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Long-Lasting Reduction of Blood Pressure by Electroacupuncture in Patients with Hypertension: Randomized Controlled Trial.

Li P, Tjen-A-Looi SC, Cheng L, Liu D, Painovich J, Vinjamury S, Longhurst JC - Med Acupunct (2015)

Bottom Line: Objective: To examine effectiveness of electroacupuncture (EA) at select acupoints to reduce systolic blood pressure (SBP) and diastolic blood pressures (DBP) in hypertensive patients.Results: After 8 weeks, 33 patients treated with EA at PC 5-6+ST 36-37 had decreased peak and average SBP and DBP, compared with 32 patients treated with EA at LI 6-7+GB 37-39 control acupoints.Conclusions: EA at select acupoints reduces blood pressure.

View Article: PubMed Central - PubMed

Affiliation: Susan-Samueli Center for Integrative Medicine, University of California , Irvine, School of Medicine, Irvine, CA.

ABSTRACT

Background: Acupuncture at specific acupoints has experimentally been found to reduce chronically elevated blood pressure. Objective: To examine effectiveness of electroacupuncture (EA) at select acupoints to reduce systolic blood pressure (SBP) and diastolic blood pressures (DBP) in hypertensive patients. Design: Two-arm parallel study. Patients: Sixty-five hypertensive patients not receiving medication were assigned randomly to one of the two acupuncture intervention (33 versus 32 patients). Intervention: Patients were assessed with 24-hour ambulatory blood pressure monitoring. They were treated with 30-minutes of EA at PC 5-6+ST 36-37 or LI 6-7+GB 37-39 once weekly for 8 weeks. Four acupuncturists provided single-blinded treatment. Main outcome measures: Primary outcomes measuring effectiveness of EA were peak and average SBP and DBP. Secondary outcomes examined underlying mechanisms of acupuncture with plasma norepinephrine, renin, and aldosterone before and after 8 weeks of treatment. Outcomes were obtained by double-blinded evaluation. Results: After 8 weeks, 33 patients treated with EA at PC 5-6+ST 36-37 had decreased peak and average SBP and DBP, compared with 32 patients treated with EA at LI 6-7+GB 37-39 control acupoints. Changes in blood pressures significantly differed between the two patient groups. In 14 patients, a long-lasting blood pressure-lowering acupuncture effect was observed for an additional 4 weeks of EA at PC 5-6+ST 36-37. After treatment, the plasma concentration of norepinephrine, which was initially elevated, was decreased by 41%; likewise, renin was decreased by 67% and aldosterone by 22%. Conclusions: EA at select acupoints reduces blood pressure. Sympathetic and renin-aldosterone systems were likely related to the long-lasting EA actions.

No MeSH data available.


Action of electroacupuncture over a 6-month period assessed during monthly reinforcement therapy in a subgroup of 7 hypertensive patients. After 8 weeks of weekly EA, continued monthly EA treatment maintained a low systolic blood pressure (SBP) relative to pre-EA control.
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f9: Action of electroacupuncture over a 6-month period assessed during monthly reinforcement therapy in a subgroup of 7 hypertensive patients. After 8 weeks of weekly EA, continued monthly EA treatment maintained a low systolic blood pressure (SBP) relative to pre-EA control.

Mentions: The effectiveness of EA persisted in a small group of 7 high responders during a 6-month period when reinforcement therapy was applied once monthly after an initial period of 8 weeks of weekly acupuncture (Fig. 9). Average SBP was reduced by 13 mmHg after 8 weeks of treatment and decreased by 16 mmHg, compared with pretreatment levels, after 6 months of reinforcement EA. Compared with pretreatment values, peak SBP was reduced by 16 mmHg after 8 weeks of treatment and 25 mmHg after 6 months of therapy.


Long-Lasting Reduction of Blood Pressure by Electroacupuncture in Patients with Hypertension: Randomized Controlled Trial.

Li P, Tjen-A-Looi SC, Cheng L, Liu D, Painovich J, Vinjamury S, Longhurst JC - Med Acupunct (2015)

Action of electroacupuncture over a 6-month period assessed during monthly reinforcement therapy in a subgroup of 7 hypertensive patients. After 8 weeks of weekly EA, continued monthly EA treatment maintained a low systolic blood pressure (SBP) relative to pre-EA control.
© Copyright Policy - open-access
Related In: Results  -  Collection

License
Show All Figures
getmorefigures.php?uid=PMC4555646&req=5

f9: Action of electroacupuncture over a 6-month period assessed during monthly reinforcement therapy in a subgroup of 7 hypertensive patients. After 8 weeks of weekly EA, continued monthly EA treatment maintained a low systolic blood pressure (SBP) relative to pre-EA control.
Mentions: The effectiveness of EA persisted in a small group of 7 high responders during a 6-month period when reinforcement therapy was applied once monthly after an initial period of 8 weeks of weekly acupuncture (Fig. 9). Average SBP was reduced by 13 mmHg after 8 weeks of treatment and decreased by 16 mmHg, compared with pretreatment levels, after 6 months of reinforcement EA. Compared with pretreatment values, peak SBP was reduced by 16 mmHg after 8 weeks of treatment and 25 mmHg after 6 months of therapy.

Bottom Line: Objective: To examine effectiveness of electroacupuncture (EA) at select acupoints to reduce systolic blood pressure (SBP) and diastolic blood pressures (DBP) in hypertensive patients.Results: After 8 weeks, 33 patients treated with EA at PC 5-6+ST 36-37 had decreased peak and average SBP and DBP, compared with 32 patients treated with EA at LI 6-7+GB 37-39 control acupoints.Conclusions: EA at select acupoints reduces blood pressure.

View Article: PubMed Central - PubMed

Affiliation: Susan-Samueli Center for Integrative Medicine, University of California , Irvine, School of Medicine, Irvine, CA.

ABSTRACT

Background: Acupuncture at specific acupoints has experimentally been found to reduce chronically elevated blood pressure. Objective: To examine effectiveness of electroacupuncture (EA) at select acupoints to reduce systolic blood pressure (SBP) and diastolic blood pressures (DBP) in hypertensive patients. Design: Two-arm parallel study. Patients: Sixty-five hypertensive patients not receiving medication were assigned randomly to one of the two acupuncture intervention (33 versus 32 patients). Intervention: Patients were assessed with 24-hour ambulatory blood pressure monitoring. They were treated with 30-minutes of EA at PC 5-6+ST 36-37 or LI 6-7+GB 37-39 once weekly for 8 weeks. Four acupuncturists provided single-blinded treatment. Main outcome measures: Primary outcomes measuring effectiveness of EA were peak and average SBP and DBP. Secondary outcomes examined underlying mechanisms of acupuncture with plasma norepinephrine, renin, and aldosterone before and after 8 weeks of treatment. Outcomes were obtained by double-blinded evaluation. Results: After 8 weeks, 33 patients treated with EA at PC 5-6+ST 36-37 had decreased peak and average SBP and DBP, compared with 32 patients treated with EA at LI 6-7+GB 37-39 control acupoints. Changes in blood pressures significantly differed between the two patient groups. In 14 patients, a long-lasting blood pressure-lowering acupuncture effect was observed for an additional 4 weeks of EA at PC 5-6+ST 36-37. After treatment, the plasma concentration of norepinephrine, which was initially elevated, was decreased by 41%; likewise, renin was decreased by 67% and aldosterone by 22%. Conclusions: EA at select acupoints reduces blood pressure. Sympathetic and renin-aldosterone systems were likely related to the long-lasting EA actions.

No MeSH data available.