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Technical advances in endoscopic ultrasound-guided fiducial placement for the treatment of pancreatic cancer.

Chavalitdhamrong D, DiMaio CJ, Siersema PD, Wagh MS - Endosc Int Open (2015)

Bottom Line: Because of the challenge of delivering an accurate and optimal radiation dose, image-guided radiation therapy can be used to improve targeting.Fiducial markers can be placed in the tumor and used for localization in patients undergoing image-guided radiation therapy.We herein review the technique, efficacy, and safety profile of EUS-guided fiducial placement.

View Article: PubMed Central - PubMed

Affiliation: Division of Gastroenterology, University of Florida, Gainesville, Florida, United States.

ABSTRACT
Radiation therapy has an important role in the treatment of locally advanced or metastatic pancreatic cancer and can be used alone or in conjunction with surgery and/or systemic chemotherapy. Because of the challenge of delivering an accurate and optimal radiation dose, image-guided radiation therapy can be used to improve targeting. Fiducial markers can be placed in the tumor and used for localization in patients undergoing image-guided radiation therapy. The safety and feasibility of endoscopic ultrasound (EUS)-guided placement of fiducials has been assessed and reported for the management of pancreatic cancer. We herein review the technique, efficacy, and safety profile of EUS-guided fiducial placement. In addition, we highlight recent advances and technological upgrades in EUS-guided fiducial delivery systems for pancreatic cancer most relevant to practicing gastroenterologists and interventional endoscopists.

No MeSH data available.


Related in: MedlinePlus

 The BNX needle aspiration system.
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FI197-4:  The BNX needle aspiration system.

Mentions: Recently, the BNX needle aspiration system (Covidien, Dublin, Ireland) has been introduced for EUS fine-needle aspiration and EUS-guided fiducial placement (Fig. 4) 24. It is engineered to improve clinical workflow by facilitating the passage of multiple needles through a single delivery system without removing the delivery system between needle passages. It allows rapid exchange of the needles while keeping the needle sheath and catheter in the echoendoscope. Therefore, having two or three preloaded needles can allow rapid deployment of multiple fiducials (this system allows placement of multiple fiducials through a single delivery system).


Technical advances in endoscopic ultrasound-guided fiducial placement for the treatment of pancreatic cancer.

Chavalitdhamrong D, DiMaio CJ, Siersema PD, Wagh MS - Endosc Int Open (2015)

 The BNX needle aspiration system.
© Copyright Policy
Related In: Results  -  Collection

Show All Figures
getmorefigures.php?uid=PMC4554510&req=5

FI197-4:  The BNX needle aspiration system.
Mentions: Recently, the BNX needle aspiration system (Covidien, Dublin, Ireland) has been introduced for EUS fine-needle aspiration and EUS-guided fiducial placement (Fig. 4) 24. It is engineered to improve clinical workflow by facilitating the passage of multiple needles through a single delivery system without removing the delivery system between needle passages. It allows rapid exchange of the needles while keeping the needle sheath and catheter in the echoendoscope. Therefore, having two or three preloaded needles can allow rapid deployment of multiple fiducials (this system allows placement of multiple fiducials through a single delivery system).

Bottom Line: Because of the challenge of delivering an accurate and optimal radiation dose, image-guided radiation therapy can be used to improve targeting.Fiducial markers can be placed in the tumor and used for localization in patients undergoing image-guided radiation therapy.We herein review the technique, efficacy, and safety profile of EUS-guided fiducial placement.

View Article: PubMed Central - PubMed

Affiliation: Division of Gastroenterology, University of Florida, Gainesville, Florida, United States.

ABSTRACT
Radiation therapy has an important role in the treatment of locally advanced or metastatic pancreatic cancer and can be used alone or in conjunction with surgery and/or systemic chemotherapy. Because of the challenge of delivering an accurate and optimal radiation dose, image-guided radiation therapy can be used to improve targeting. Fiducial markers can be placed in the tumor and used for localization in patients undergoing image-guided radiation therapy. The safety and feasibility of endoscopic ultrasound (EUS)-guided placement of fiducials has been assessed and reported for the management of pancreatic cancer. We herein review the technique, efficacy, and safety profile of EUS-guided fiducial placement. In addition, we highlight recent advances and technological upgrades in EUS-guided fiducial delivery systems for pancreatic cancer most relevant to practicing gastroenterologists and interventional endoscopists.

No MeSH data available.


Related in: MedlinePlus