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Evaluation of microincision vitrectomy surgery using wide-viewing system for complications with ocular sarcoidosis.

Takayama K, Tanaka A, Shibata M, Muraoka T, Ishikawa S, Harimoto K, Takeuchi M - Medicine (Baltimore) (2015)

Bottom Line: The mean LogMAR was significantly improved from 1.14 ± 1.18 to 0.36 ± 0.79 in all eyes and 0.83 ± 0.86 to 0.23 ± 0.41 in eyes with MIVS and phacoemulsification, although no improvement was observed in eyes with MIVS only.Significant decrease of the mean anterior inflammation score was observed after 1 month in eyes with MIVS only and after 12 months in eyes with MIVS and phacoemulsification, and the mean posterior inflammation scores decreased after 1 week in all eyes.There was no case in which ocular inflammation was exacerbated by surgical stress.

View Article: PubMed Central - PubMed

Affiliation: From the Department of Ophthalmology, National Defense Medical College.

ABSTRACT
We evaluate the outcomes of microincision vitrectomy surgery (MIVS) using wide-viewing system for complications with ocular sarcoidosis resistance to medical treatment.Consecutive clinical records of 24 eyes (19 patients) with complications of ocular sarcoidosis underwent MIVS between April 2010 and December 2013 were retrospectively reviewed. MIVS and phacoemulsification were performed in 18 eyes and MIVS only in 6 eyes. Best-corrected visual acuity (BCVA), inflammation scores in the anterior segment and in the posterior segment, and central retinal thickness (CRT) of eyes with cystoid macular edema (CME) before surgery and after 1 week, 1, 3, 6, and 12 months were evaluated.LogMAR (log of the minimum angle of resolution) converted from BCVA was improved in 83.3% after 12 months and 66.7% showed improvement of more than 2 lines. The mean LogMAR was significantly improved from 1.14 ± 1.18 to 0.36 ± 0.79 in all eyes and 0.83 ± 0.86 to 0.23 ± 0.41 in eyes with MIVS and phacoemulsification, although no improvement was observed in eyes with MIVS only. Significant decrease of the mean anterior inflammation score was observed after 1 month in eyes with MIVS only and after 12 months in eyes with MIVS and phacoemulsification, and the mean posterior inflammation scores decreased after 1 week in all eyes. In eyes with preoperative CME, mean CRT was significantly decreased from 1 week after surgery. There was no case in which ocular inflammation was exacerbated by surgical stress. Improvement of visual acuity and resolution of ocular inflammation could be achieved by MIVS using wide-viewing system for complications of ocular sarcoidosis.

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Outcomes of visual acuity before and after MIVS. A: LogMAR converted from BCVA in individual eyes of sarcoidosis patients before surgery and at 12 months after surgery. B, C, and D: The mean LogMAR before surgery and at 1 week, 1, 3, 6, and 12 months after surgery in all eyes (B), eyes with MIVS only (C), and eyes with MIVS and phacoemulsification (D). ANOVA = analysis of variance, LogMAR = log of the minimum angle of resolution, MIVS = microincision vitrectomy surgery.
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Figure 1: Outcomes of visual acuity before and after MIVS. A: LogMAR converted from BCVA in individual eyes of sarcoidosis patients before surgery and at 12 months after surgery. B, C, and D: The mean LogMAR before surgery and at 1 week, 1, 3, 6, and 12 months after surgery in all eyes (B), eyes with MIVS only (C), and eyes with MIVS and phacoemulsification (D). ANOVA = analysis of variance, LogMAR = log of the minimum angle of resolution, MIVS = microincision vitrectomy surgery.

Mentions: The BCVA converted to LogMAR (log of the minimum angle of resolution) before surgery and after 1 week, 1, 3, 6, and 12 months is shown in Figure 1. Visual acuity was improved in 20 (83.3%) of 24 eyes after 12 months, 16 eyes (66.7%) showed improvement of more than 2 lines, whereas 4 eyes (16.7%) showed worsened or unchanged visual acuity (Figure 1A). The mean LogMAR in all eyes decreased from 1.14 ± 1.18 before surgery to 0.43 ± 0.55 at 1 week, 0.47 ± 0.74 at 1 month, 0.43 ± 0.73 at 3 months, 0.35 ± 0.67 at 6 months, and 0.36 ± 0.79 at 12 months after surgery, and significant improvements (P = .0028) were observed from 1 week (Figure 1B). When the cases were classified into MIVS only group and MIVS with phacoemulsification group, the mean LogMAR in MIVS only group was 1.26 ± 1.52 before surgery, and changed to 0.86 ± 0.92 at 1 week, 1.07 ± 1.35 after 1 month, 1.24 ± 1.51 at 3 months, 1.02 ± 1.72 at 6 months, and 1.03 ± 1.40 at 12 months (Table 2). There were no significant differences (P = .47) (Figure 1C). In MIVS with phacoemulsification group, the mean LogMAR was 1.05 ± 1.12 before surgery, changed to 0.34 ± 0.51 at 1 week, 0.26 ± 0.35 at 1 month, 0.23 ± 0.36 at 3 months, 0.21 ± 0.35 at 6 months, and 0.23 ± 0.41 at 12 months, and significantly decreased (P = .0027) after 1 week (Figure 1D).


Evaluation of microincision vitrectomy surgery using wide-viewing system for complications with ocular sarcoidosis.

