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Graphene oxide-modified ZnO particles: synthesis, characterization, and antibacterial properties.

Zhong L, Yun K - Int J Nanomedicine (2015)

Bottom Line: The morphology of the graphene oxide sheets and ZnO particles was confirmed with field emission scanning electron microscopy and biological atomic force microscopy.Enhanced electrochemical properties were detected with cyclic voltammetry, with a redox peak of the composites at 0.025 mV.After further study of the antibacterial mechanism, we concluded that a vast number of reactive oxygen species formed on the surface of composites, improving antibacterial properties.

View Article: PubMed Central - PubMed

Affiliation: Department of Bionanotechnology, Gachon University, Gyeonggi-do, Republic of Korea.

ABSTRACT
Nanosized ZnO particles with diameters of 15 nm were prepared with a solution precipitation method at low cost and high yield. The synthesis of the particles was functionalized by the organic solvent dimethylformamide, and the particles were covalently bonded to the surface of graphene oxide. The morphology of the graphene oxide sheets and ZnO particles was confirmed with field emission scanning electron microscopy and biological atomic force microscopy. Fourier transform infrared spectroscopy and X-ray diffraction were used to analyze the physical and chemical properties of the ZnO/graphene oxide composites that differed from those of the individual components. Enhanced electrochemical properties were detected with cyclic voltammetry, with a redox peak of the composites at 0.025 mV. Excellent antibacterial activity of ZnO/graphene oxide composites was observed with a microdilution method in which minimum inhibitory concentrations of 6.25 µg/mL for Escherichia coli and Salmonella typhimurium, 12.5 µg/mL for Bacillus subtilis, and 25 µg/mL for Enterococcus faecalis. After further study of the antibacterial mechanism, we concluded that a vast number of reactive oxygen species formed on the surface of composites, improving antibacterial properties.

No MeSH data available.


Related in: MedlinePlus

Illustration for the preparation of the Au-PCB/ZnO/graphene oxide platform.Abbreviations: Au-PCB, gold printed circuit board; ZnO, zinc oxide.
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f2-ijn-10-079: Illustration for the preparation of the Au-PCB/ZnO/graphene oxide platform.Abbreviations: Au-PCB, gold printed circuit board; ZnO, zinc oxide.

Mentions: The surface of the Au-PCB electrode was washed with anhydrous ethanol and deionized water for 3 minutes. Oxygen plasma treatment was then performed on the surface of the Au-PCB electrode for 120 seconds. The graphene oxide and composite liquid (5 µL) was dropped onto the surface of the Au-PCB electrode, and the electrode was left in ambient environment to dry. Finally, the immobilized PCB electrode was coated with 5 µL Nafion. The entire process is shown in Figure 2.


Graphene oxide-modified ZnO particles: synthesis, characterization, and antibacterial properties.

Zhong L, Yun K - Int J Nanomedicine (2015)

Illustration for the preparation of the Au-PCB/ZnO/graphene oxide platform.Abbreviations: Au-PCB, gold printed circuit board; ZnO, zinc oxide.
© Copyright Policy
Related In: Results  -  Collection

License
Show All Figures
getmorefigures.php?uid=PMC4554433&req=5

f2-ijn-10-079: Illustration for the preparation of the Au-PCB/ZnO/graphene oxide platform.Abbreviations: Au-PCB, gold printed circuit board; ZnO, zinc oxide.
Mentions: The surface of the Au-PCB electrode was washed with anhydrous ethanol and deionized water for 3 minutes. Oxygen plasma treatment was then performed on the surface of the Au-PCB electrode for 120 seconds. The graphene oxide and composite liquid (5 µL) was dropped onto the surface of the Au-PCB electrode, and the electrode was left in ambient environment to dry. Finally, the immobilized PCB electrode was coated with 5 µL Nafion. The entire process is shown in Figure 2.

Bottom Line: The morphology of the graphene oxide sheets and ZnO particles was confirmed with field emission scanning electron microscopy and biological atomic force microscopy.Enhanced electrochemical properties were detected with cyclic voltammetry, with a redox peak of the composites at 0.025 mV.After further study of the antibacterial mechanism, we concluded that a vast number of reactive oxygen species formed on the surface of composites, improving antibacterial properties.

View Article: PubMed Central - PubMed

Affiliation: Department of Bionanotechnology, Gachon University, Gyeonggi-do, Republic of Korea.

ABSTRACT
Nanosized ZnO particles with diameters of 15 nm were prepared with a solution precipitation method at low cost and high yield. The synthesis of the particles was functionalized by the organic solvent dimethylformamide, and the particles were covalently bonded to the surface of graphene oxide. The morphology of the graphene oxide sheets and ZnO particles was confirmed with field emission scanning electron microscopy and biological atomic force microscopy. Fourier transform infrared spectroscopy and X-ray diffraction were used to analyze the physical and chemical properties of the ZnO/graphene oxide composites that differed from those of the individual components. Enhanced electrochemical properties were detected with cyclic voltammetry, with a redox peak of the composites at 0.025 mV. Excellent antibacterial activity of ZnO/graphene oxide composites was observed with a microdilution method in which minimum inhibitory concentrations of 6.25 µg/mL for Escherichia coli and Salmonella typhimurium, 12.5 µg/mL for Bacillus subtilis, and 25 µg/mL for Enterococcus faecalis. After further study of the antibacterial mechanism, we concluded that a vast number of reactive oxygen species formed on the surface of composites, improving antibacterial properties.

No MeSH data available.


Related in: MedlinePlus