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Pruritic papules on the vulva.

Amitha AA, Rao AC, Rao R - Indian J Sex Transm Dis (2015 Jan-Jun)

View Article: PubMed Central - PubMed

Affiliation: Department of Dermatology, Kasturba Medical College, Manipal University, Manipal, Karnataka, India.

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A 49-year-old woman was referred from the gynaecology clinic for the evaluation of vulval pruritus of 6-month duration... She observed periodic exacerbation of itching during menstrual cycles... Previous treatment with topical steroids and antifungal were ineffective in alleviating her symptoms... Genital examination revealed discrete, small (1–3 mm), firm, non-tender, yellowish brown papules on the labia majora bilaterally [Figure 1]... Their occurrence in the genital region is very rare; syringomas localized to the vulvar region can pose a diagnostic challenge to the clinician... Vulvar syringoma (VS) are frequently seen in association with extragenital lesions thus making it mandatory to examine the genital region in patients presenting with syringoma over the face or vice versa... Huang et al. in their series of 18 patients with VS have recorded itching in 72% of patients... It has been suggested that VS are hormone responsive as they may increase in size during pregnancy, premenstrual period or with the use of oral contraceptive pills... Immunohistochemistry studies have yielded conflicting results; few reports have shown the presence of estrogen and progesterone receptors while other reports have failed to confirm this finding... Histopathological examination will help to arrive at a diagnosis and should be done in all cases... There is no effective modality of treatment for VS... Topical atropine, tretinoin and oral tranilast have been tried in few patients with success... Physical modalities of treatment like cryotherapy or electro-cautery and surgical excision and full-thickness grafting have been recommended in few reports... Carbon dioxide laser has been found to be very useful in few patients.

No MeSH data available.


Yellowish-brown papules in the labia majora
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Figure 1: Yellowish-brown papules in the labia majora

Mentions: A 49-year-old woman was referred from the gynaecology clinic for the evaluation of vulval pruritus of 6-month duration. She observed periodic exacerbation of itching during menstrual cycles. Previous treatment with topical steroids and antifungal were ineffective in alleviating her symptoms. Genital examination revealed discrete, small (1–3 mm), firm, non-tender, yellowish brown papules on the labia majora bilaterally [Figure 1]. There was no evidence of similar lesions in other body parts.


Pruritic papules on the vulva.

Amitha AA, Rao AC, Rao R - Indian J Sex Transm Dis (2015 Jan-Jun)

Yellowish-brown papules in the labia majora
© Copyright Policy - open-access
Related In: Results  -  Collection

License
Show All Figures
getmorefigures.php?uid=PMC4555891&req=5

Figure 1: Yellowish-brown papules in the labia majora
Mentions: A 49-year-old woman was referred from the gynaecology clinic for the evaluation of vulval pruritus of 6-month duration. She observed periodic exacerbation of itching during menstrual cycles. Previous treatment with topical steroids and antifungal were ineffective in alleviating her symptoms. Genital examination revealed discrete, small (1–3 mm), firm, non-tender, yellowish brown papules on the labia majora bilaterally [Figure 1]. There was no evidence of similar lesions in other body parts.

View Article: PubMed Central - PubMed

Affiliation: Department of Dermatology, Kasturba Medical College, Manipal University, Manipal, Karnataka, India.

AUTOMATICALLY GENERATED EXCERPT
Please rate it.

A 49-year-old woman was referred from the gynaecology clinic for the evaluation of vulval pruritus of 6-month duration... She observed periodic exacerbation of itching during menstrual cycles... Previous treatment with topical steroids and antifungal were ineffective in alleviating her symptoms... Genital examination revealed discrete, small (1–3 mm), firm, non-tender, yellowish brown papules on the labia majora bilaterally [Figure 1]... Their occurrence in the genital region is very rare; syringomas localized to the vulvar region can pose a diagnostic challenge to the clinician... Vulvar syringoma (VS) are frequently seen in association with extragenital lesions thus making it mandatory to examine the genital region in patients presenting with syringoma over the face or vice versa... Huang et al. in their series of 18 patients with VS have recorded itching in 72% of patients... It has been suggested that VS are hormone responsive as they may increase in size during pregnancy, premenstrual period or with the use of oral contraceptive pills... Immunohistochemistry studies have yielded conflicting results; few reports have shown the presence of estrogen and progesterone receptors while other reports have failed to confirm this finding... Histopathological examination will help to arrive at a diagnosis and should be done in all cases... There is no effective modality of treatment for VS... Topical atropine, tretinoin and oral tranilast have been tried in few patients with success... Physical modalities of treatment like cryotherapy or electro-cautery and surgical excision and full-thickness grafting have been recommended in few reports... Carbon dioxide laser has been found to be very useful in few patients.

No MeSH data available.