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Determining factors of diuresis in chronic kidney disease patients initiating hemodialysis.

Nechita AM, Rădulescu D, Peride I, Niculae A, Bratu O, Ferechide D, Ciocâlteu A, Checheriță IA, Mischianu D - J Med Life (2015 Jul-Sep)

Bottom Line: Glomerular etiology, cardiac systolic dysfunction, severe malnutrition, emergency dialysis initiation and lack of permanent vascular access were proved to be associated with significant low diuresis.Age, gender, estimated glomerular filtration rate (GFR) and the presence of systemic hypertension did not influence the amount of daily diuresis.Factors influencing residual diuresis may be distinct from those that influence residual GFR.

View Article: PubMed Central - PubMed

Affiliation: Department of Nephrology and Dialysis, "Sf. Ioan" Clinical Emergency Hospital, Bucharest, Romania.

ABSTRACT

Background: Patients with stage 5 chronic kidney disease (CKD) begin chronic hemodialysis with variable diuresis levels correlated to a comparable low glomerular filtration rate. Residual diuresis influences long-term evolution of the hemodialyzed patient, modifying the prognosis even if optimal Kt/ V is achieved.

Aim of the study: The present study emphasizes the main determining factors of diuresis in a cohort of stage 5 CKD subjects at the beginning of hemodialysis.

Material and methods: 216 patients with stage 5 CKD starting chronic hemodialysis were included in the study, and were grouped according to their residual diuresis: group A (urine output ≤ 500 mL/ day); group B (urine output between 500-1200 mL/ day); group C (urine output ≥ 1200 mL/ day).

Results: Glomerular etiology, cardiac systolic dysfunction, severe malnutrition, emergency dialysis initiation and lack of permanent vascular access were proved to be associated with significant low diuresis. Age, gender, estimated glomerular filtration rate (GFR) and the presence of systemic hypertension did not influence the amount of daily diuresis.

Conclusions: In CKD stage 5 patients, residual diuresis presents large variations in conditions of comparable low GFR. Factors influencing residual diuresis may be distinct from those that influence residual GFR.

No MeSH data available.


Related in: MedlinePlus

Average diuresis depending on the type of vascular access
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Figure 7: Average diuresis depending on the type of vascular access

Mentions: Patients having already a mature vascular access at the time of HD initiation were proved to have a better urine volume preservation when compared with those beginning hemodialysis on temporary catheters (T test, p = 0.00006) – Fig. 7.


Determining factors of diuresis in chronic kidney disease patients initiating hemodialysis.

Nechita AM, Rădulescu D, Peride I, Niculae A, Bratu O, Ferechide D, Ciocâlteu A, Checheriță IA, Mischianu D - J Med Life (2015 Jul-Sep)

Average diuresis depending on the type of vascular access
© Copyright Policy - open-access
Related In: Results  -  Collection

License
Show All Figures
getmorefigures.php?uid=PMC4556923&req=5

Figure 7: Average diuresis depending on the type of vascular access
Mentions: Patients having already a mature vascular access at the time of HD initiation were proved to have a better urine volume preservation when compared with those beginning hemodialysis on temporary catheters (T test, p = 0.00006) – Fig. 7.

Bottom Line: Glomerular etiology, cardiac systolic dysfunction, severe malnutrition, emergency dialysis initiation and lack of permanent vascular access were proved to be associated with significant low diuresis.Age, gender, estimated glomerular filtration rate (GFR) and the presence of systemic hypertension did not influence the amount of daily diuresis.Factors influencing residual diuresis may be distinct from those that influence residual GFR.

View Article: PubMed Central - PubMed

Affiliation: Department of Nephrology and Dialysis, "Sf. Ioan" Clinical Emergency Hospital, Bucharest, Romania.

ABSTRACT

Background: Patients with stage 5 chronic kidney disease (CKD) begin chronic hemodialysis with variable diuresis levels correlated to a comparable low glomerular filtration rate. Residual diuresis influences long-term evolution of the hemodialyzed patient, modifying the prognosis even if optimal Kt/ V is achieved.

Aim of the study: The present study emphasizes the main determining factors of diuresis in a cohort of stage 5 CKD subjects at the beginning of hemodialysis.

Material and methods: 216 patients with stage 5 CKD starting chronic hemodialysis were included in the study, and were grouped according to their residual diuresis: group A (urine output ≤ 500 mL/ day); group B (urine output between 500-1200 mL/ day); group C (urine output ≥ 1200 mL/ day).

Results: Glomerular etiology, cardiac systolic dysfunction, severe malnutrition, emergency dialysis initiation and lack of permanent vascular access were proved to be associated with significant low diuresis. Age, gender, estimated glomerular filtration rate (GFR) and the presence of systemic hypertension did not influence the amount of daily diuresis.

Conclusions: In CKD stage 5 patients, residual diuresis presents large variations in conditions of comparable low GFR. Factors influencing residual diuresis may be distinct from those that influence residual GFR.

No MeSH data available.


Related in: MedlinePlus