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Multiple osteolytic lesions in a 14-year-old boy with HIV disease.

Murugan S - Indian J Sex Transm Dis (2015 Jan-Jun)

Bottom Line: Now the boy is on ART (ZDV + 3TC + EFV) since August 2013.His CD4 count improved and viral load became undetectable and he gained weight within 5 months of ART.Due to the rarity of its presentation, this case report is being reported.

View Article: PubMed Central - PubMed

Affiliation: Department of STD, SHIFA Hospitals, Tirunelveli, Tamil Nadu, India.

ABSTRACT
A 14 year old boy, said to have had multiple transfusions during infancy, was brought to the hospital for complaints of pain over right thigh for one week duration. MRI reveals multiple osteolytic lesions with enhancing hyperintense bone marrow lesions over iliac bones, right acetabulum and lumbar vertebral bodies and enlarged para-aortic, iliac and inguinal lymph nodes. CT of the whole body revealed osteolytic lesions on skull, mandible, right scapula, head of both humeri, L1 and L4 vertebrae, 5(th) and 10(th) ribs, both acetabulum and ala of sacrum along with enlargement of cervical, axillary and mesenteric, iliac and inguinal nodes. HIV ELISA was positive. Viral load was 141,700 copies/ml. CD4 count was 226 cells/mm(3). Multiple biopsy from the lesions and bone marrow revealed no evidence of tuberculosis and malignancy. Now the boy is on ART (ZDV + 3TC + EFV) since August 2013. His CD4 count improved and viral load became undetectable and he gained weight within 5 months of ART. Due to the rarity of its presentation, this case report is being reported.

No MeSH data available.


Related in: MedlinePlus

After antiretroviral therapy computed tomography 2
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Figure 4: After antiretroviral therapy computed tomography 2

Mentions: The boy was put on antiretroviral therapy (ART) (ZDV + 3TC + EFV) since August 2013 and he is doing well. Osteolytic changes improved with ART [Figure 4]. On March 2014, his viral load was reduced to undetectable level and his CD4 Count was 518 cells/cubic mm. He also gained 4 kg in 5 months.


Multiple osteolytic lesions in a 14-year-old boy with HIV disease.

Murugan S - Indian J Sex Transm Dis (2015 Jan-Jun)

After antiretroviral therapy computed tomography 2
© Copyright Policy - open-access
Related In: Results  -  Collection

License
Show All Figures
getmorefigures.php?uid=PMC4555912&req=5

Figure 4: After antiretroviral therapy computed tomography 2
Mentions: The boy was put on antiretroviral therapy (ART) (ZDV + 3TC + EFV) since August 2013 and he is doing well. Osteolytic changes improved with ART [Figure 4]. On March 2014, his viral load was reduced to undetectable level and his CD4 Count was 518 cells/cubic mm. He also gained 4 kg in 5 months.

Bottom Line: Now the boy is on ART (ZDV + 3TC + EFV) since August 2013.His CD4 count improved and viral load became undetectable and he gained weight within 5 months of ART.Due to the rarity of its presentation, this case report is being reported.

View Article: PubMed Central - PubMed

Affiliation: Department of STD, SHIFA Hospitals, Tirunelveli, Tamil Nadu, India.

ABSTRACT
A 14 year old boy, said to have had multiple transfusions during infancy, was brought to the hospital for complaints of pain over right thigh for one week duration. MRI reveals multiple osteolytic lesions with enhancing hyperintense bone marrow lesions over iliac bones, right acetabulum and lumbar vertebral bodies and enlarged para-aortic, iliac and inguinal lymph nodes. CT of the whole body revealed osteolytic lesions on skull, mandible, right scapula, head of both humeri, L1 and L4 vertebrae, 5(th) and 10(th) ribs, both acetabulum and ala of sacrum along with enlargement of cervical, axillary and mesenteric, iliac and inguinal nodes. HIV ELISA was positive. Viral load was 141,700 copies/ml. CD4 count was 226 cells/mm(3). Multiple biopsy from the lesions and bone marrow revealed no evidence of tuberculosis and malignancy. Now the boy is on ART (ZDV + 3TC + EFV) since August 2013. His CD4 count improved and viral load became undetectable and he gained weight within 5 months of ART. Due to the rarity of its presentation, this case report is being reported.

No MeSH data available.


Related in: MedlinePlus