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Sclerosing Sromal Tumor of the Ovary in Postmenopausal Women: A Report of Two Cases.

Lee CM, Lim S, Cho HY, Lee JS, Shin JW - J Menopausal Med (2015)

Bottom Line: Sclerosing stromal tumor (SST) was first delineated as a distinct ovarian sex cord stromal tumor in 1973 by Chalvardjian and Scully.We discovered two rare cases of SST in post-menopausal women which are the topic of this report.These case studies are accompanied by a brief review of the literature.

View Article: PubMed Central - PubMed

Affiliation: Department of Obstetrics and Gynecology, Gachon University Gil Hospital, Incheon, Korea.

ABSTRACT
Sclerosing stromal tumor (SST) was first delineated as a distinct ovarian sex cord stromal tumor in 1973 by Chalvardjian and Scully. It is a benign neoplasm, distinguished from other ovarian stromal tumors by the production of collagen and a pseudolobular pattern, and it tends to occur in the second and third decades of life in diagnosed patients. We discovered two rare cases of SST in post-menopausal women which are the topic of this report. These case studies are accompanied by a brief review of the literature.

No MeSH data available.


Related in: MedlinePlus

Microscopic features of the sclerosing stromal tumor from case 1. (A) The vessels have a hemangiopericytoma-like staghorn pattern (H&E, × 400). (B) The luteinized cells are strongly immunoreactive for inhibin-alpha (× 200).
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Figure 1: Microscopic features of the sclerosing stromal tumor from case 1. (A) The vessels have a hemangiopericytoma-like staghorn pattern (H&E, × 400). (B) The luteinized cells are strongly immunoreactive for inhibin-alpha (× 200).

Mentions: A gross examination revealed a 17.5 × 14.5 × 9.0 cm mass weighing 1248 g on the left ovary. Upon sectioning, the mass was found to be cystic with hemorrhagic fluid and a solid portion. Microscopically, the vessels contained a hemangiopericytoma-like staghorn pattern (Fig. 1A). The luteinized cells were strongly immunoreactive for inhibin alpha (Fig. 1B). The immunohistochemistry (IHC) results included inhibin α: positive, CD99: positive, desmin: positive, and actin: positive. Based on these histomorphologic findings, the diagnosis was SST.


Sclerosing Sromal Tumor of the Ovary in Postmenopausal Women: A Report of Two Cases.

Lee CM, Lim S, Cho HY, Lee JS, Shin JW - J Menopausal Med (2015)

Microscopic features of the sclerosing stromal tumor from case 1. (A) The vessels have a hemangiopericytoma-like staghorn pattern (H&E, × 400). (B) The luteinized cells are strongly immunoreactive for inhibin-alpha (× 200).
© Copyright Policy - open-access
Related In: Results  -  Collection

License
Show All Figures
getmorefigures.php?uid=PMC4561739&req=5

Figure 1: Microscopic features of the sclerosing stromal tumor from case 1. (A) The vessels have a hemangiopericytoma-like staghorn pattern (H&E, × 400). (B) The luteinized cells are strongly immunoreactive for inhibin-alpha (× 200).
Mentions: A gross examination revealed a 17.5 × 14.5 × 9.0 cm mass weighing 1248 g on the left ovary. Upon sectioning, the mass was found to be cystic with hemorrhagic fluid and a solid portion. Microscopically, the vessels contained a hemangiopericytoma-like staghorn pattern (Fig. 1A). The luteinized cells were strongly immunoreactive for inhibin alpha (Fig. 1B). The immunohistochemistry (IHC) results included inhibin α: positive, CD99: positive, desmin: positive, and actin: positive. Based on these histomorphologic findings, the diagnosis was SST.

Bottom Line: Sclerosing stromal tumor (SST) was first delineated as a distinct ovarian sex cord stromal tumor in 1973 by Chalvardjian and Scully.We discovered two rare cases of SST in post-menopausal women which are the topic of this report.These case studies are accompanied by a brief review of the literature.

View Article: PubMed Central - PubMed

Affiliation: Department of Obstetrics and Gynecology, Gachon University Gil Hospital, Incheon, Korea.

ABSTRACT
Sclerosing stromal tumor (SST) was first delineated as a distinct ovarian sex cord stromal tumor in 1973 by Chalvardjian and Scully. It is a benign neoplasm, distinguished from other ovarian stromal tumors by the production of collagen and a pseudolobular pattern, and it tends to occur in the second and third decades of life in diagnosed patients. We discovered two rare cases of SST in post-menopausal women which are the topic of this report. These case studies are accompanied by a brief review of the literature.

No MeSH data available.


Related in: MedlinePlus