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Avian influenza A (H5N1) infection with respiratory failure and meningoencephalitis in a Canadian traveller.

Rajabali N, Lim T, Sokolowski C, Prevost JD, Lee EZ - Can J Infect Dis Med Microbiol (2015 Jul-Aug)

Bottom Line: In an urban centre in Alberta, an otherwise healthy 28-year-old woman presented to hospital with pleuritic chest and abdominal pain after returning from Beijing, China.After several days, this was followed by headache, confusion and, ultimately, respiratory failure, coma and death.Abstract available from the publisher.

View Article: PubMed Central - PubMed

Affiliation: University of Alberta, Edmonton;

ABSTRACT
In an urban centre in Alberta, an otherwise healthy 28-year-old woman presented to hospital with pleuritic chest and abdominal pain after returning from Beijing, China. After several days, this was followed by headache, confusion and, ultimately, respiratory failure, coma and death. Microbiology yielded influenza A subtype H5N1 from various body sites and neuroimaging was consistent with meningoencephalitis. While H5N1 infections in humans have been reported in Asia since 1997, this is the first documented case of H5N1 influenza in the Western Hemisphere. The present case demonstrated the typical manifestation of H5N1 influenza but, for the first time, also confirmed previous suggestions from human and animal studies that H5N1 is neurotropic and can manifest with neurological symptoms and meningoencephalitis.

No MeSH data available.


Related in: MedlinePlus

Computed tomography scan of the head demonstrating generalized cerebral parenchymal swelling, diffuse sulcal space and cisternal space effacement suggestive of meningoencephalitis
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f2-jidmm-26-221: Computed tomography scan of the head demonstrating generalized cerebral parenchymal swelling, diffuse sulcal space and cisternal space effacement suggestive of meningoencephalitis

Mentions: A nonenhanced computed tomography scan of the head (Figure 2) demonstrated generalized cerebral parenchymal swelling, diffuse sulcal space and cisternal space effacement suggestive of meningoencephalitis.


Avian influenza A (H5N1) infection with respiratory failure and meningoencephalitis in a Canadian traveller.

Rajabali N, Lim T, Sokolowski C, Prevost JD, Lee EZ - Can J Infect Dis Med Microbiol (2015 Jul-Aug)

Computed tomography scan of the head demonstrating generalized cerebral parenchymal swelling, diffuse sulcal space and cisternal space effacement suggestive of meningoencephalitis
© Copyright Policy
Related In: Results  -  Collection

License
Show All Figures
getmorefigures.php?uid=PMC4556185&req=5

f2-jidmm-26-221: Computed tomography scan of the head demonstrating generalized cerebral parenchymal swelling, diffuse sulcal space and cisternal space effacement suggestive of meningoencephalitis
Mentions: A nonenhanced computed tomography scan of the head (Figure 2) demonstrated generalized cerebral parenchymal swelling, diffuse sulcal space and cisternal space effacement suggestive of meningoencephalitis.

Bottom Line: In an urban centre in Alberta, an otherwise healthy 28-year-old woman presented to hospital with pleuritic chest and abdominal pain after returning from Beijing, China.After several days, this was followed by headache, confusion and, ultimately, respiratory failure, coma and death.Abstract available from the publisher.

View Article: PubMed Central - PubMed

Affiliation: University of Alberta, Edmonton;

ABSTRACT
In an urban centre in Alberta, an otherwise healthy 28-year-old woman presented to hospital with pleuritic chest and abdominal pain after returning from Beijing, China. After several days, this was followed by headache, confusion and, ultimately, respiratory failure, coma and death. Microbiology yielded influenza A subtype H5N1 from various body sites and neuroimaging was consistent with meningoencephalitis. While H5N1 infections in humans have been reported in Asia since 1997, this is the first documented case of H5N1 influenza in the Western Hemisphere. The present case demonstrated the typical manifestation of H5N1 influenza but, for the first time, also confirmed previous suggestions from human and animal studies that H5N1 is neurotropic and can manifest with neurological symptoms and meningoencephalitis.

No MeSH data available.


Related in: MedlinePlus