Limits...
Bone dynamics in the upward direction after a maxillary sinus floor elevation procedure: serial segmentation using synchrotron radiation micro-computed tomography.

Seo SJ, Bark CW, Lim JH, Kim YG - Int J Nanomedicine (2015)

Bottom Line: The bone dynamics between the new bone and bone substitutes along the inferior-superior direction in humans after maxillary sinus floor elevation (MSFE) were analyzed using the whole sample region.SR-μCT is highly effective for obtaining high-resolution images.An analysis of biological specimens using SR-μCT is quite reliable and this technique will be an important tool in the wide field of tissue engineering.

View Article: PubMed Central - PubMed

Affiliation: Industrial Technology Convergence Center, Pohang Accelerator Laboratory, POSTECH, Pohang, Gyeongbuk, Republic of Korea.

ABSTRACT

Objective: Maxillary sinus floor augmentation has been shown to be the most predictable surgical technique for enhancing the bone volume in the posterior area of the maxilla. The purpose of this study was to analyze the serial slice image segmentation of newly formed bone and bone substitutes after sinus floor elevation using synchrotron radiation X-ray micro-computed tomography (SR-μCT).

Materials and methods: Bone biopsy specimens were collected after 6 months of sinus floor augmentation. From the six bone biopsy specimens, the cross-sectional images at every 8 μm along the apical direction from the inferior border using serial segmentation from three-dimensional reconstructed X-ray images were analyzed. The amount of new bone and bone substitutes were measured at each slicing image (300-430 images per specimen).

Results: The bone dynamics between the new bone and bone substitutes along the inferior-superior direction in humans after maxillary sinus floor elevation (MSFE) were analyzed using the whole sample region. Although these observations suggest that the specimens are structurally inhomogeneous, sinus floor elevation was confirmed to be a reliable surgical procedure for increasing the amount of bone.

Conclusion: SR-μCT is highly effective for obtaining high-resolution images. An analysis of biological specimens using SR-μCT is quite reliable and this technique will be an important tool in the wide field of tissue engineering.

No MeSH data available.


Related in: MedlinePlus

The 3D visualization image of bone biopsy specimen acquired by SR-μCT.Notes: Whole bone specimen containing bone substitutes (Bio-Oss®), newly formed bone (red), bone substitutes (Bio-Oss®, pink). (A) Side view, (B) top view, and (C) cross section.Abbreviations: SR-μCT, synchrotron radiation X-ray micro-computed tomography; 3D, three-dimensional.
© Copyright Policy
Related In: Results  -  Collection

License
getmorefigures.php?uid=PMC4554393&req=5

f3-ijn-10-129: The 3D visualization image of bone biopsy specimen acquired by SR-μCT.Notes: Whole bone specimen containing bone substitutes (Bio-Oss®), newly formed bone (red), bone substitutes (Bio-Oss®, pink). (A) Side view, (B) top view, and (C) cross section.Abbreviations: SR-μCT, synchrotron radiation X-ray micro-computed tomography; 3D, three-dimensional.

Mentions: From the 3D image sets of SR-μCT, the cross sections that showed close similarity to the photomicrographs could be identified easily. Figure 3A and B shows a 3D visualization image of a bone biopsy specimen acquired by SR-μCT. This was a whole bone specimen containing NB and BSs (Bio-Oss®), newly formed bones were presented with red color, and BSs were present with pink color. The 3D visualization software that can make a cross-sectional view in the arbitrary direction is indispensable, as shown in Figure 3C.


Bone dynamics in the upward direction after a maxillary sinus floor elevation procedure: serial segmentation using synchrotron radiation micro-computed tomography.

Seo SJ, Bark CW, Lim JH, Kim YG - Int J Nanomedicine (2015)

The 3D visualization image of bone biopsy specimen acquired by SR-μCT.Notes: Whole bone specimen containing bone substitutes (Bio-Oss®), newly formed bone (red), bone substitutes (Bio-Oss®, pink). (A) Side view, (B) top view, and (C) cross section.Abbreviations: SR-μCT, synchrotron radiation X-ray micro-computed tomography; 3D, three-dimensional.
© Copyright Policy
Related In: Results  -  Collection

License
Show All Figures
getmorefigures.php?uid=PMC4554393&req=5

f3-ijn-10-129: The 3D visualization image of bone biopsy specimen acquired by SR-μCT.Notes: Whole bone specimen containing bone substitutes (Bio-Oss®), newly formed bone (red), bone substitutes (Bio-Oss®, pink). (A) Side view, (B) top view, and (C) cross section.Abbreviations: SR-μCT, synchrotron radiation X-ray micro-computed tomography; 3D, three-dimensional.
Mentions: From the 3D image sets of SR-μCT, the cross sections that showed close similarity to the photomicrographs could be identified easily. Figure 3A and B shows a 3D visualization image of a bone biopsy specimen acquired by SR-μCT. This was a whole bone specimen containing NB and BSs (Bio-Oss®), newly formed bones were presented with red color, and BSs were present with pink color. The 3D visualization software that can make a cross-sectional view in the arbitrary direction is indispensable, as shown in Figure 3C.

Bottom Line: The bone dynamics between the new bone and bone substitutes along the inferior-superior direction in humans after maxillary sinus floor elevation (MSFE) were analyzed using the whole sample region.SR-μCT is highly effective for obtaining high-resolution images.An analysis of biological specimens using SR-μCT is quite reliable and this technique will be an important tool in the wide field of tissue engineering.

View Article: PubMed Central - PubMed

Affiliation: Industrial Technology Convergence Center, Pohang Accelerator Laboratory, POSTECH, Pohang, Gyeongbuk, Republic of Korea.

ABSTRACT

Objective: Maxillary sinus floor augmentation has been shown to be the most predictable surgical technique for enhancing the bone volume in the posterior area of the maxilla. The purpose of this study was to analyze the serial slice image segmentation of newly formed bone and bone substitutes after sinus floor elevation using synchrotron radiation X-ray micro-computed tomography (SR-μCT).

Materials and methods: Bone biopsy specimens were collected after 6 months of sinus floor augmentation. From the six bone biopsy specimens, the cross-sectional images at every 8 μm along the apical direction from the inferior border using serial segmentation from three-dimensional reconstructed X-ray images were analyzed. The amount of new bone and bone substitutes were measured at each slicing image (300-430 images per specimen).

Results: The bone dynamics between the new bone and bone substitutes along the inferior-superior direction in humans after maxillary sinus floor elevation (MSFE) were analyzed using the whole sample region. Although these observations suggest that the specimens are structurally inhomogeneous, sinus floor elevation was confirmed to be a reliable surgical procedure for increasing the amount of bone.

Conclusion: SR-μCT is highly effective for obtaining high-resolution images. An analysis of biological specimens using SR-μCT is quite reliable and this technique will be an important tool in the wide field of tissue engineering.

No MeSH data available.


Related in: MedlinePlus