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Frequency of Human Papilloma Virus (HPV) subtypes 31,33,35,39 and 45 among Yemeni women with cervical cancer.

Ahmed HG, Bensumaidea SH, Ashankyty IM - Infect. Agents Cancer (2015)

Bottom Line: A total of 200 (150 malignant and 50 benign) tissue samples were obtained from Yemeni women with cervical cancer, were investigated for the presence of HPV subtypes 31,33,35,39 and 45 by Polymerase Chain Reaction (PCR).The frequency of these HPV subtypes among Yemeni women with cervical cancer was 24 %.HPV 31, HPV 33, HPV35, HPV 39 and HPV45 were prevalent among Yemeni women with cervical cancer.

View Article: PubMed Central - PubMed

Affiliation: Molecular Diagnostics and Personalized Therapeutics Unit, University of Ha'il, Ha'il, Kingdom of Saudi Arabia ; Department of Pathology, College of Medicine, University of Ha'il, 2240 Hai'l, Kingdom of Saudi Arabia ; Department of Histopathology and Cytology, FMLS, University of Khartoum, Khartoum, Sudan.

ABSTRACT

Background: Identification of different HPV subtypes in unidentified communities provides sufficient information for screening and monitoring potential impact of a vaccination program. Therefore, the aim of this study was to screen for the presence of HPVs subtypes 31,33,35,39 and 45 among Yemeni women with Cervical Cancer.

Methodology: A total of 200 (150 malignant and 50 benign) tissue samples were obtained from Yemeni women with cervical cancer, were investigated for the presence of HPV subtypes 31,33,35,39 and 45 by Polymerase Chain Reaction (PCR).

Results: Of the 150 cervical cancer tissue specimens, HPV 31, HPV 33, HPV35, HPV 39 and HPV45 were identified in 10/150 (6.7 %), 6/150 (4 %), 6/150 (4 %), 5/150 (3.3 %) and 10/150 (6.7 %), respectively. The frequency of these HPV subtypes among Yemeni women with cervical cancer was 24 %.

Conclusion: HPV 31, HPV 33, HPV35, HPV 39 and HPV45 were prevalent among Yemeni women with cervical cancer.

No MeSH data available.


Related in: MedlinePlus

Description of the study population by HPV infection and residence
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Fig3: Description of the study population by HPV infection and residence

Mentions: With respect to the residence, most of cases of Cervical Cancer were coming from Al-Janad representing 52/200 (26 %) followed by Aden constituting 45/200 (22.5 %), as shown in Fig. 3. In regard to the residence and HPV infection, the great majority of infections were identified among Al-Janad populations, representing 14/43 (32.6 %) followed by Aden, Azaal, Tohama Hadhramout and Saba’a, constituting 11/43 (25.6 %), 8/43 (18.6 %), 4/43 (9.3 %), 3/43 (7 %) and 3/43 (7 %), respectively, as shown in Table 4, Fig. 3. However, when calculating the percentage within individual entire residence, the highest proportion of infection was found in the Saba’a representing 33.3 % followed by Al-Janad, Aden, Azaal, Tohama and Hadhramout constituting 27, 24.4, 20, 16.7 and 10 %, in this order, as indicated in Fig. 4.Fig. 3


Frequency of Human Papilloma Virus (HPV) subtypes 31,33,35,39 and 45 among Yemeni women with cervical cancer.

Ahmed HG, Bensumaidea SH, Ashankyty IM - Infect. Agents Cancer (2015)

Description of the study population by HPV infection and residence
© Copyright Policy - OpenAccess
Related In: Results  -  Collection

License 1 - License 2
Show All Figures
getmorefigures.php?uid=PMC4561418&req=5

Fig3: Description of the study population by HPV infection and residence
Mentions: With respect to the residence, most of cases of Cervical Cancer were coming from Al-Janad representing 52/200 (26 %) followed by Aden constituting 45/200 (22.5 %), as shown in Fig. 3. In regard to the residence and HPV infection, the great majority of infections were identified among Al-Janad populations, representing 14/43 (32.6 %) followed by Aden, Azaal, Tohama Hadhramout and Saba’a, constituting 11/43 (25.6 %), 8/43 (18.6 %), 4/43 (9.3 %), 3/43 (7 %) and 3/43 (7 %), respectively, as shown in Table 4, Fig. 3. However, when calculating the percentage within individual entire residence, the highest proportion of infection was found in the Saba’a representing 33.3 % followed by Al-Janad, Aden, Azaal, Tohama and Hadhramout constituting 27, 24.4, 20, 16.7 and 10 %, in this order, as indicated in Fig. 4.Fig. 3

Bottom Line: A total of 200 (150 malignant and 50 benign) tissue samples were obtained from Yemeni women with cervical cancer, were investigated for the presence of HPV subtypes 31,33,35,39 and 45 by Polymerase Chain Reaction (PCR).The frequency of these HPV subtypes among Yemeni women with cervical cancer was 24 %.HPV 31, HPV 33, HPV35, HPV 39 and HPV45 were prevalent among Yemeni women with cervical cancer.

View Article: PubMed Central - PubMed

Affiliation: Molecular Diagnostics and Personalized Therapeutics Unit, University of Ha'il, Ha'il, Kingdom of Saudi Arabia ; Department of Pathology, College of Medicine, University of Ha'il, 2240 Hai'l, Kingdom of Saudi Arabia ; Department of Histopathology and Cytology, FMLS, University of Khartoum, Khartoum, Sudan.

ABSTRACT

Background: Identification of different HPV subtypes in unidentified communities provides sufficient information for screening and monitoring potential impact of a vaccination program. Therefore, the aim of this study was to screen for the presence of HPVs subtypes 31,33,35,39 and 45 among Yemeni women with Cervical Cancer.

Methodology: A total of 200 (150 malignant and 50 benign) tissue samples were obtained from Yemeni women with cervical cancer, were investigated for the presence of HPV subtypes 31,33,35,39 and 45 by Polymerase Chain Reaction (PCR).

Results: Of the 150 cervical cancer tissue specimens, HPV 31, HPV 33, HPV35, HPV 39 and HPV45 were identified in 10/150 (6.7 %), 6/150 (4 %), 6/150 (4 %), 5/150 (3.3 %) and 10/150 (6.7 %), respectively. The frequency of these HPV subtypes among Yemeni women with cervical cancer was 24 %.

Conclusion: HPV 31, HPV 33, HPV35, HPV 39 and HPV45 were prevalent among Yemeni women with cervical cancer.

No MeSH data available.


Related in: MedlinePlus