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Genital donovanosis with malignant transformation: An interesting case report.

Sri KN, Chowdary AS, Reddy BS - Indian J Sex Transm Dis (2014 Jul-Dec)

Bottom Line: It became uncommon due to indiscriminate use of broad spectrum antibiotics.In recent years, much interest is being focused on this condition because genital ulcers facilitate HIV infection.We report an interesting episode of genital donovanosis complicated with squamous cell carcinoma in a middle aged female for its rarity and clinical interest.

View Article: PubMed Central - PubMed

Affiliation: Department of Dermatology, Mamata Medical College and Hospital, Khammam, Telangana, India.

ABSTRACT
Donovanosis is a chronic indolent sexually transmitted granulomatous ulceration of genito-inguinal region, caused by Calymmatobacterium granulomatis. It became uncommon due to indiscriminate use of broad spectrum antibiotics. In recent years, much interest is being focused on this condition because genital ulcers facilitate HIV infection. We report an interesting episode of genital donovanosis complicated with squamous cell carcinoma in a middle aged female for its rarity and clinical interest.

No MeSH data available.


Related in: MedlinePlus

Tissue smear showing Donovan bodies
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Figure 2: Tissue smear showing Donovan bodies

Mentions: Tissue smear from the edge of the ulcer showed pink ovoid bodies containing dark blue nuclei with bipolar condensation lying within and also outside of large monocytes [Figure 2]. A clinical diagnosis of donovanosis was made based on the smear report. Serology for HIV, hepatitis and Venereal Disease Research Laboratory were nonreactive.


Genital donovanosis with malignant transformation: An interesting case report.

Sri KN, Chowdary AS, Reddy BS - Indian J Sex Transm Dis (2014 Jul-Dec)

Tissue smear showing Donovan bodies
© Copyright Policy - open-access
Related In: Results  -  Collection

License
Show All Figures
getmorefigures.php?uid=PMC4553842&req=5

Figure 2: Tissue smear showing Donovan bodies
Mentions: Tissue smear from the edge of the ulcer showed pink ovoid bodies containing dark blue nuclei with bipolar condensation lying within and also outside of large monocytes [Figure 2]. A clinical diagnosis of donovanosis was made based on the smear report. Serology for HIV, hepatitis and Venereal Disease Research Laboratory were nonreactive.

Bottom Line: It became uncommon due to indiscriminate use of broad spectrum antibiotics.In recent years, much interest is being focused on this condition because genital ulcers facilitate HIV infection.We report an interesting episode of genital donovanosis complicated with squamous cell carcinoma in a middle aged female for its rarity and clinical interest.

View Article: PubMed Central - PubMed

Affiliation: Department of Dermatology, Mamata Medical College and Hospital, Khammam, Telangana, India.

ABSTRACT
Donovanosis is a chronic indolent sexually transmitted granulomatous ulceration of genito-inguinal region, caused by Calymmatobacterium granulomatis. It became uncommon due to indiscriminate use of broad spectrum antibiotics. In recent years, much interest is being focused on this condition because genital ulcers facilitate HIV infection. We report an interesting episode of genital donovanosis complicated with squamous cell carcinoma in a middle aged female for its rarity and clinical interest.

No MeSH data available.


Related in: MedlinePlus