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Comparison of Antibacterial Effects of ZnO and CuO Nanoparticles Coated Brackets against Streptococcus Mutans.

Ramazanzadeh B, Jahanbin A, Yaghoubi M, Shahtahmassbi N, Ghazvini K, Shakeri M, Shafaee H - J Dent (Shiraz) (2015)

Bottom Line: The aim of this study was to compare the antibacterial effects of nano copper oxide (CuO) and nano zinc oxide (ZnO) coated brackets against Streptococcus mutans (S.mutans) in order to decrease the risk of caries around the orthodontic brackets during the treatment.During 6-24 hours, the growth of S.mutans was significantly reduced by ZnO nanoparticles in comparison with the control group (p< 0.001).CuO and ZnO-CuO nanoparticles coated brackets have better antimicrobial effect on S.mutans than ZnO coated brackets.

View Article: PubMed Central - PubMed

Affiliation: Dental Research Center, Dept. of Orthodontics, School of Dentistry, Mashhad University of Medical Sciences, Mashhad, Iran.

ABSTRACT

Statement of the problem: During the orthodontic treatment, microbial plaques may accumulate around the brackets and cause caries, especially in high-risk patients. Finding ways to eliminate this microbial plaque seems to be essential.

Purpose: The aim of this study was to compare the antibacterial effects of nano copper oxide (CuO) and nano zinc oxide (ZnO) coated brackets against Streptococcus mutans (S.mutans) in order to decrease the risk of caries around the orthodontic brackets during the treatment.

Materials and method: Sixty brackets were coated with nanoparticles of ZnO (n=20), CuO (n=20) and CuO-ZnO (n=20). Twelve uncoated brackets constituted the control group. The brackets were bonded to the crowns of extracted premolars, sterilized and prepared for antimicrobial tests (S.mutans ATCC35668). The samples taken after 0, 2, 4, 6 and 24 hours were cultured on agar plates. Colonies were counted 24 hours after incubation. One-way ANOVA and Tukey tests were used for statistical analysis.

Results: In CuO and CuO-ZnO coated brackets, no colony growth was seen after two hours. Between 0-6 hours, the mean colony counts were not significantly different between the ZnO and the control group (p>0.05). During 6-24 hours, the growth of S.mutans was significantly reduced by ZnO nanoparticles in comparison with the control group (p< 0.001). However, these bacteria were not totally eliminated.

Conclusion: CuO and ZnO-CuO nanoparticles coated brackets have better antimicrobial effect on S.mutans than ZnO coated brackets.

No MeSH data available.


Related in: MedlinePlus

Brackets color changes after coating with CuO-ZnO nanoparticles, CuO nanoparticles and ZnO nanoparticles in comparison with controls (left to right).
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Figure 3: Brackets color changes after coating with CuO-ZnO nanoparticles, CuO nanoparticles and ZnO nanoparticles in comparison with controls (left to right).

Mentions: In the CuO and ZnO-CuO groups, the color of the brackets changed to copper, which was cosmetically unsuitable (Figure 3).


Comparison of Antibacterial Effects of ZnO and CuO Nanoparticles Coated Brackets against Streptococcus Mutans.

Ramazanzadeh B, Jahanbin A, Yaghoubi M, Shahtahmassbi N, Ghazvini K, Shakeri M, Shafaee H - J Dent (Shiraz) (2015)

Brackets color changes after coating with CuO-ZnO nanoparticles, CuO nanoparticles and ZnO nanoparticles in comparison with controls (left to right).
© Copyright Policy
Related In: Results  -  Collection

License
Show All Figures
getmorefigures.php?uid=PMC4554313&req=5

Figure 3: Brackets color changes after coating with CuO-ZnO nanoparticles, CuO nanoparticles and ZnO nanoparticles in comparison with controls (left to right).
Mentions: In the CuO and ZnO-CuO groups, the color of the brackets changed to copper, which was cosmetically unsuitable (Figure 3).

Bottom Line: The aim of this study was to compare the antibacterial effects of nano copper oxide (CuO) and nano zinc oxide (ZnO) coated brackets against Streptococcus mutans (S.mutans) in order to decrease the risk of caries around the orthodontic brackets during the treatment.During 6-24 hours, the growth of S.mutans was significantly reduced by ZnO nanoparticles in comparison with the control group (p< 0.001).CuO and ZnO-CuO nanoparticles coated brackets have better antimicrobial effect on S.mutans than ZnO coated brackets.

View Article: PubMed Central - PubMed

Affiliation: Dental Research Center, Dept. of Orthodontics, School of Dentistry, Mashhad University of Medical Sciences, Mashhad, Iran.

ABSTRACT

Statement of the problem: During the orthodontic treatment, microbial plaques may accumulate around the brackets and cause caries, especially in high-risk patients. Finding ways to eliminate this microbial plaque seems to be essential.

Purpose: The aim of this study was to compare the antibacterial effects of nano copper oxide (CuO) and nano zinc oxide (ZnO) coated brackets against Streptococcus mutans (S.mutans) in order to decrease the risk of caries around the orthodontic brackets during the treatment.

Materials and method: Sixty brackets were coated with nanoparticles of ZnO (n=20), CuO (n=20) and CuO-ZnO (n=20). Twelve uncoated brackets constituted the control group. The brackets were bonded to the crowns of extracted premolars, sterilized and prepared for antimicrobial tests (S.mutans ATCC35668). The samples taken after 0, 2, 4, 6 and 24 hours were cultured on agar plates. Colonies were counted 24 hours after incubation. One-way ANOVA and Tukey tests were used for statistical analysis.

Results: In CuO and CuO-ZnO coated brackets, no colony growth was seen after two hours. Between 0-6 hours, the mean colony counts were not significantly different between the ZnO and the control group (p>0.05). During 6-24 hours, the growth of S.mutans was significantly reduced by ZnO nanoparticles in comparison with the control group (p< 0.001). However, these bacteria were not totally eliminated.

Conclusion: CuO and ZnO-CuO nanoparticles coated brackets have better antimicrobial effect on S.mutans than ZnO coated brackets.

No MeSH data available.


Related in: MedlinePlus