?uid=PMC4562075&req=5

fig2: Evolution of the BDI score over time by group.
Mentions: The results showed that the evolution of the BDI scores over time between groups was significant in a nonlinear trend (P value nonlinear trend = 0.001). The effect size of this contrast was moderate (d′ = 0.55) in the short term (posttest) and smaller (d′ = 0.18) in the long term (at 9 months of follow-up). Figure 2 shows the evolution of the BDI score over time by groups.

Bottom Line: The analysis only showed significant differences in the BDI score posttreatment (P = 0.008; effect size Cohen's d' = 0.55).The PE intervention is an effective treatment in the depressive population not treated with AD medication.Before taking an AD, psychoeducational intervention should be considered.

View Article: PubMed Central - PubMed

Affiliation: Research Department, Centre Higiene Mental (CHM) Les Corts, C/Numancia, 103-105 Bajos, 08029 Barcelona, Spain ; Psychiatry and Legal Medicine Department, Universidad Autónoma de Barcelona, Barcelona, Spain ; Primary Healthcare University Research Institute IDIAP-Jordi Gol, Institut Català de la Salut (ICS), C/Sardenya 375, 08036 Barcelona, Spain.

ABSTRACT

Background: There is evidence supporting the effectiveness of psychoeducation (PE) in patients with symptoms of depression in primary care (PC), but very few studies have assessed this intervention in antidepressant-naïve patients. The aim of this study is to assess the effectiveness of a PE program in these patients, since the use of antidepressant (AD) medication may interfere with the effects of the intervention.

Methods: 106 participants were included, 50 from the PE program (12 weekly 1.5-hour sessions) and 56 from the control group (CG) that received the usual care. Patients were assessed at baseline and at 3, 6, and 9 months. The main outcome measures were the Beck Depression Inventory (BDI) and remission based on the BDI. The analysis was carried out on an intention-to-treat basis.

Results: The PE program group showed remission of symptoms of 40% (P = 0.001) posttreatment and 42% (P = 0.012) at 6 months. The analysis only showed significant differences in the BDI score posttreatment (P = 0.008; effect size Cohen's d' = 0.55).

Conclusions: The PE intervention is an effective treatment in the depressive population not treated with AD medication. Before taking an AD, psychoeducational intervention should be considered.

No MeSH data available.


Related in: MedlinePlus