Limits...
A Rare Case Report of Neurodegenerative Disease: Duchenne Muscular Dystrophy in Two Male Siblings.

Suneja B, Suneja ES, Adlakha VK, Chandna P - Int J Clin Pediatr Dent (2015)

Bottom Line: Clinically, it is characterized by progressive muscle wasting eventually leading to premature death.How to cite this article: Suneja B, Suneja ES, Adlakha VK, Chandna P.Int J Clin Pediatr Dent 2015;8(2):163-165.

View Article: PubMed Central - PubMed

Affiliation: Professor, Department of Pedodontics and Preventive Dentistry, BJS Dental College, Ludhiana, Punjab, India.

ABSTRACT
Duchenne muscular dystrophy (DMD) is an recessive X-linked mediated, musculoskeletal disorder that affects only males. It is the most common and severe form of muscular dystrophy where there is failure to manufacture dystrophin. Clinically, it is characterized by progressive muscle wasting eventually leading to premature death. This case report describes the genetic, oral and systemic findings in two cases of DMD in male siblings. How to cite this article: Suneja B, Suneja ES, Adlakha VK, Chandna P. A Rare Case Report of Neurodegenerative Disease: Duchenne Muscular Dystrophy in Two Male Siblings. Int J Clin Pediatr Dent 2015;8(2):163-165.

No MeSH data available.


Related in: MedlinePlus

Three male siblings of a family, of which two older children are affected with DMD
© Copyright Policy - open-access
Related In: Results  -  Collection

License
getmorefigures.php?uid=PMC4562054&req=5

Figure 1: Three male siblings of a family, of which two older children are affected with DMD

Mentions: Two boys aged 7 and 5 years were brought to a private dental clinic in Meerut, Uttar Pradesh, India for dental treatment. They are a family with three boys (Fig. 1). The two older children aged 7 and 5 years had been diagnosed with DMD at the age of 5 and 3 years respectively. Their parents gave a history of repeated falls, fatigue and inability to climb stairs and muscle weakness for both affected children. Their intelligence quotient (IQ) was in the normal range. The third and youngest child was 3 years old and yet unaffected.


A Rare Case Report of Neurodegenerative Disease: Duchenne Muscular Dystrophy in Two Male Siblings.

Suneja B, Suneja ES, Adlakha VK, Chandna P - Int J Clin Pediatr Dent (2015)

Three male siblings of a family, of which two older children are affected with DMD
© Copyright Policy - open-access
Related In: Results  -  Collection

License
Show All Figures
getmorefigures.php?uid=PMC4562054&req=5

Figure 1: Three male siblings of a family, of which two older children are affected with DMD
Mentions: Two boys aged 7 and 5 years were brought to a private dental clinic in Meerut, Uttar Pradesh, India for dental treatment. They are a family with three boys (Fig. 1). The two older children aged 7 and 5 years had been diagnosed with DMD at the age of 5 and 3 years respectively. Their parents gave a history of repeated falls, fatigue and inability to climb stairs and muscle weakness for both affected children. Their intelligence quotient (IQ) was in the normal range. The third and youngest child was 3 years old and yet unaffected.

Bottom Line: Clinically, it is characterized by progressive muscle wasting eventually leading to premature death.How to cite this article: Suneja B, Suneja ES, Adlakha VK, Chandna P.Int J Clin Pediatr Dent 2015;8(2):163-165.

View Article: PubMed Central - PubMed

Affiliation: Professor, Department of Pedodontics and Preventive Dentistry, BJS Dental College, Ludhiana, Punjab, India.

ABSTRACT
Duchenne muscular dystrophy (DMD) is an recessive X-linked mediated, musculoskeletal disorder that affects only males. It is the most common and severe form of muscular dystrophy where there is failure to manufacture dystrophin. Clinically, it is characterized by progressive muscle wasting eventually leading to premature death. This case report describes the genetic, oral and systemic findings in two cases of DMD in male siblings. How to cite this article: Suneja B, Suneja ES, Adlakha VK, Chandna P. A Rare Case Report of Neurodegenerative Disease: Duchenne Muscular Dystrophy in Two Male Siblings. Int J Clin Pediatr Dent 2015;8(2):163-165.

No MeSH data available.


Related in: MedlinePlus