Takayama K, Tanaka A, Shibata M, Muraoka T, Ishikawa S, Harimoto K, Takeuchi M - Medicine (Baltimore) (2015)

Outcomes of visual acuity before and after MIVS. A: LogMAR converted from BCVA in individual eyes of sarcoidosis patients before surgery and at 12 months after surgery. B, C, and D: The mean LogMAR before surgery and at 1 week, 1, 3, 6, and 12 months after surgery in all eyes (B), eyes with MIVS only (C), and eyes with MIVS and phacoemulsification (D). ANOVA = analysis of variance, LogMAR = log of the minimum angle of resolution, MIVS = microincision vitrectomy surgery.
© Copyright Policy - open-access
Related In: Results  -  Collection

License
Show All Figures
getmorefigures.php?uid=PMC4554185&req=5

Figure 1: Outcomes of visual acuity before and after MIVS. A: LogMAR converted from BCVA in individual eyes of sarcoidosis patients before surgery and at 12 months after surgery. B, C, and D: The mean LogMAR before surgery and at 1 week, 1, 3, 6, and 12 months after surgery in all eyes (B), eyes with MIVS only (C), and eyes with MIVS and phacoemulsification (D). ANOVA = analysis of variance, LogMAR = log of the minimum angle of resolution, MIVS = microincision vitrectomy surgery.
Mentions: The BCVA converted to LogMAR (log of the minimum angle of resolution) before surgery and after 1 week, 1, 3, 6, and 12 months is shown in Figure 1. Visual acuity was improved in 20 (83.3%) of 24 eyes after 12 months, 16 eyes (66.7%) showed improvement of more than 2 lines, whereas 4 eyes (16.7%) showed worsened or unchanged visual acuity (Figure 1A). The mean LogMAR in all eyes decreased from 1.14 ± 1.18 before surgery to 0.43 ± 0.55 at 1 week, 0.47 ± 0.74 at 1 month, 0.43 ± 0.73 at 3 months, 0.35 ± 0.67 at 6 months, and 0.36 ± 0.79 at 12 months after surgery, and significant improvements (P = .0028) were observed from 1 week (Figure 1B). When the cases were classified into MIVS only group and MIVS with phacoemulsification group, the mean LogMAR in MIVS only group was 1.26 ± 1.52 before surgery, and changed to 0.86 ± 0.92 at 1 week, 1.07 ± 1.35 after 1 month, 1.24 ± 1.51 at 3 months, 1.02 ± 1.72 at 6 months, and 1.03 ± 1.40 at 12 months (Table 2). There were no significant differences (P = .47) (Figure 1C). In MIVS with phacoemulsification group, the mean LogMAR was 1.05 ± 1.12 before surgery, changed to 0.34 ± 0.51 at 1 week, 0.26 ± 0.35 at 1 month, 0.23 ± 0.36 at 3 months, 0.21 ± 0.35 at 6 months, and 0.23 ± 0.41 at 12 months, and significantly decreased (P = .0027) after 1 week (Figure 1D).

Bottom Line: The mean LogMAR was significantly improved from 1.14 ± 1.18 to 0.36 ± 0.79 in all eyes and 0.83 ± 0.86 to 0.23 ± 0.41 in eyes with MIVS and phacoemulsification, although no improvement was observed in eyes with MIVS only.Significant decrease of the mean anterior inflammation score was observed after 1 month in eyes with MIVS only and after 12 months in eyes with MIVS and phacoemulsification, and the mean posterior inflammation scores decreased after 1 week in all eyes.There was no case in which ocular inflammation was exacerbated by surgical stress.

View Article: PubMed Central - PubMed

Affiliation: From the Department of Ophthalmology, National Defense Medical College.

ABSTRACT
We evaluate the outcomes of microincision vitrectomy surgery (MIVS) using wide-viewing system for complications with ocular sarcoidosis resistance to medical treatment.Consecutive clinical records of 24 eyes (19 patients) with complications of ocular sarcoidosis underwent MIVS between April 2010 and December 2013 were retrospectively reviewed. MIVS and phacoemulsification were performed in 18 eyes and MIVS only in 6 eyes. Best-corrected visual acuity (BCVA), inflammation scores in the anterior segment and in the posterior segment, and central retinal thickness (CRT) of eyes with cystoid macular edema (CME) before surgery and after 1 week, 1, 3, 6, and 12 months were evaluated.LogMAR (log of the minimum angle of resolution) converted from BCVA was improved in 83.3% after 12 months and 66.7% showed improvement of more than 2 lines. The mean LogMAR was significantly improved from 1.14 ± 1.18 to 0.36 ± 0.79 in all eyes and 0.83 ± 0.86 to 0.23 ± 0.41 in eyes with MIVS and phacoemulsification, although no improvement was observed in eyes with MIVS only. Significant decrease of the mean anterior inflammation score was observed after 1 month in eyes with MIVS only and after 12 months in eyes with MIVS and phacoemulsification, and the mean posterior inflammation scores decreased after 1 week in all eyes. In eyes with preoperative CME, mean CRT was significantly decreased from 1 week after surgery. There was no case in which ocular inflammation was exacerbated by surgical stress. Improvement of visual acuity and resolution of ocular inflammation could be achieved by MIVS using wide-viewing system for complications of ocular sarcoidosis.

Show MeSH
Related in: MedlinePlus