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Correlation Analysis of Potential Factors Influencing Graft Maturity After Anterior Cruciate Ligament Reconstruction.

Li H, Chen S, Tao H, Li H, Chen S - Orthop J Sports Med (2014)

Bottom Line: There was a significant association between graft SNQ and postoperative time (r = -0.431, P < .001), TAS (r = 0.295, P = .002), and ACL-Blumensaat line angle (r = -0.304, P = .002).The graft SNQ value had a significant positive correlation with physical activity level and a significant negative correlation with postoperative time in this study.Males with a shorter postoperative time and a higher physical activity level had higher graft signal intensity postoperatively.

View Article: PubMed Central - PubMed

Affiliation: Department of Sports Medicine, Huashan Hospital, Shanghai, People's Republic of China.

ABSTRACT

Background: Postoperatively, signal changes of the reconstructed anterior cruciate ligament (ACL) graft on magnetic resonance imaging (MRI) images commonly occurs, which may be a cause for concern. The signal intensity changes are usually expressed by signal/noise quotient (SNQ) value, representing graft maturity. To date, little is known about the factors influencing the SNQ value of the reconstructed ACL graft.

Purpose: To evaluate ACL graft SNQ value and associated factors after ACL reconstruction.

Study design: Case series; Level of evidence, 4.

Methods: Male patients who underwent ACL reconstruction using autograft or allograft tendon from September 2004 to September 2011 were randomly invited to take part in this investigation, including functional scores, physical examination, and MRI scan. The femoral side graft was fixed with Endobutton CL or Rigidfix pins, and the tibial side graft was fixed with a bio-intrafix. SNQ values of each graft were measured on MRI to represent graft maturity. Sagittal ACL angle, ACL-Blumensaat line angle, and medial and lateral posterior tibial slope (PTS) were measured using MRI 3-dimensional dual-echo steady-state images. Potential risk factors, including age, body mass index, postoperative time, Tegner activity scale (TAS), sagittal ACL angle, ACL-Blumensaat line angle, medial PTS, lateral PTS, and primary graft diameter, were tested for their association with the graft SNQ value by multivariate stepwise regression analysis.

Results: A total of 104 male subjects (mean follow-up, 30.7 months) were examined, including 62 allograft and 42 autograft reconstructions. There was a significant association between graft SNQ and postoperative time (r = -0.431, P < .001), TAS (r = 0.295, P = .002), and ACL-Blumensaat line angle (r = -0.304, P = .002). Univariate regression analysis showed that TAS (β = 6.15, P < .001) positively correlated, postoperative time (β = -0.26, P < .001) negatively correlated, and ACL-Blumensaat line angle (β = -0.40, P = .038) negatively correlated with graft SNQ. Multivariate stepwise regression analysis showed that TAS, postoperative time, ACL-Blumensaat line angle, and age were significant independent factors associated with graft SNQ.

Conclusion: The graft SNQ value had a significant positive correlation with physical activity level and a significant negative correlation with postoperative time in this study. Males with a shorter postoperative time and a higher physical activity level had higher graft signal intensity postoperatively.

No MeSH data available.


Related in: MedlinePlus

Correlation between postoperative time and the mean signal/noise quotient (SNQ) value. There was a significant negative association between the postoperative time and graft SNQ value in the total group and the allograft group.
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fig2-2325967114553552: Correlation between postoperative time and the mean signal/noise quotient (SNQ) value. There was a significant negative association between the postoperative time and graft SNQ value in the total group and the allograft group.

Mentions: The ICC index of intraobserver reliabilities was 0.85 for the SNQ value of the graft. Possible associations between potential risk factors and SNQ value of the graft were explored. There was no significant association between graft SNQ value and age, BMI, sagittal ACL angle, medial PTS, lateral PTS, or primary graft diameter. Graft SNQ had a significant association with postoperative time (r = −0.431, P < .001), TAS (r = 0.295, P = .002), and ACL–Blumensaat line angle (r = −0.304, P = .002). The graft SNQ of the allograft tendon group was significantly higher than that of the autograft tendon group (14.4 ± 13.8 vs 9.2 ± 9.9, respectively; P = .038). For the allograft, graft SNQ had a significant association with postoperative time (r = −0.467, P < .001) and TAS (r = 0.385, P < .001). For the autograft, graft SNQ had a significant association with TAS (r = 0.392, P = .01) and ACL–Blumensaat line angle (r = −0.322, P = .038). Scatter plots of the graft SNQ according to the postoperative time, the TAS, and the ACL–Blumensaat line angle are shown in Figures 2 to 4.


Correlation Analysis of Potential Factors Influencing Graft Maturity After Anterior Cruciate Ligament Reconstruction.

