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Graphene oxide-modified ZnO particles: synthesis, characterization, and antibacterial properties.

Zhong L, Yun K - Int J Nanomedicine (2015)

Bottom Line: The morphology of the graphene oxide sheets and ZnO particles was confirmed with field emission scanning electron microscopy and biological atomic force microscopy.Enhanced electrochemical properties were detected with cyclic voltammetry, with a redox peak of the composites at 0.025 mV.After further study of the antibacterial mechanism, we concluded that a vast number of reactive oxygen species formed on the surface of composites, improving antibacterial properties.

View Article: PubMed Central - PubMed

Affiliation: Department of Bionanotechnology, Gachon University, Gyeonggi-do, Republic of Korea.

ABSTRACT
Nanosized ZnO particles with diameters of 15 nm were prepared with a solution precipitation method at low cost and high yield. The synthesis of the particles was functionalized by the organic solvent dimethylformamide, and the particles were covalently bonded to the surface of graphene oxide. The morphology of the graphene oxide sheets and ZnO particles was confirmed with field emission scanning electron microscopy and biological atomic force microscopy. Fourier transform infrared spectroscopy and X-ray diffraction were used to analyze the physical and chemical properties of the ZnO/graphene oxide composites that differed from those of the individual components. Enhanced electrochemical properties were detected with cyclic voltammetry, with a redox peak of the composites at 0.025 mV. Excellent antibacterial activity of ZnO/graphene oxide composites was observed with a microdilution method in which minimum inhibitory concentrations of 6.25 µg/mL for Escherichia coli and Salmonella typhimurium, 12.5 µg/mL for Bacillus subtilis, and 25 µg/mL for Enterococcus faecalis. After further study of the antibacterial mechanism, we concluded that a vast number of reactive oxygen species formed on the surface of composites, improving antibacterial properties.

No MeSH data available.


Related in: MedlinePlus

CV curves.Notes: (A) Bare Au-PCB; (B) Au-PCB/graphene oxide; (C) Au-PCB/ZnO/graphene oxide hybrids.Abbreviations: CV, cyclic voltammetry; Au-PCB, gold printed circuit board; ZnO, zinc oxide.
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f8-ijn-10-079: CV curves.Notes: (A) Bare Au-PCB; (B) Au-PCB/graphene oxide; (C) Au-PCB/ZnO/graphene oxide hybrids.Abbreviations: CV, cyclic voltammetry; Au-PCB, gold printed circuit board; ZnO, zinc oxide.

Mentions: Electrochemical experiments were carried out with a three-electrode cell comprising an Au-PCB working electrode, Pt wire auxiliary electrode, and Ag/AgCl reference electrode. Figure 8A and B shows that no redox peaks appear on the bare Au-PCB and Au-PCB/graphene oxide within a potential range of −0.15 V to +0.25 V at a constant scan rate of 40 mV/s. However, the Au-PCB/ZnO/graphene oxide composites show apparent redox peaks at 0.025 V. We attributed this change to the combination of ZnO particles with graphene oxide via covalent bonds and to robust electron transfer at the redox center of graphene oxide.


Graphene oxide-modified ZnO particles: synthesis, characterization, and antibacterial properties.

Zhong L, Yun K - Int J Nanomedicine (2015)

CV curves.Notes: (A) Bare Au-PCB; (B) Au-PCB/graphene oxide; (C) Au-PCB/ZnO/graphene oxide hybrids.Abbreviations: CV, cyclic voltammetry; Au-PCB, gold printed circuit board; ZnO, zinc oxide.
© Copyright Policy
Related In: Results  -  Collection

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Show All Figures
getmorefigures.php?uid=PMC4554433&req=5

f8-ijn-10-079: CV curves.Notes: (A) Bare Au-PCB; (B) Au-PCB/graphene oxide; (C) Au-PCB/ZnO/graphene oxide hybrids.Abbreviations: CV, cyclic voltammetry; Au-PCB, gold printed circuit board; ZnO, zinc oxide.
Mentions: Electrochemical experiments were carried out with a three-electrode cell comprising an Au-PCB working electrode, Pt wire auxiliary electrode, and Ag/AgCl reference electrode. Figure 8A and B shows that no redox peaks appear on the bare Au-PCB and Au-PCB/graphene oxide within a potential range of −0.15 V to +0.25 V at a constant scan rate of 40 mV/s. However, the Au-PCB/ZnO/graphene oxide composites show apparent redox peaks at 0.025 V. We attributed this change to the combination of ZnO particles with graphene oxide via covalent bonds and to robust electron transfer at the redox center of graphene oxide.

Bottom Line: The morphology of the graphene oxide sheets and ZnO particles was confirmed with field emission scanning electron microscopy and biological atomic force microscopy.Enhanced electrochemical properties were detected with cyclic voltammetry, with a redox peak of the composites at 0.025 mV.After further study of the antibacterial mechanism, we concluded that a vast number of reactive oxygen species formed on the surface of composites, improving antibacterial properties.

View Article: PubMed Central - PubMed

Affiliation: Department of Bionanotechnology, Gachon University, Gyeonggi-do, Republic of Korea.

ABSTRACT
Nanosized ZnO particles with diameters of 15 nm were prepared with a solution precipitation method at low cost and high yield. The synthesis of the particles was functionalized by the organic solvent dimethylformamide, and the particles were covalently bonded to the surface of graphene oxide. The morphology of the graphene oxide sheets and ZnO particles was confirmed with field emission scanning electron microscopy and biological atomic force microscopy. Fourier transform infrared spectroscopy and X-ray diffraction were used to analyze the physical and chemical properties of the ZnO/graphene oxide composites that differed from those of the individual components. Enhanced electrochemical properties were detected with cyclic voltammetry, with a redox peak of the composites at 0.025 mV. Excellent antibacterial activity of ZnO/graphene oxide composites was observed with a microdilution method in which minimum inhibitory concentrations of 6.25 µg/mL for Escherichia coli and Salmonella typhimurium, 12.5 µg/mL for Bacillus subtilis, and 25 µg/mL for Enterococcus faecalis. After further study of the antibacterial mechanism, we concluded that a vast number of reactive oxygen species formed on the surface of composites, improving antibacterial properties.

No MeSH data available.


Related in: MedlinePlus