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Mental illness, challenging behaviour, and psychotropic drug prescribing in people with intellectual disability: UK population based cohort study.

Sheehan R, Hassiotis A, Walters K, Osborn D, Strydom A, Horsfall L - BMJ (2015)

Bottom Line: New prescriptions of mood stabilisers also decreased significantly.The rate of new antipsychotic prescribing was significantly higher in people with challenging behaviour (incidence rate ratio 2.08, 95% confidence interval 1.90 to 2.27; P<0.001), autism (1.79, 1.56 to 2.04; P<0.001), and dementia (1.42, 1.12 to 1.81; P<0.003) and in those of older age, after control for other sociodemographic factors and comorbidity.More evidence is needed of the efficacy and safety of psychotropic drugs in this group, particularly when they are used for challenging behaviour.

View Article: PubMed Central - PubMed

Affiliation: Division of Psychiatry, University College London, London W1T 7NF, UK r.sheehan@ucl.ac.uk.

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Fig 1 Time trends in new recording of mental illness and challenging behaviour in adults with intellectual disability in UK primary care, 1999-2013
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fig1: Fig 1 Time trends in new recording of mental illness and challenging behaviour in adults with intellectual disability in UK primary care, 1999-2013

Mentions: Analysis of time trends in the recording of severe mental illness showed a gradual decline in the rate of recording by 5% (95% confidence interval 3% to 7%) per year between 1999 and 2013 (P<0.001), after adjustment for changes in age and sex of the cohort (fig 1). Rates of recording of depression and anxiety did not change.


Mental illness, challenging behaviour, and psychotropic drug prescribing in people with intellectual disability: UK population based cohort study.

Sheehan R, Hassiotis A, Walters K, Osborn D, Strydom A, Horsfall L - BMJ (2015)

Fig 1 Time trends in new recording of mental illness and challenging behaviour in adults with intellectual disability in UK primary care, 1999-2013
© Copyright Policy - open-access
Related In: Results  -  Collection

License
Show All Figures
getmorefigures.php?uid=PMC4556752&req=5

fig1: Fig 1 Time trends in new recording of mental illness and challenging behaviour in adults with intellectual disability in UK primary care, 1999-2013
Mentions: Analysis of time trends in the recording of severe mental illness showed a gradual decline in the rate of recording by 5% (95% confidence interval 3% to 7%) per year between 1999 and 2013 (P<0.001), after adjustment for changes in age and sex of the cohort (fig 1). Rates of recording of depression and anxiety did not change.

Bottom Line: New prescriptions of mood stabilisers also decreased significantly.The rate of new antipsychotic prescribing was significantly higher in people with challenging behaviour (incidence rate ratio 2.08, 95% confidence interval 1.90 to 2.27; P<0.001), autism (1.79, 1.56 to 2.04; P<0.001), and dementia (1.42, 1.12 to 1.81; P<0.003) and in those of older age, after control for other sociodemographic factors and comorbidity.More evidence is needed of the efficacy and safety of psychotropic drugs in this group, particularly when they are used for challenging behaviour.

View Article: PubMed Central - PubMed

Affiliation: Division of Psychiatry, University College London, London W1T 7NF, UK r.sheehan@ucl.ac.uk.

Show MeSH
Related in: MedlinePlus