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Treatment of Verruca Vulgaris in Both External Auditory Canals Using Bleomycin Injections.

Lee JH, Burm JS, Yang WY, Kang SY, Byun SW - Clin Exp Otorhinolaryngol (2015)

Bottom Line: However, we performed intralesional bleomycin injections for treatment.Twice intralesional bleomycin injections at one-month intervals had excellent results without recurrence, ulceration or scar formation.This result indicates that bleomycin injections may prove to be an effective first-line treatment of verruca in the EAC.

View Article: PubMed Central - PubMed

Affiliation: Department of Plastic and Reconstructive Surgery, Kyung Hee University School of Medicine, Seoul, Korea.

ABSTRACT
Verruca vulgaris is caused by human papillomavirus (HPV) infections. Verruca in the external auditory canal (EAC) has rarely been reported. A previous case report introduced surgical excision as a treatment for verruca in the EAC. We present a case of verruca vulgaris in both EACs that was successfully treated with an intralesional bleomycin injection. A 32-year-old male patient presented with ear fullness and palpable lumps in both EACs. Both of his canals were filled with multiple pinkish, papillomatous masses. Verruca vulgaris was confirmed by skin biopsy. An otolaryngologist referred this patient and recommended surgical excision. However, we performed intralesional bleomycin injections for treatment. Twice intralesional bleomycin injections at one-month intervals had excellent results without recurrence, ulceration or scar formation. This result indicates that bleomycin injections may prove to be an effective first-line treatment of verruca in the EAC.

No MeSH data available.


Related in: MedlinePlus

Histopathological section of verruca in the external auditory canals. It indicates verruca vulgaris with a central fibrovascular core covered by keratinizing squamous epithelium (H&E, ×12.5).
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Figure 2: Histopathological section of verruca in the external auditory canals. It indicates verruca vulgaris with a central fibrovascular core covered by keratinizing squamous epithelium (H&E, ×12.5).

Mentions: A 32-year-old male patient presented with ear fullness and palpable lumps in both EACs. The lumps were identified 18 months prior to the examination and the patient indicated that the lumps appeared to be getting larger. The patient had not undergone any specific treatment. Otoscopic examination revealed multiple pinkish, papillomatous masses that filled both of his EACs (Fig. 1A, B). The tympanic membrane and the surrounding tissue were intact. Verruca was confirmed by punch biopsy (Fig. 2). An otolaryngologist referred this patient and recommended surgical excision and skin grafting. However, we performed intralesional bleomycin injection, which is a simple and effective method for treatment of verruca vulgaris on the hands, feet or face.


Treatment of Verruca Vulgaris in Both External Auditory Canals Using Bleomycin Injections.

Lee JH, Burm JS, Yang WY, Kang SY, Byun SW - Clin Exp Otorhinolaryngol (2015)

Histopathological section of verruca in the external auditory canals. It indicates verruca vulgaris with a central fibrovascular core covered by keratinizing squamous epithelium (H&E, ×12.5).
© Copyright Policy - open-access
Related In: Results  -  Collection

License
Show All Figures
getmorefigures.php?uid=PMC4553363&req=5

Figure 2: Histopathological section of verruca in the external auditory canals. It indicates verruca vulgaris with a central fibrovascular core covered by keratinizing squamous epithelium (H&E, ×12.5).
Mentions: A 32-year-old male patient presented with ear fullness and palpable lumps in both EACs. The lumps were identified 18 months prior to the examination and the patient indicated that the lumps appeared to be getting larger. The patient had not undergone any specific treatment. Otoscopic examination revealed multiple pinkish, papillomatous masses that filled both of his EACs (Fig. 1A, B). The tympanic membrane and the surrounding tissue were intact. Verruca was confirmed by punch biopsy (Fig. 2). An otolaryngologist referred this patient and recommended surgical excision and skin grafting. However, we performed intralesional bleomycin injection, which is a simple and effective method for treatment of verruca vulgaris on the hands, feet or face.

Bottom Line: However, we performed intralesional bleomycin injections for treatment.Twice intralesional bleomycin injections at one-month intervals had excellent results without recurrence, ulceration or scar formation.This result indicates that bleomycin injections may prove to be an effective first-line treatment of verruca in the EAC.

View Article: PubMed Central - PubMed

Affiliation: Department of Plastic and Reconstructive Surgery, Kyung Hee University School of Medicine, Seoul, Korea.

ABSTRACT
Verruca vulgaris is caused by human papillomavirus (HPV) infections. Verruca in the external auditory canal (EAC) has rarely been reported. A previous case report introduced surgical excision as a treatment for verruca in the EAC. We present a case of verruca vulgaris in both EACs that was successfully treated with an intralesional bleomycin injection. A 32-year-old male patient presented with ear fullness and palpable lumps in both EACs. Both of his canals were filled with multiple pinkish, papillomatous masses. Verruca vulgaris was confirmed by skin biopsy. An otolaryngologist referred this patient and recommended surgical excision. However, we performed intralesional bleomycin injections for treatment. Twice intralesional bleomycin injections at one-month intervals had excellent results without recurrence, ulceration or scar formation. This result indicates that bleomycin injections may prove to be an effective first-line treatment of verruca in the EAC.

No MeSH data available.


Related in: MedlinePlus