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Graphene oxide-modified ZnO particles: synthesis, characterization, and antibacterial properties.

Zhong L, Yun K - Int J Nanomedicine (2015)

Bottom Line: The morphology of the graphene oxide sheets and ZnO particles was confirmed with field emission scanning electron microscopy and biological atomic force microscopy.Enhanced electrochemical properties were detected with cyclic voltammetry, with a redox peak of the composites at 0.025 mV.After further study of the antibacterial mechanism, we concluded that a vast number of reactive oxygen species formed on the surface of composites, improving antibacterial properties.

View Article: PubMed Central - PubMed

Affiliation: Department of Bionanotechnology, Gachon University, Gyeonggi-do, Republic of Korea.

ABSTRACT
Nanosized ZnO particles with diameters of 15 nm were prepared with a solution precipitation method at low cost and high yield. The synthesis of the particles was functionalized by the organic solvent dimethylformamide, and the particles were covalently bonded to the surface of graphene oxide. The morphology of the graphene oxide sheets and ZnO particles was confirmed with field emission scanning electron microscopy and biological atomic force microscopy. Fourier transform infrared spectroscopy and X-ray diffraction were used to analyze the physical and chemical properties of the ZnO/graphene oxide composites that differed from those of the individual components. Enhanced electrochemical properties were detected with cyclic voltammetry, with a redox peak of the composites at 0.025 mV. Excellent antibacterial activity of ZnO/graphene oxide composites was observed with a microdilution method in which minimum inhibitory concentrations of 6.25 µg/mL for Escherichia coli and Salmonella typhimurium, 12.5 µg/mL for Bacillus subtilis, and 25 µg/mL for Enterococcus faecalis. After further study of the antibacterial mechanism, we concluded that a vast number of reactive oxygen species formed on the surface of composites, improving antibacterial properties.

No MeSH data available.


Related in: MedlinePlus

FT-IR spectrum.Notes: (A) the peak of graphene oxide at 1,000 cm−1, 1,150 cm−1, 1,650 cm−1, 1,750 cm−1, and 3,350 cm−1 represented C–O, C–OH, C=C, C=O, and O–H, respectively; (B) ZnO/graphene oxide composites at 650 cm−1, a special peak attributed to the Zn–O vibration.Abbreviations: FT-IR, Fourier transform infrared; ZnO, zinc oxide.
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f7-ijn-10-079: FT-IR spectrum.Notes: (A) the peak of graphene oxide at 1,000 cm−1, 1,150 cm−1, 1,650 cm−1, 1,750 cm−1, and 3,350 cm−1 represented C–O, C–OH, C=C, C=O, and O–H, respectively; (B) ZnO/graphene oxide composites at 650 cm−1, a special peak attributed to the Zn–O vibration.Abbreviations: FT-IR, Fourier transform infrared; ZnO, zinc oxide.

Mentions: The structure analysis of wurtzite ZnO was further supported with FT-IR spectroscopy. The FT-IR peaks of graphene oxide are shown in Figure 7A at 1,050 cm−1, 1,150 cm−1, 1,200 cm−1, 1,450 cm−1, and 3,260 cm−1.36 The peak at 1,000 cm−1 was attributed to C–O vibrations of the graphitic domains. The C–OH group exhibited its peak at 1,150 cm−1. The C=C groups and C=O groups came from carboxylic acid, and their peaks were observed at 1,650 cm−1 and 1,750 cm−1, respectively. The peak at 3,350 cm−1 was from the O–H groups due to water remaining in graphene oxide. Complete water removal is impossible because graphene oxide absorbs water from the air. Figure 7B shows that the ZnO/graphene oxide composites shared identical peaks with graphene oxide, but a new broad peak was observed at 650 cm−1 and was attributed to Zn–O vibrations. These vibrations indicate that ZnO particles were anchored to the graphene oxide sheets.


Graphene oxide-modified ZnO particles: synthesis, characterization, and antibacterial properties.

