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A Rare Case Report of Neurodegenerative Disease: Duchenne Muscular Dystrophy in Two Male Siblings.

Suneja B, Suneja ES, Adlakha VK, Chandna P - Int J Clin Pediatr Dent (2015)

Bottom Line: Clinically, it is characterized by progressive muscle wasting eventually leading to premature death.How to cite this article: Suneja B, Suneja ES, Adlakha VK, Chandna P.Int J Clin Pediatr Dent 2015;8(2):163-165.

View Article: PubMed Central - PubMed

Affiliation: Professor, Department of Pedodontics and Preventive Dentistry, BJS Dental College, Ludhiana, Punjab, India.

ABSTRACT
Duchenne muscular dystrophy (DMD) is an recessive X-linked mediated, musculoskeletal disorder that affects only males. It is the most common and severe form of muscular dystrophy where there is failure to manufacture dystrophin. Clinically, it is characterized by progressive muscle wasting eventually leading to premature death. This case report describes the genetic, oral and systemic findings in two cases of DMD in male siblings. How to cite this article: Suneja B, Suneja ES, Adlakha VK, Chandna P. A Rare Case Report of Neurodegenerative Disease: Duchenne Muscular Dystrophy in Two Male Siblings. Int J Clin Pediatr Dent 2015;8(2):163-165.

No MeSH data available.


Related in: MedlinePlus

Knee and hamstring contracture in the oldest sibling affected with DMD
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Figure 2: Knee and hamstring contracture in the oldest sibling affected with DMD

Mentions: On clinical examination, the oldest child presented with difficulty in standing, walking and stair climbing, obese appearance, proximal weakness, calf hypertrophy, and hamstring muscle contracture (Fig. 2). The other affected child presented with similar difficulty in stair climbing, muscle weakness and calf hypertrophy (Fig. 3). Dental findings in both affected children were open bite and enlarged tongue. Oral prophylaxis was performed for both affected children.


A Rare Case Report of Neurodegenerative Disease: Duchenne Muscular Dystrophy in Two Male Siblings.

Suneja B, Suneja ES, Adlakha VK, Chandna P - Int J Clin Pediatr Dent (2015)

Knee and hamstring contracture in the oldest sibling affected with DMD
© Copyright Policy - open-access
Related In: Results  -  Collection

License
Show All Figures
getmorefigures.php?uid=PMC4562054&req=5

Figure 2: Knee and hamstring contracture in the oldest sibling affected with DMD
Mentions: On clinical examination, the oldest child presented with difficulty in standing, walking and stair climbing, obese appearance, proximal weakness, calf hypertrophy, and hamstring muscle contracture (Fig. 2). The other affected child presented with similar difficulty in stair climbing, muscle weakness and calf hypertrophy (Fig. 3). Dental findings in both affected children were open bite and enlarged tongue. Oral prophylaxis was performed for both affected children.

Bottom Line: Clinically, it is characterized by progressive muscle wasting eventually leading to premature death.How to cite this article: Suneja B, Suneja ES, Adlakha VK, Chandna P.Int J Clin Pediatr Dent 2015;8(2):163-165.

View Article: PubMed Central - PubMed

Affiliation: Professor, Department of Pedodontics and Preventive Dentistry, BJS Dental College, Ludhiana, Punjab, India.

ABSTRACT
Duchenne muscular dystrophy (DMD) is an recessive X-linked mediated, musculoskeletal disorder that affects only males. It is the most common and severe form of muscular dystrophy where there is failure to manufacture dystrophin. Clinically, it is characterized by progressive muscle wasting eventually leading to premature death. This case report describes the genetic, oral and systemic findings in two cases of DMD in male siblings. How to cite this article: Suneja B, Suneja ES, Adlakha VK, Chandna P. A Rare Case Report of Neurodegenerative Disease: Duchenne Muscular Dystrophy in Two Male Siblings. Int J Clin Pediatr Dent 2015;8(2):163-165.

No MeSH data available.


Related in: MedlinePlus