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Transcriptomic Analysis of Musca domestica to Reveal Key Genes of the Prophenoloxidase-Activating System.

Li D, Liang Y, Wang X, Wang L, Qi M, Yu Y, Luan Y - G3 (Bethesda) (2015)

Bottom Line: Of the 89,842 unigenes, based on a similarity search with known genes in other insects, 24 putative genes related to the proPO system were identified.Eight of the identified genes encoded for peptidoglycan recognition receptors, two encoded for prophenoloxidases, three encoded for prophenoloxidase-activating enzymes, and 11 encoded for serine proteinase inhibitors.Collectively, this study has provided the comprehensive transcriptomic data of an insect and some fundamental basis toward achieving understanding of the activation mechanisms and immune functions of the proPO system in M. domestica.

View Article: PubMed Central - PubMed

Affiliation: Biotechnology Department, The School of Biological Sciences and Biotechnology, University of Jinan, Jinan 250022, People's Republic of China chm_lidx@ujn.edu.cn.

No MeSH data available.


Related in: MedlinePlus

GO classification of predicted genes. Three GO categories of genes including biological process, cellular component, and molecular function were presented. The numbers of genes in a given functional group are shown to the right of the y-axis and the percentages are marked to the left of the y-axis.
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fig4: GO classification of predicted genes. Three GO categories of genes including biological process, cellular component, and molecular function were presented. The numbers of genes in a given functional group are shown to the right of the y-axis and the percentages are marked to the left of the y-axis.

Mentions: Of the 60,353 Nr hits, GO terms were assigned to 44,346 unigenes (49.4% of total) for functional categorization, which were divided into 59 functional groups, and were allocated into three main categories, including biological process, cellular component, and molecular function (Figure 4). The top five belonged to the groups of cellular process (32,548; 73.40%), single-organism process (28,495; 64.26%), cell and cell part (26,014; 58.66%), binding (24,663; 55.61%), and metabolic process (24,372; 54.96%). Seven groups including nucleoid, virion, virion part, channel regulator activity, metallochaperone activity, morphogen activity, and nutrient reservoir activity had more than 10 but less than 100 genes. No more than 10 genes were clustered to the groups of protein tag, cell killing, and receptor regulator activity.


Transcriptomic Analysis of Musca domestica to Reveal Key Genes of the Prophenoloxidase-Activating System.

Li D, Liang Y, Wang X, Wang L, Qi M, Yu Y, Luan Y - G3 (Bethesda) (2015)

GO classification of predicted genes. Three GO categories of genes including biological process, cellular component, and molecular function were presented. The numbers of genes in a given functional group are shown to the right of the y-axis and the percentages are marked to the left of the y-axis.
© Copyright Policy - open-access
Related In: Results  -  Collection

License
Show All Figures
getmorefigures.php?uid=PMC4555219&req=5

fig4: GO classification of predicted genes. Three GO categories of genes including biological process, cellular component, and molecular function were presented. The numbers of genes in a given functional group are shown to the right of the y-axis and the percentages are marked to the left of the y-axis.
Mentions: Of the 60,353 Nr hits, GO terms were assigned to 44,346 unigenes (49.4% of total) for functional categorization, which were divided into 59 functional groups, and were allocated into three main categories, including biological process, cellular component, and molecular function (Figure 4). The top five belonged to the groups of cellular process (32,548; 73.40%), single-organism process (28,495; 64.26%), cell and cell part (26,014; 58.66%), binding (24,663; 55.61%), and metabolic process (24,372; 54.96%). Seven groups including nucleoid, virion, virion part, channel regulator activity, metallochaperone activity, morphogen activity, and nutrient reservoir activity had more than 10 but less than 100 genes. No more than 10 genes were clustered to the groups of protein tag, cell killing, and receptor regulator activity.

Bottom Line: Of the 89,842 unigenes, based on a similarity search with known genes in other insects, 24 putative genes related to the proPO system were identified.Eight of the identified genes encoded for peptidoglycan recognition receptors, two encoded for prophenoloxidases, three encoded for prophenoloxidase-activating enzymes, and 11 encoded for serine proteinase inhibitors.Collectively, this study has provided the comprehensive transcriptomic data of an insect and some fundamental basis toward achieving understanding of the activation mechanisms and immune functions of the proPO system in M. domestica.

View Article: PubMed Central - PubMed

Affiliation: Biotechnology Department, The School of Biological Sciences and Biotechnology, University of Jinan, Jinan 250022, People's Republic of China chm_lidx@ujn.edu.cn.

No MeSH data available.


Related in: MedlinePlus