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The Content of the 14 Metals in Cancellous and Cortical Bone of the Hip Joint Affected by Osteoarthritis.

Zioła-Frankowska A, Kubaszewski Ł, Dąbrowski M, Kowalski A, Rogala P, Strzyżewski W, Łabędź W, Uklejewski R, Novotny K, Kanicky V, Frankowski M - Biomed Res Int (2015)

Bottom Line: The factors influencing Pb accumulation in bone tissue were tobacco, alcohol, gender, and age.In primary and secondary osteoarthritis of the hip, the content and interactions of elements are different (mainly those of Fe and Pb).There were no significant differences in the concentrations of elements in the femoral head and neck that could be attributed to residence or physical activity.

View Article: PubMed Central - PubMed

Affiliation: Department of Analytical Chemistry, Faculty of Chemistry, Adam Mickiewicz University in Poznań, 61-614 Poznań, Poland.

ABSTRACT
The aim of the study was to determine the content of particular elements Ca, Mg, P, Na, K, Zn, Cu, Fe, Mo, Cr, Ni, Ba, Sr, and Pb in the proximal femur bone tissue (cancellous and cortical bone) of 96 patients undergoing total hip replacement for osteoarthritis using ICP-AES and FAAS analytical techniques. The interdependencies among these elements and their correlations depended on factors including age, gender, place of residence, tobacco consumption, alcohol consumption, exposure to environmental pollution, physical activity, and type of degenerative change which were examined by statistical and chemometric methods. The factors that exerted the greatest influence on the elements in the femoral head and neck were tobacco smoking (higher Cr and Ni content in smokers), alcohol consumption (higher concentrations of Ni, Cu in people who consume alcohol), and gender (higher Cu, Zn, and Ni concentrations in men). The factors influencing Pb accumulation in bone tissue were tobacco, alcohol, gender, and age. In primary and secondary osteoarthritis of the hip, the content and interactions of elements are different (mainly those of Fe and Pb). There were no significant differences in the concentrations of elements in the femoral head and neck that could be attributed to residence or physical activity.

No MeSH data available.


Related in: MedlinePlus

A graphic illustration of Principal Components Analysis of contents of elements according to cigarette smoking for femoral neck. Projection of the variables on the factor plane of the first two principal components for smokers and nonsmokers.
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fig4: A graphic illustration of Principal Components Analysis of contents of elements according to cigarette smoking for femoral neck. Projection of the variables on the factor plane of the first two principal components for smokers and nonsmokers.

Mentions: The changes in the femoral neck between smoking and nonsmoking people are described by 6 important components, the total variance of which is 79.1% (Figure 4). The first component indicates, as above, the presence of structural elements Ca, P, Na, Mg and Zn in the structure of hydroxyapatite. The meaning of Mo, Cr, Cu and Ni in ion exchange is characterized by the second component, and in nonsmokers also Pb. The Pb, Sr, and K in smokers and the Cu, Ni, and Fe in nonsmokers are represented by the third component.


The Content of the 14 Metals in Cancellous and Cortical Bone of the Hip Joint Affected by Osteoarthritis.

Zioła-Frankowska A, Kubaszewski Ł, Dąbrowski M, Kowalski A, Rogala P, Strzyżewski W, Łabędź W, Uklejewski R, Novotny K, Kanicky V, Frankowski M - Biomed Res Int (2015)

A graphic illustration of Principal Components Analysis of contents of elements according to cigarette smoking for femoral neck. Projection of the variables on the factor plane of the first two principal components for smokers and nonsmokers.
© Copyright Policy
Related In: Results  -  Collection

License
Show All Figures
getmorefigures.php?uid=PMC4555358&req=5

fig4: A graphic illustration of Principal Components Analysis of contents of elements according to cigarette smoking for femoral neck. Projection of the variables on the factor plane of the first two principal components for smokers and nonsmokers.
Mentions: The changes in the femoral neck between smoking and nonsmoking people are described by 6 important components, the total variance of which is 79.1% (Figure 4). The first component indicates, as above, the presence of structural elements Ca, P, Na, Mg and Zn in the structure of hydroxyapatite. The meaning of Mo, Cr, Cu and Ni in ion exchange is characterized by the second component, and in nonsmokers also Pb. The Pb, Sr, and K in smokers and the Cu, Ni, and Fe in nonsmokers are represented by the third component.

Bottom Line: The factors influencing Pb accumulation in bone tissue were tobacco, alcohol, gender, and age.In primary and secondary osteoarthritis of the hip, the content and interactions of elements are different (mainly those of Fe and Pb).There were no significant differences in the concentrations of elements in the femoral head and neck that could be attributed to residence or physical activity.

View Article: PubMed Central - PubMed

Affiliation: Department of Analytical Chemistry, Faculty of Chemistry, Adam Mickiewicz University in Poznań, 61-614 Poznań, Poland.

ABSTRACT
The aim of the study was to determine the content of particular elements Ca, Mg, P, Na, K, Zn, Cu, Fe, Mo, Cr, Ni, Ba, Sr, and Pb in the proximal femur bone tissue (cancellous and cortical bone) of 96 patients undergoing total hip replacement for osteoarthritis using ICP-AES and FAAS analytical techniques. The interdependencies among these elements and their correlations depended on factors including age, gender, place of residence, tobacco consumption, alcohol consumption, exposure to environmental pollution, physical activity, and type of degenerative change which were examined by statistical and chemometric methods. The factors that exerted the greatest influence on the elements in the femoral head and neck were tobacco smoking (higher Cr and Ni content in smokers), alcohol consumption (higher concentrations of Ni, Cu in people who consume alcohol), and gender (higher Cu, Zn, and Ni concentrations in men). The factors influencing Pb accumulation in bone tissue were tobacco, alcohol, gender, and age. In primary and secondary osteoarthritis of the hip, the content and interactions of elements are different (mainly those of Fe and Pb). There were no significant differences in the concentrations of elements in the femoral head and neck that could be attributed to residence or physical activity.

No MeSH data available.


Related in: MedlinePlus