Zhong L, Yun K - Int J Nanomedicine (2015)

FT-IR spectrum.Notes: (A) the peak of graphene oxide at 1,000 cm−1, 1,150 cm−1, 1,650 cm−1, 1,750 cm−1, and 3,350 cm−1 represented C–O, C–OH, C=C, C=O, and O–H, respectively; (B) ZnO/graphene oxide composites at 650 cm−1, a special peak attributed to the Zn–O vibration.Abbreviations: FT-IR, Fourier transform infrared; ZnO, zinc oxide.
© Copyright Policy
Related In: Results  -  Collection

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getmorefigures.php?uid=PMC4554433&req=5

f7-ijn-10-079: FT-IR spectrum.Notes: (A) the peak of graphene oxide at 1,000 cm−1, 1,150 cm−1, 1,650 cm−1, 1,750 cm−1, and 3,350 cm−1 represented C–O, C–OH, C=C, C=O, and O–H, respectively; (B) ZnO/graphene oxide composites at 650 cm−1, a special peak attributed to the Zn–O vibration.Abbreviations: FT-IR, Fourier transform infrared; ZnO, zinc oxide.
Mentions: The structure analysis of wurtzite ZnO was further supported with FT-IR spectroscopy. The FT-IR peaks of graphene oxide are shown in Figure 7A at 1,050 cm−1, 1,150 cm−1, 1,200 cm−1, 1,450 cm−1, and 3,260 cm−1.36 The peak at 1,000 cm−1 was attributed to C–O vibrations of the graphitic domains. The C–OH group exhibited its peak at 1,150 cm−1. The C=C groups and C=O groups came from carboxylic acid, and their peaks were observed at 1,650 cm−1 and 1,750 cm−1, respectively. The peak at 3,350 cm−1 was from the O–H groups due to water remaining in graphene oxide. Complete water removal is impossible because graphene oxide absorbs water from the air. Figure 7B shows that the ZnO/graphene oxide composites shared identical peaks with graphene oxide, but a new broad peak was observed at 650 cm−1 and was attributed to Zn–O vibrations. These vibrations indicate that ZnO particles were anchored to the graphene oxide sheets.

Bottom Line: The morphology of the graphene oxide sheets and ZnO particles was confirmed with field emission scanning electron microscopy and biological atomic force microscopy.Enhanced electrochemical properties were detected with cyclic voltammetry, with a redox peak of the composites at 0.025 mV.After further study of the antibacterial mechanism, we concluded that a vast number of reactive oxygen species formed on the surface of composites, improving antibacterial properties.

View Article: PubMed Central - PubMed

Affiliation: Department of Bionanotechnology, Gachon University, Gyeonggi-do, Republic of Korea.

ABSTRACT
Nanosized ZnO particles with diameters of 15 nm were prepared with a solution precipitation method at low cost and high yield. The synthesis of the particles was functionalized by the organic solvent dimethylformamide, and the particles were covalently bonded to the surface of graphene oxide. The morphology of the graphene oxide sheets and ZnO particles was confirmed with field emission scanning electron microscopy and biological atomic force microscopy. Fourier transform infrared spectroscopy and X-ray diffraction were used to analyze the physical and chemical properties of the ZnO/graphene oxide composites that differed from those of the individual components. Enhanced electrochemical properties were detected with cyclic voltammetry, with a redox peak of the composites at 0.025 mV. Excellent antibacterial activity of ZnO/graphene oxide composites was observed with a microdilution method in which minimum inhibitory concentrations of 6.25 µg/mL for Escherichia coli and Salmonella typhimurium, 12.5 µg/mL for Bacillus subtilis, and 25 µg/mL for Enterococcus faecalis. After further study of the antibacterial mechanism, we concluded that a vast number of reactive oxygen species formed on the surface of composites, improving antibacterial properties.

No MeSH data available.


Related in: MedlinePlus