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Co-infection of human immunodeficiency virus and sexually transmitted infections in circumcised and uncircumcised cases in India.

Nayyar C, Chander R, Gupta P, Sherwal BL - Indian J Sex Transm Dis (2014 Jul-Dec)

Bottom Line: Male circumcision is being considered as strategy to reduce the burden of HIV/AIDS.The coinfection of HIV and STIs in circumcised and uncircumcised cases was found out.The coinfection rate in uncircumcised cases was found to be higher (29.2% in males and 39.2% in females) as compared to the circumcised cases (14.2% in males and 13.6% in females).

View Article: PubMed Central - PubMed

Affiliation: Department of Microbiology, Lady Hardinge Medical College, New Delhi, India.

ABSTRACT

Background: Acquired Immunodeficiency Syndrome (AIDS), is now one of the greatest challenges facing the world. Sexual transmission is the primary route of human immunodeficiency virus infection worldwide. Male circumcision is being considered as strategy to reduce the burden of HIV/AIDS.

Material and methods: The present study was conducted on 200 HIV positive clients. They were screened for bacterial causes of STIs (Chlamydia trachomatis, Neisseria gonorrhoeae, Treponema pallidum and Gardnerella vaginalis).

Results: There were 138 males and 62 females. The males were examined and the circumcision status was observed. In the females, circumcision status of their male partners was observed. The coinfection of HIV and STIs in circumcised and uncircumcised cases was found out. Diagnosis was made using standard tests. A total of 23% cases were diagnosed to have HIV -STI coinfection. Most common diagnosed diseases were Chlamydia (10%), Gonorrhoea (9%), Bacterial Vaginosis (4.8%) and Syphilis (2.5%). The coinfection rate in uncircumcised cases was found to be higher (29.2% in males and 39.2% in females) as compared to the circumcised cases (14.2% in males and 13.6% in females).

Conclusion: The present study suggests that circumcision is a protective factor for acquisition of STIs in HIV positive clients but other factors like sexual behaviours, use of barrier contraceptives, drug abuse etc also play a role.

No MeSH data available.


Related in: MedlinePlus

Co-infection of human immunodeficiency virus and sexually transmitted infections in circumcised and uncircumcised cases
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Figure 2: Co-infection of human immunodeficiency virus and sexually transmitted infections in circumcised and uncircumcised cases

Mentions: Co-infection of Chlamydia was found in 5.3% of circumcised males against 10.9% in uncircumcised males. In females, Chlamydia disease was present in 9% of females with circumcised male partners and 21.4% in those with uncircumcised male partners. Gonorrhea was diagnosed in 7.1% of circumcised males when compared to 14.6% in uncircumcised males, 0% in females with circumcised male partners and 7.1% in females with uncircumcised male partners. Syphilis was diagnosed in 1.7% circumcised males and 3.6% in uncircumcised males. None of females with circumcised male partners had syphilis, whereas 3.5% with uncircumcised male partner had syphilis. Among females with circumcised male partners 4.5% had bacterial vaginosis as compared to 7.1% in females with uncircumcised male partners [Table 1 and Figure 2].


Co-infection of human immunodeficiency virus and sexually transmitted infections in circumcised and uncircumcised cases in India.

Nayyar C, Chander R, Gupta P, Sherwal BL - Indian J Sex Transm Dis (2014 Jul-Dec)

Co-infection of human immunodeficiency virus and sexually transmitted infections in circumcised and uncircumcised cases
© Copyright Policy - open-access
Related In: Results  -  Collection

License
Show All Figures
getmorefigures.php?uid=PMC4553838&req=5

Figure 2: Co-infection of human immunodeficiency virus and sexually transmitted infections in circumcised and uncircumcised cases
Mentions: Co-infection of Chlamydia was found in 5.3% of circumcised males against 10.9% in uncircumcised males. In females, Chlamydia disease was present in 9% of females with circumcised male partners and 21.4% in those with uncircumcised male partners. Gonorrhea was diagnosed in 7.1% of circumcised males when compared to 14.6% in uncircumcised males, 0% in females with circumcised male partners and 7.1% in females with uncircumcised male partners. Syphilis was diagnosed in 1.7% circumcised males and 3.6% in uncircumcised males. None of females with circumcised male partners had syphilis, whereas 3.5% with uncircumcised male partner had syphilis. Among females with circumcised male partners 4.5% had bacterial vaginosis as compared to 7.1% in females with uncircumcised male partners [Table 1 and Figure 2].

Bottom Line: Male circumcision is being considered as strategy to reduce the burden of HIV/AIDS.The coinfection of HIV and STIs in circumcised and uncircumcised cases was found out.The coinfection rate in uncircumcised cases was found to be higher (29.2% in males and 39.2% in females) as compared to the circumcised cases (14.2% in males and 13.6% in females).

View Article: PubMed Central - PubMed

Affiliation: Department of Microbiology, Lady Hardinge Medical College, New Delhi, India.

ABSTRACT

Background: Acquired Immunodeficiency Syndrome (AIDS), is now one of the greatest challenges facing the world. Sexual transmission is the primary route of human immunodeficiency virus infection worldwide. Male circumcision is being considered as strategy to reduce the burden of HIV/AIDS.

Material and methods: The present study was conducted on 200 HIV positive clients. They were screened for bacterial causes of STIs (Chlamydia trachomatis, Neisseria gonorrhoeae, Treponema pallidum and Gardnerella vaginalis).

Results: There were 138 males and 62 females. The males were examined and the circumcision status was observed. In the females, circumcision status of their male partners was observed. The coinfection of HIV and STIs in circumcised and uncircumcised cases was found out. Diagnosis was made using standard tests. A total of 23% cases were diagnosed to have HIV -STI coinfection. Most common diagnosed diseases were Chlamydia (10%), Gonorrhoea (9%), Bacterial Vaginosis (4.8%) and Syphilis (2.5%). The coinfection rate in uncircumcised cases was found to be higher (29.2% in males and 39.2% in females) as compared to the circumcised cases (14.2% in males and 13.6% in females).

Conclusion: The present study suggests that circumcision is a protective factor for acquisition of STIs in HIV positive clients but other factors like sexual behaviours, use of barrier contraceptives, drug abuse etc also play a role.

No MeSH data available.


Related in: MedlinePlus