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Management of a One-wall Intrabony Osseous Defect with Combination of Platelet Rich Plasma and Demineralized Bone Matrix- a Two-year Follow up Case Report.

Thakkalapati P, R Chandran C, Ranganathan AT, Jain AR, Prabhakar P, Padmanaban S - J Dent (Shiraz) (2015)

Bottom Line: The 6-month follow- up results showed significant improvement in clinical parameters.Radiographic evidence of bone formation was observed as early as 3 months with almost complete fill by 6 months post-operatively.The results were maintained over a period of 2 years.

View Article: PubMed Central - PubMed

Affiliation: Dept. of Periodontics, Tagore Dental College and Hospitals, Chennai, India.

ABSTRACT
Periodontal regeneration in a one-wall intrabony defect is a challenging and complex phenomenon. The combination therapy of commercially available bone grafts with the innovative tissue engineering strategy, the platelet rich plasma, has emerged as a promising grafting modality for two and three walled intrabony osseous defects. The application of this combination approach was attempted in a most challenging one-wall intrabony defect. Open flap debridement and placement of combination of autologous platelet rich plasma(PRP) and demineralized bone matrix was done in one-wall intrabony defect in relation to tooth #21 in a 30 year old female patient. The 6-month follow- up results showed significant improvement in clinical parameters. Radiographic evidence of bone formation was observed as early as 3 months with almost complete fill by 6 months post-operatively. The results were maintained over a period of 2 years.

No MeSH data available.


a: Post-operative radiographic view of IOPA at 3rd month  b: Post-operative radiographic view of IOPA at 6th month
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Figure 5: a: Post-operative radiographic view of IOPA at 3rd month  b: Post-operative radiographic view of IOPA at 6th month

Mentions: At 6 months postoperatively in the region of tooth#21, clinical examination of the treated one wall intrabony defect showed significant probing depth reduction and clinical attachment gain compared to baseline values. The probing depth reduced to 0.5mm and gain in the clinical attachment levels was 6.5mm with no mobility or bleeding on probing. The radiographs also showed good bony fill which was almost complete by 6 months (Figure 5). The results were maintained up to the 2-year follow up period (Figure 6).


Management of a One-wall Intrabony Osseous Defect with Combination of Platelet Rich Plasma and Demineralized Bone Matrix- a Two-year Follow up Case Report.

Thakkalapati P, R Chandran C, Ranganathan AT, Jain AR, Prabhakar P, Padmanaban S - J Dent (Shiraz) (2015)

a: Post-operative radiographic view of IOPA at 3rd month  b: Post-operative radiographic view of IOPA at 6th month
© Copyright Policy
Related In: Results  -  Collection

License
Show All Figures
getmorefigures.php?uid=PMC4554316&req=5

Figure 5: a: Post-operative radiographic view of IOPA at 3rd month  b: Post-operative radiographic view of IOPA at 6th month
Mentions: At 6 months postoperatively in the region of tooth#21, clinical examination of the treated one wall intrabony defect showed significant probing depth reduction and clinical attachment gain compared to baseline values. The probing depth reduced to 0.5mm and gain in the clinical attachment levels was 6.5mm with no mobility or bleeding on probing. The radiographs also showed good bony fill which was almost complete by 6 months (Figure 5). The results were maintained up to the 2-year follow up period (Figure 6).

Bottom Line: The 6-month follow- up results showed significant improvement in clinical parameters.Radiographic evidence of bone formation was observed as early as 3 months with almost complete fill by 6 months post-operatively.The results were maintained over a period of 2 years.

View Article: PubMed Central - PubMed

Affiliation: Dept. of Periodontics, Tagore Dental College and Hospitals, Chennai, India.

ABSTRACT
Periodontal regeneration in a one-wall intrabony defect is a challenging and complex phenomenon. The combination therapy of commercially available bone grafts with the innovative tissue engineering strategy, the platelet rich plasma, has emerged as a promising grafting modality for two and three walled intrabony osseous defects. The application of this combination approach was attempted in a most challenging one-wall intrabony defect. Open flap debridement and placement of combination of autologous platelet rich plasma(PRP) and demineralized bone matrix was done in one-wall intrabony defect in relation to tooth #21 in a 30 year old female patient. The 6-month follow- up results showed significant improvement in clinical parameters. Radiographic evidence of bone formation was observed as early as 3 months with almost complete fill by 6 months post-operatively. The results were maintained over a period of 2 years.

No MeSH data available.