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Evaluation of Hearing and Outer Hair Cell Function of Cochlea in Patients With Psoriatic Arthritis.

Akdag M, Uçmak D, Özkurt FE, Bozkurt M, Akkurt ZM, Topçu İ - Clin Exp Otorhinolaryngol (2015)

Bottom Line: This difference was evident, especially at high frequencies.There was no statistically significant difference between the ages and genders of the patient and control groups (P>0.05).Both audiological and otoacoustic emissions were not significantly different between right and left ear (P>0.05).

View Article: PubMed Central - PubMed

Affiliation: Department of Otorhinolaryngology-Head and Neck Surgery, Dicle University Faculty of Medicine, Diyarbakir, Turkey.

ABSTRACT

Objectives: The aim of this study was to investigate hearing and outer cells function in patients with psoriatic arthritis. Our investigation was a prospective case control study.

Methods: A total of 31 psoriatic arthritis patients (62 ears) and 31 healthy control subjects (62 ears) were enrolled in the study. We investigated hearing changes of patients and controls via pure tone audiometry, speech discrimination scores, tympanometry, acoustic reflex, and transient product otoacoustic emission.

Results: The mean age of psoriatic arthritis patients was 36.1±8.5 years (range, 14 to 62 years). The average age of the control group was 37.9±8.1 years (range, 16 to 62 years). There were statistically significant differences between pure tone audiometry in all frequencies and right and left emission at the 4.0 and 1.0 in psoriatic arthritis patients versus controls (P<0.05). This difference was evident, especially at high frequencies. There was no statistically significant difference between the ages and genders of the patient and control groups (P>0.05). Both audiological and otoacoustic emissions were not significantly different between right and left ear (P>0.05).

Conclusion: Based on the audiological and otoacoustic findings; it is likely that the cochlear outer hair cells become subtly damaged in psoriatic arthritis patients, consequently leading to changes in hearing thresholds. These data suggest that it is important to screen psoriatic arthritis patients for hearing changes with otoacoustic emissions and audiologic tests regularly.

No MeSH data available.


Related in: MedlinePlus

Left otoacoustic emission graphic of frequency and sound noise ratio changes of patient and control groups. Frequency of left otoacoustic emission: 1.0 Hz, P=0.005; 1.4 Hz, P=0.213; 2.0 Hz, P=0.357; 2.8 Hz, P=0.212; 4.0 Hz, P=0.076. Mann-Whitney U-test.
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Figure 4: Left otoacoustic emission graphic of frequency and sound noise ratio changes of patient and control groups. Frequency of left otoacoustic emission: 1.0 Hz, P=0.005; 1.4 Hz, P=0.213; 2.0 Hz, P=0.357; 2.8 Hz, P=0.212; 4.0 Hz, P=0.076. Mann-Whitney U-test.

Mentions: Differences in TEOAE were statistically significant at certain frequencies (right 4.0 and left emission at the 1.0) when contrasting the control and PsA groups (P<0.05). SNR values with frequency of TEOAE findings for all study subjects are summarized in Figs. 3, 4. There wasn't a significant association between the length of time having PsA and the severity of hearing loss (P>0.05). No correlation was identified between the PASI measurement of PsA severity and hearing loss (P>0.05) except at right ear audio at the 2,000 Hz. Also both audiological and OAEs were not significant difference between right and left ear (P>0.05).


Evaluation of Hearing and Outer Hair Cell Function of Cochlea in Patients With Psoriatic Arthritis.

Akdag M, Uçmak D, Özkurt FE, Bozkurt M, Akkurt ZM, Topçu İ - Clin Exp Otorhinolaryngol (2015)

Left otoacoustic emission graphic of frequency and sound noise ratio changes of patient and control groups. Frequency of left otoacoustic emission: 1.0 Hz, P=0.005; 1.4 Hz, P=0.213; 2.0 Hz, P=0.357; 2.8 Hz, P=0.212; 4.0 Hz, P=0.076. Mann-Whitney U-test.
© Copyright Policy - open-access
Related In: Results  -  Collection

License
Show All Figures
getmorefigures.php?uid=PMC4553344&req=5

Figure 4: Left otoacoustic emission graphic of frequency and sound noise ratio changes of patient and control groups. Frequency of left otoacoustic emission: 1.0 Hz, P=0.005; 1.4 Hz, P=0.213; 2.0 Hz, P=0.357; 2.8 Hz, P=0.212; 4.0 Hz, P=0.076. Mann-Whitney U-test.
Mentions: Differences in TEOAE were statistically significant at certain frequencies (right 4.0 and left emission at the 1.0) when contrasting the control and PsA groups (P<0.05). SNR values with frequency of TEOAE findings for all study subjects are summarized in Figs. 3, 4. There wasn't a significant association between the length of time having PsA and the severity of hearing loss (P>0.05). No correlation was identified between the PASI measurement of PsA severity and hearing loss (P>0.05) except at right ear audio at the 2,000 Hz. Also both audiological and OAEs were not significant difference between right and left ear (P>0.05).

Bottom Line: This difference was evident, especially at high frequencies.There was no statistically significant difference between the ages and genders of the patient and control groups (P>0.05).Both audiological and otoacoustic emissions were not significantly different between right and left ear (P>0.05).

View Article: PubMed Central - PubMed

Affiliation: Department of Otorhinolaryngology-Head and Neck Surgery, Dicle University Faculty of Medicine, Diyarbakir, Turkey.

ABSTRACT

Objectives: The aim of this study was to investigate hearing and outer cells function in patients with psoriatic arthritis. Our investigation was a prospective case control study.

Methods: A total of 31 psoriatic arthritis patients (62 ears) and 31 healthy control subjects (62 ears) were enrolled in the study. We investigated hearing changes of patients and controls via pure tone audiometry, speech discrimination scores, tympanometry, acoustic reflex, and transient product otoacoustic emission.

Results: The mean age of psoriatic arthritis patients was 36.1±8.5 years (range, 14 to 62 years). The average age of the control group was 37.9±8.1 years (range, 16 to 62 years). There were statistically significant differences between pure tone audiometry in all frequencies and right and left emission at the 4.0 and 1.0 in psoriatic arthritis patients versus controls (P<0.05). This difference was evident, especially at high frequencies. There was no statistically significant difference between the ages and genders of the patient and control groups (P>0.05). Both audiological and otoacoustic emissions were not significantly different between right and left ear (P>0.05).

Conclusion: Based on the audiological and otoacoustic findings; it is likely that the cochlear outer hair cells become subtly damaged in psoriatic arthritis patients, consequently leading to changes in hearing thresholds. These data suggest that it is important to screen psoriatic arthritis patients for hearing changes with otoacoustic emissions and audiologic tests regularly.

No MeSH data available.


Related in: MedlinePlus