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Evaluation of Hearing and Outer Hair Cell Function of Cochlea in Patients With Psoriatic Arthritis.

Akdag M, Uçmak D, Özkurt FE, Bozkurt M, Akkurt ZM, Topçu İ - Clin Exp Otorhinolaryngol (2015)

Bottom Line: This difference was evident, especially at high frequencies.There was no statistically significant difference between the ages and genders of the patient and control groups (P>0.05).Both audiological and otoacoustic emissions were not significantly different between right and left ear (P>0.05).

View Article: PubMed Central - PubMed

Affiliation: Department of Otorhinolaryngology-Head and Neck Surgery, Dicle University Faculty of Medicine, Diyarbakir, Turkey.

ABSTRACT

Objectives: The aim of this study was to investigate hearing and outer cells function in patients with psoriatic arthritis. Our investigation was a prospective case control study.

Methods: A total of 31 psoriatic arthritis patients (62 ears) and 31 healthy control subjects (62 ears) were enrolled in the study. We investigated hearing changes of patients and controls via pure tone audiometry, speech discrimination scores, tympanometry, acoustic reflex, and transient product otoacoustic emission.

Results: The mean age of psoriatic arthritis patients was 36.1±8.5 years (range, 14 to 62 years). The average age of the control group was 37.9±8.1 years (range, 16 to 62 years). There were statistically significant differences between pure tone audiometry in all frequencies and right and left emission at the 4.0 and 1.0 in psoriatic arthritis patients versus controls (P<0.05). This difference was evident, especially at high frequencies. There was no statistically significant difference between the ages and genders of the patient and control groups (P>0.05). Both audiological and otoacoustic emissions were not significantly different between right and left ear (P>0.05).

Conclusion: Based on the audiological and otoacoustic findings; it is likely that the cochlear outer hair cells become subtly damaged in psoriatic arthritis patients, consequently leading to changes in hearing thresholds. These data suggest that it is important to screen psoriatic arthritis patients for hearing changes with otoacoustic emissions and audiologic tests regularly.

No MeSH data available.


Related in: MedlinePlus

Left audiometric graphic of frequency and pure tone thresholds of patient and control groups. Frequency of left audiometry: 250 Hz, P=0.013; 500 Hz, P=0.023; 1,000 Hz, P=0.007; 2,000 Hz, P=0.002; 4,000 Hz, P=0.002; 6,000 Hz, P<0.001.
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Figure 2: Left audiometric graphic of frequency and pure tone thresholds of patient and control groups. Frequency of left audiometry: 250 Hz, P=0.013; 500 Hz, P=0.023; 1,000 Hz, P=0.007; 2,000 Hz, P=0.002; 4,000 Hz, P=0.002; 6,000 Hz, P<0.001.

Mentions: Normal peak compliance, gradient, peak pressure, ear canal volume, and acoustic reflexes were obtained with a 226-Hz probe. Discrepancies in SDSs were not observed between patient and control groups (P>0.05). The mean PTA for patients with PsA was 15.2±5.7 dB, and the mean PTA for the control group was 8.5±4.4 dB. Also the mean high frequency PTA as 26.7±6.8 for patients with PsA, and the mean PTA for the control group was 8.8±3 dB. The bone conduction threshold was taken into account for patients with PsA since an air-bone gap was not present. Comparing PTA between control and PsA subjects, statistically significant differences were observed over all frequencies (P<0.05). This difference was evident, especially at high frequencies for right and left ear (Figs. 1, 2). There was no statistically significant differences in SDS between PsA groups and control groups (P>0.05). In addition, age and PTA values were not correlated (P>0.05).


Evaluation of Hearing and Outer Hair Cell Function of Cochlea in Patients With Psoriatic Arthritis.

Akdag M, Uçmak D, Özkurt FE, Bozkurt M, Akkurt ZM, Topçu İ - Clin Exp Otorhinolaryngol (2015)

Left audiometric graphic of frequency and pure tone thresholds of patient and control groups. Frequency of left audiometry: 250 Hz, P=0.013; 500 Hz, P=0.023; 1,000 Hz, P=0.007; 2,000 Hz, P=0.002; 4,000 Hz, P=0.002; 6,000 Hz, P<0.001.
© Copyright Policy - open-access
Related In: Results  -  Collection

License
Show All Figures
getmorefigures.php?uid=PMC4553344&req=5

Figure 2: Left audiometric graphic of frequency and pure tone thresholds of patient and control groups. Frequency of left audiometry: 250 Hz, P=0.013; 500 Hz, P=0.023; 1,000 Hz, P=0.007; 2,000 Hz, P=0.002; 4,000 Hz, P=0.002; 6,000 Hz, P<0.001.
Mentions: Normal peak compliance, gradient, peak pressure, ear canal volume, and acoustic reflexes were obtained with a 226-Hz probe. Discrepancies in SDSs were not observed between patient and control groups (P>0.05). The mean PTA for patients with PsA was 15.2±5.7 dB, and the mean PTA for the control group was 8.5±4.4 dB. Also the mean high frequency PTA as 26.7±6.8 for patients with PsA, and the mean PTA for the control group was 8.8±3 dB. The bone conduction threshold was taken into account for patients with PsA since an air-bone gap was not present. Comparing PTA between control and PsA subjects, statistically significant differences were observed over all frequencies (P<0.05). This difference was evident, especially at high frequencies for right and left ear (Figs. 1, 2). There was no statistically significant differences in SDS between PsA groups and control groups (P>0.05). In addition, age and PTA values were not correlated (P>0.05).

Bottom Line: This difference was evident, especially at high frequencies.There was no statistically significant difference between the ages and genders of the patient and control groups (P>0.05).Both audiological and otoacoustic emissions were not significantly different between right and left ear (P>0.05).

View Article: PubMed Central - PubMed

Affiliation: Department of Otorhinolaryngology-Head and Neck Surgery, Dicle University Faculty of Medicine, Diyarbakir, Turkey.

ABSTRACT

Objectives: The aim of this study was to investigate hearing and outer cells function in patients with psoriatic arthritis. Our investigation was a prospective case control study.

Methods: A total of 31 psoriatic arthritis patients (62 ears) and 31 healthy control subjects (62 ears) were enrolled in the study. We investigated hearing changes of patients and controls via pure tone audiometry, speech discrimination scores, tympanometry, acoustic reflex, and transient product otoacoustic emission.

Results: The mean age of psoriatic arthritis patients was 36.1±8.5 years (range, 14 to 62 years). The average age of the control group was 37.9±8.1 years (range, 16 to 62 years). There were statistically significant differences between pure tone audiometry in all frequencies and right and left emission at the 4.0 and 1.0 in psoriatic arthritis patients versus controls (P<0.05). This difference was evident, especially at high frequencies. There was no statistically significant difference between the ages and genders of the patient and control groups (P>0.05). Both audiological and otoacoustic emissions were not significantly different between right and left ear (P>0.05).

Conclusion: Based on the audiological and otoacoustic findings; it is likely that the cochlear outer hair cells become subtly damaged in psoriatic arthritis patients, consequently leading to changes in hearing thresholds. These data suggest that it is important to screen psoriatic arthritis patients for hearing changes with otoacoustic emissions and audiologic tests regularly.

No MeSH data available.


Related in: MedlinePlus