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Sclerosing Sromal Tumor of the Ovary in Postmenopausal Women: A Report of Two Cases.

Lee CM, Lim S, Cho HY, Lee JS, Shin JW - J Menopausal Med (2015)

Bottom Line: Sclerosing stromal tumor (SST) was first delineated as a distinct ovarian sex cord stromal tumor in 1973 by Chalvardjian and Scully.We discovered two rare cases of SST in post-menopausal women which are the topic of this report.These case studies are accompanied by a brief review of the literature.

View Article: PubMed Central - PubMed

Affiliation: Department of Obstetrics and Gynecology, Gachon University Gil Hospital, Incheon, Korea.

ABSTRACT
Sclerosing stromal tumor (SST) was first delineated as a distinct ovarian sex cord stromal tumor in 1973 by Chalvardjian and Scully. It is a benign neoplasm, distinguished from other ovarian stromal tumors by the production of collagen and a pseudolobular pattern, and it tends to occur in the second and third decades of life in diagnosed patients. We discovered two rare cases of SST in post-menopausal women which are the topic of this report. These case studies are accompanied by a brief review of the literature.

No MeSH data available.


Related in: MedlinePlus

Microscopic features of the sclerosing stromal tumor from case 2. (A) The solid area includes a pseudolobular pattern of alternating hypercellular and hypocellular areas (H&E, × 40). (B) The cellular areas are composed of dual cell populations: collagen-producing spindle cells and rounded weak lutein cells (arrow) (H&E, × 400).
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Figure 3: Microscopic features of the sclerosing stromal tumor from case 2. (A) The solid area includes a pseudolobular pattern of alternating hypercellular and hypocellular areas (H&E, × 40). (B) The cellular areas are composed of dual cell populations: collagen-producing spindle cells and rounded weak lutein cells (arrow) (H&E, × 400).

Mentions: Microscopically evaluated, the solid area showed a pseudolobular pattern alternating between hypercellular and hypocellular areas (Fig. 3A). The cellular areas were composed of dual cell populations: collagen-producing spindle cells and rounded weak lutein cells (Fig. 3B). The results of the IHC assessment included Inhibin α: Focal positive, Calretinin: Positive, Smooth muscle actin: positive, desmin: focal weak positive and CD34: negative. The pathological diagnosis was SST of the left ovary.


Sclerosing Sromal Tumor of the Ovary in Postmenopausal Women: A Report of Two Cases.

Lee CM, Lim S, Cho HY, Lee JS, Shin JW - J Menopausal Med (2015)

Microscopic features of the sclerosing stromal tumor from case 2. (A) The solid area includes a pseudolobular pattern of alternating hypercellular and hypocellular areas (H&E, × 40). (B) The cellular areas are composed of dual cell populations: collagen-producing spindle cells and rounded weak lutein cells (arrow) (H&E, × 400).
© Copyright Policy - open-access
Related In: Results  -  Collection

License
Show All Figures
getmorefigures.php?uid=PMC4561739&req=5

Figure 3: Microscopic features of the sclerosing stromal tumor from case 2. (A) The solid area includes a pseudolobular pattern of alternating hypercellular and hypocellular areas (H&E, × 40). (B) The cellular areas are composed of dual cell populations: collagen-producing spindle cells and rounded weak lutein cells (arrow) (H&E, × 400).
Mentions: Microscopically evaluated, the solid area showed a pseudolobular pattern alternating between hypercellular and hypocellular areas (Fig. 3A). The cellular areas were composed of dual cell populations: collagen-producing spindle cells and rounded weak lutein cells (Fig. 3B). The results of the IHC assessment included Inhibin α: Focal positive, Calretinin: Positive, Smooth muscle actin: positive, desmin: focal weak positive and CD34: negative. The pathological diagnosis was SST of the left ovary.

Bottom Line: Sclerosing stromal tumor (SST) was first delineated as a distinct ovarian sex cord stromal tumor in 1973 by Chalvardjian and Scully.We discovered two rare cases of SST in post-menopausal women which are the topic of this report.These case studies are accompanied by a brief review of the literature.

View Article: PubMed Central - PubMed

Affiliation: Department of Obstetrics and Gynecology, Gachon University Gil Hospital, Incheon, Korea.

ABSTRACT
Sclerosing stromal tumor (SST) was first delineated as a distinct ovarian sex cord stromal tumor in 1973 by Chalvardjian and Scully. It is a benign neoplasm, distinguished from other ovarian stromal tumors by the production of collagen and a pseudolobular pattern, and it tends to occur in the second and third decades of life in diagnosed patients. We discovered two rare cases of SST in post-menopausal women which are the topic of this report. These case studies are accompanied by a brief review of the literature.

No MeSH data available.


Related in: MedlinePlus