Li H, Chen S, Tao H, Li H, Chen S - Orthop J Sports Med (2014)

Correlation between postoperative time and the mean signal/noise quotient (SNQ) value. There was a significant negative association between the postoperative time and graft SNQ value in the total group and the allograft group.
© Copyright Policy - creative-commons
Related In: Results  -  Collection

License 1 - License 2 - License 3
Show All Figures
getmorefigures.php?uid=PMC4555546&req=5

fig2-2325967114553552: Correlation between postoperative time and the mean signal/noise quotient (SNQ) value. There was a significant negative association between the postoperative time and graft SNQ value in the total group and the allograft group.
Mentions: The ICC index of intraobserver reliabilities was 0.85 for the SNQ value of the graft. Possible associations between potential risk factors and SNQ value of the graft were explored. There was no significant association between graft SNQ value and age, BMI, sagittal ACL angle, medial PTS, lateral PTS, or primary graft diameter. Graft SNQ had a significant association with postoperative time (r = −0.431, P < .001), TAS (r = 0.295, P = .002), and ACL–Blumensaat line angle (r = −0.304, P = .002). The graft SNQ of the allograft tendon group was significantly higher than that of the autograft tendon group (14.4 ± 13.8 vs 9.2 ± 9.9, respectively; P = .038). For the allograft, graft SNQ had a significant association with postoperative time (r = −0.467, P < .001) and TAS (r = 0.385, P < .001). For the autograft, graft SNQ had a significant association with TAS (r = 0.392, P = .01) and ACL–Blumensaat line angle (r = −0.322, P = .038). Scatter plots of the graft SNQ according to the postoperative time, the TAS, and the ACL–Blumensaat line angle are shown in Figures 2 to 4.

Bottom Line: There was a significant association between graft SNQ and postoperative time (r = -0.431, P < .001), TAS (r = 0.295, P = .002), and ACL-Blumensaat line angle (r = -0.304, P = .002).The graft SNQ value had a significant positive correlation with physical activity level and a significant negative correlation with postoperative time in this study.Males with a shorter postoperative time and a higher physical activity level had higher graft signal intensity postoperatively.

View Article: PubMed Central - PubMed

Affiliation: Department of Sports Medicine, Huashan Hospital, Shanghai, People's Republic of China.

ABSTRACT

Background: Postoperatively, signal changes of the reconstructed anterior cruciate ligament (ACL) graft on magnetic resonance imaging (MRI) images commonly occurs, which may be a cause for concern. The signal intensity changes are usually expressed by signal/noise quotient (SNQ) value, representing graft maturity. To date, little is known about the factors influencing the SNQ value of the reconstructed ACL graft.

Purpose: To evaluate ACL graft SNQ value and associated factors after ACL reconstruction.

Study design: Case series; Level of evidence, 4.

Methods: Male patients who underwent ACL reconstruction using autograft or allograft tendon from September 2004 to September 2011 were randomly invited to take part in this investigation, including functional scores, physical examination, and MRI scan. The femoral side graft was fixed with Endobutton CL or Rigidfix pins, and the tibial side graft was fixed with a bio-intrafix. SNQ values of each graft were measured on MRI to represent graft maturity. Sagittal ACL angle, ACL-Blumensaat line angle, and medial and lateral posterior tibial slope (PTS) were measured using MRI 3-dimensional dual-echo steady-state images. Potential risk factors, including age, body mass index, postoperative time, Tegner activity scale (TAS), sagittal ACL angle, ACL-Blumensaat line angle, medial PTS, lateral PTS, and primary graft diameter, were tested for their association with the graft SNQ value by multivariate stepwise regression analysis.

Results: A total of 104 male subjects (mean follow-up, 30.7 months) were examined, including 62 allograft and 42 autograft reconstructions. There was a significant association between graft SNQ and postoperative time (r = -0.431, P < .001), TAS (r = 0.295, P = .002), and ACL-Blumensaat line angle (r = -0.304, P = .002). Univariate regression analysis showed that TAS (β = 6.15, P < .001) positively correlated, postoperative time (β = -0.26, P < .001) negatively correlated, and ACL-Blumensaat line angle (β = -0.40, P = .038) negatively correlated with graft SNQ. Multivariate stepwise regression analysis showed that TAS, postoperative time, ACL-Blumensaat line angle, and age were significant independent factors associated with graft SNQ.

Conclusion: The graft SNQ value had a significant positive correlation with physical activity level and a significant negative correlation with postoperative time in this study. Males with a shorter postoperative time and a higher physical activity level had higher graft signal intensity postoperatively.

No MeSH data available.


Related in: MedlinePlus