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Utilization of Hyaluronate and Incidence of Septic Knee Arthritis in Adults: Results from the Korean National Claim Registry.

Lee YK, Kim KC, Ha YC, Koo KH - Clin Orthop Surg (2015)

Bottom Line: All new admissions to the clinics or hospitals for septic knees were recorded in the HIRA database which was established by the Korean government and covers the Korean population using the International Classification of Diseases-10 revision code.In 2012, the incidence of septic knees was 2.7 per 100,000 persons in men and 4.2 per 100,000 persons in women, respectively.The age-adjusted incidence of septic knees increased by 6.7% per year (95% confidence interval, 3.3 to 10.1), and the annual number of prescriptions of hyaluronate increased about 1.5-fold during the study period.

View Article: PubMed Central - PubMed

Affiliation: Department of Orthopedic Surgery, Seoul National University Bundang Hospital, Seongnam, Korea.

ABSTRACT

Background: Septic arthritis of the knee has been reported recently in adult patients who were administered hyaluronate. We evaluated the incidence of septic knees and the utilization of hyaluronate in the Korean adult population using nationwide data from the Health Insurance Review and Assessment Service (HIRA).

Methods: All new admissions to the clinics or hospitals for septic knees were recorded in the HIRA database which was established by the Korean government and covers the Korean population using the International Classification of Diseases-10 revision code. We evaluated the incidence of septic arthritis of the knees in the population above 50 years of age. Hyaluronate prescription data was also collected from the HIRA database.

Results: In 2012, the incidence of septic knees was 2.7 per 100,000 persons in men and 4.2 per 100,000 persons in women, respectively. The age-adjusted incidence of septic knees increased by 6.7% per year (95% confidence interval, 3.3 to 10.1), and the annual number of prescriptions of hyaluronate increased about 1.5-fold during the study period.

Conclusions: Cautious aseptic technique is required when hyaluronate is administered in adult patients with osteoarthritis of the knee due to the concerns of the risk of septic arthritis.

No MeSH data available.


Related in: MedlinePlus

The number of septic knees (A) and the age-adjusted incidence of septic knees (B) in the population above 50 years of age from 2008 to 2012.
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Figure 1: The number of septic knees (A) and the age-adjusted incidence of septic knees (B) in the population above 50 years of age from 2008 to 2012.

Mentions: In 2012, among the population aged 50 years or older, the crude overall incidences of septic knees were 2.7 per 100,000 persons in men and 4.2 per 100,000 persons in women, respectively (Table 1). The absolute number of septic knees increased during the study period (Fig. 1). The age-adjusted incidence of septic knee increased by 6.7% per year (95% CI, 3.3 to 10.1) (Table 2 and Fig. 1). In addition, over the 5-year study period, the annual number of prescriptions of hyaluronate increased about 1.5-fold (Fig. 2).


Utilization of Hyaluronate and Incidence of Septic Knee Arthritis in Adults: Results from the Korean National Claim Registry.

Lee YK, Kim KC, Ha YC, Koo KH - Clin Orthop Surg (2015)

The number of septic knees (A) and the age-adjusted incidence of septic knees (B) in the population above 50 years of age from 2008 to 2012.
© Copyright Policy - open-access
Related In: Results  -  Collection

License
Show All Figures
getmorefigures.php?uid=PMC4553279&req=5

Figure 1: The number of septic knees (A) and the age-adjusted incidence of septic knees (B) in the population above 50 years of age from 2008 to 2012.
Mentions: In 2012, among the population aged 50 years or older, the crude overall incidences of septic knees were 2.7 per 100,000 persons in men and 4.2 per 100,000 persons in women, respectively (Table 1). The absolute number of septic knees increased during the study period (Fig. 1). The age-adjusted incidence of septic knee increased by 6.7% per year (95% CI, 3.3 to 10.1) (Table 2 and Fig. 1). In addition, over the 5-year study period, the annual number of prescriptions of hyaluronate increased about 1.5-fold (Fig. 2).

Bottom Line: All new admissions to the clinics or hospitals for septic knees were recorded in the HIRA database which was established by the Korean government and covers the Korean population using the International Classification of Diseases-10 revision code.In 2012, the incidence of septic knees was 2.7 per 100,000 persons in men and 4.2 per 100,000 persons in women, respectively.The age-adjusted incidence of septic knees increased by 6.7% per year (95% confidence interval, 3.3 to 10.1), and the annual number of prescriptions of hyaluronate increased about 1.5-fold during the study period.

View Article: PubMed Central - PubMed

Affiliation: Department of Orthopedic Surgery, Seoul National University Bundang Hospital, Seongnam, Korea.

ABSTRACT

Background: Septic arthritis of the knee has been reported recently in adult patients who were administered hyaluronate. We evaluated the incidence of septic knees and the utilization of hyaluronate in the Korean adult population using nationwide data from the Health Insurance Review and Assessment Service (HIRA).

Methods: All new admissions to the clinics or hospitals for septic knees were recorded in the HIRA database which was established by the Korean government and covers the Korean population using the International Classification of Diseases-10 revision code. We evaluated the incidence of septic arthritis of the knees in the population above 50 years of age. Hyaluronate prescription data was also collected from the HIRA database.

Results: In 2012, the incidence of septic knees was 2.7 per 100,000 persons in men and 4.2 per 100,000 persons in women, respectively. The age-adjusted incidence of septic knees increased by 6.7% per year (95% confidence interval, 3.3 to 10.1), and the annual number of prescriptions of hyaluronate increased about 1.5-fold during the study period.

Conclusions: Cautious aseptic technique is required when hyaluronate is administered in adult patients with osteoarthritis of the knee due to the concerns of the risk of septic arthritis.

No MeSH data available.


Related in: MedlinePlus