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Psammous desmo-osteoblastoma with concomitant aneurysmal bone cyst of mandible.

Shruthi SK, Kamath VV, Hegde S, Sreevidya B - Ann Maxillofac Surg (2015 Jan-Jun)

Bottom Line: Aneurysmal bone cysts (ABCs) are known to be secondarily associated with primary osseous neoplasms like ossifying fibroma, giant cell granuloma, etc.The histological presentation substantiated by special stains and immunohistochemistry point to the diagnosis of psammous desmo-osteoblastoma with a concomitant ABC.Review of the literature revealed the presentation to be rare with very few cases reported till date.

View Article: PubMed Central - PubMed

Affiliation: Department of Oral and Maxillofacial Pathology, Dr. Syamala Reddy Dental College Hospital and Research Centre, Bengaluru, Karnataka, India.

ABSTRACT
Juvenile psammomatoid ossifying fibroma is a gradually progressive, aggressive extragnathic craniofacial tumor of bone. Due to its complex histogenesis, biological behavior, histology, and classification, its nomenclature has always been the focus of debate among pathologists. Based on the clinical behavior and histology, the term psammous desmo-osteoblastoma (PDO) is an apt expression for this lesion. Immunohistochemical investigation with anti-osteonectin shows positivity for spindle cells whereas psammoma bodies are negative. These results shore up the hypothesis of osteogenic differentiation of the undifferentiated mesenchymal cells of the periodontal ligament that may be responsible for the aggressive behavior of the lesion. Aneurysmal bone cysts (ABCs) are known to be secondarily associated with primary osseous neoplasms like ossifying fibroma, giant cell granuloma, etc. We report a rare case of PDO with concomitant ABC in the mandible of a 30-year-old male patient. The present lesion had recurred at the same site of an osteolytic lesion diagnosed 7 years ago as a benign fibro-osseous lesion and treated by conservative surgical curettage. The histological presentation substantiated by special stains and immunohistochemistry point to the diagnosis of psammous desmo-osteoblastoma with a concomitant ABC. Review of the literature revealed the presentation to be rare with very few cases reported till date.

No MeSH data available.


Related in: MedlinePlus

Preoperative photograph showing diffuse swelling of the lower one third of the Face
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Figure 1: Preoperative photograph showing diffuse swelling of the lower one third of the Face

Mentions: A 30-year-old male patient reported to the Oral and Maxillofacial Surgery Department with a complaint of swelling in left lower jaw since 1year [Figure 1]. Patient gave a history of similar asymptomatic hard swelling in the same site 7 years ago. Records revealed an unilocular osteolytic lesion in the left mandible extending from the mandibular canine region to the second molar causing expansion of the jaw involving the lower border of the mandible [Figure 2a]. A conservative surgical curettage was listed as having been done under general anesthesia and the pathological diagnosis was reported as a benign fibro-osseous lesion.


Psammous desmo-osteoblastoma with concomitant aneurysmal bone cyst of mandible.

Shruthi SK, Kamath VV, Hegde S, Sreevidya B - Ann Maxillofac Surg (2015 Jan-Jun)

Preoperative photograph showing diffuse swelling of the lower one third of the Face
© Copyright Policy - open-access
Related In: Results  -  Collection

License
Show All Figures
getmorefigures.php?uid=PMC4555939&req=5

Figure 1: Preoperative photograph showing diffuse swelling of the lower one third of the Face
Mentions: A 30-year-old male patient reported to the Oral and Maxillofacial Surgery Department with a complaint of swelling in left lower jaw since 1year [Figure 1]. Patient gave a history of similar asymptomatic hard swelling in the same site 7 years ago. Records revealed an unilocular osteolytic lesion in the left mandible extending from the mandibular canine region to the second molar causing expansion of the jaw involving the lower border of the mandible [Figure 2a]. A conservative surgical curettage was listed as having been done under general anesthesia and the pathological diagnosis was reported as a benign fibro-osseous lesion.

Bottom Line: Aneurysmal bone cysts (ABCs) are known to be secondarily associated with primary osseous neoplasms like ossifying fibroma, giant cell granuloma, etc.The histological presentation substantiated by special stains and immunohistochemistry point to the diagnosis of psammous desmo-osteoblastoma with a concomitant ABC.Review of the literature revealed the presentation to be rare with very few cases reported till date.

View Article: PubMed Central - PubMed

Affiliation: Department of Oral and Maxillofacial Pathology, Dr. Syamala Reddy Dental College Hospital and Research Centre, Bengaluru, Karnataka, India.

ABSTRACT
Juvenile psammomatoid ossifying fibroma is a gradually progressive, aggressive extragnathic craniofacial tumor of bone. Due to its complex histogenesis, biological behavior, histology, and classification, its nomenclature has always been the focus of debate among pathologists. Based on the clinical behavior and histology, the term psammous desmo-osteoblastoma (PDO) is an apt expression for this lesion. Immunohistochemical investigation with anti-osteonectin shows positivity for spindle cells whereas psammoma bodies are negative. These results shore up the hypothesis of osteogenic differentiation of the undifferentiated mesenchymal cells of the periodontal ligament that may be responsible for the aggressive behavior of the lesion. Aneurysmal bone cysts (ABCs) are known to be secondarily associated with primary osseous neoplasms like ossifying fibroma, giant cell granuloma, etc. We report a rare case of PDO with concomitant ABC in the mandible of a 30-year-old male patient. The present lesion had recurred at the same site of an osteolytic lesion diagnosed 7 years ago as a benign fibro-osseous lesion and treated by conservative surgical curettage. The histological presentation substantiated by special stains and immunohistochemistry point to the diagnosis of psammous desmo-osteoblastoma with a concomitant ABC. Review of the literature revealed the presentation to be rare with very few cases reported till date.

No MeSH data available.


Related in: MedlinePlus